Protein Alignment spn-E and F52B5.3

DIOPT Version :9

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_492260.1
• Gene: F52B5.3 / 172615
• WormBaseID: WBGene00009922
• Length: 1425
• Species: Caenorhabditis elegans
• Alignment Length: 1112
• Identity: 277/1112 - (24%)
• Similarity: 423/1112 - (38%)
• Gaps: 376/1112 - (33%)

  Fly    10 DFSKELKRVA----------------AAPQGYISSDPRL----------MATKFKSSEVPNRELI 48
            |..||.:|||                ..|.|   .|.|.          |.||....| |:|.:|
 Worm    36 DTRKEYRRVANEIIRSFLKSGQKNTTLEPMG---RDQRKVMHEVALLNEMTTKSHGRE-PDRYMI 96

  Fly    49 GTDYVSKIVAKEKCLLNGTLLNEQPQGKRIRTLDDLD--------TDDEGEE--TEIRRDDEYYK 103
                :||.|.:   |...||:..:|.......|..|.        |.:|.:|  ||.:....:..
 Worm    97 ----LSKRVNR---LSKSTLVATEPITPSFECLQKLSKFVEKHPITREEMDEFLTETQTKQMHTT 154

  Fly   104 KFRFN--------------LNRDKNLSIYAKR--EEILAAINAHPVVIIKGETGCGKTTQVPQYI 152
            |...:              |.:.:| |:.|.:  :::|.:|::..||||.|.|||||||||||:|
 Worm   155 KGHISDRMVIPPKSKCSKELQKVRN-SLPASKYCDQVLKSISSCNVVIISGGTGCGKTTQVPQFI 218

  Fly   153 LDEAYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTG 217
            ||||:::.|:..::|||||||||||||.||.:||.........:||.|....| :||.|.|||||
 Worm   219 LDEAHENNKHVRVMVTQPRRIAAISIAERVARERGEPIGRTVGYQVRLDSRRS-DDTVLTYCTTG 282

  Fly   218 VLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDA--KELS 280
            |||..|.::...:..||||:||:|||:.|.|:|||.:|..|.... .:|:|||||||:.  :..|
 Worm   283 VLLRMLTSDPVASGITHIVMDEIHEREINTDYLLIALRECLKMRP-DLKVILMSATIEGNMQLFS 346

  Fly   281 DYFTTTNSIPPVITTNHRRKHSIEKFYRDQLGSII--------------------WNEE------ 319
            :||  .|....||.. ..|...::.||.||:.::.                    |.:|
 Worm   347 NYF--ENHSMDVIRI-ESRAFDVKVFYLDQILAMTGYQPPESKAFFSTAEYEEEDWKDEIEAVER 408

  Fly   320 ---DVGHQQVPE----------------------------------------INKHGYRAAVKII 341
               |...|:..:                                        |::...|..:.||
 Worm   409 EEKDKAKQRAADSSLSTLSKPVTKMAANTKRNSPIEEREWTSGPCSTPDGDIIDERAMRQYMNII 473

  Fly   342 --------------------VIIDNM--------------------------------------- 347
                                |.|:::
 Worm   474 GNPDIRPVITVEFRPTTPNSVFINDVKYTTNPNQSAQALLQQKRERCLMPRGPLTFTCENPASTT 538

  Fly   348 -----------------------------------------ERKAAIQSRQSY------------ 359
                                                     |.|.|:..|..|
 Worm   539 KSPPSPTPTLGISSGLAKFTPFGGFGEKQRISTLLEKKFKEELKTALPDRTVYYHPQMNDVVDKT 603

  Fly   360 ----------------------------DEALRY-------GAVLIFLPGIYEIDTMAENLTCML 389
                                        |:.::|       |.:|:||||..:|..|.:.:.|..
 Worm   604 DFSKLRFGEKYNLFYGSSSNNSVDYVLLDQVIQYLADSPVFGTILVFLPGYEDIQQMLKAIDCWK 668

  Fly   390 ENDPNIK-VSIVRCFSLMTPENQRDVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVK 453
            .:..|:| |.::...|.||..|..|:|...|...|||||.|||||:|||:.||.:|:|....|.|
 Worm   669 NSLKNMKNVIVLPLHSQMTSINHGDIFKSVPKDTRKIILATNIAEASITIEDVIFVVDTGKVKEK 733

  Fly   454 VTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNS 518
            ..|..:..|:|.:...:::|..||:||.||:.:|...|:..:..| ..|||..|.||.|..:.:.
 Worm   734 SFDHEAKLSTLTVKPIARSNADQRSGRAGRVANGYCIRLYTEQEY-NSMPETQIAEMKRAAIYDV 797

  Fly   519 VLKAKVLNMGSP-----VEILALALSPPNLSDIHNTILLLKEVGALYLTVDGIYD---------- 568
            .|.||:.   :|     .|.|:||..||....|...|..|:::||.|..:. |||
 Worm   798 TLHAKLF---APKTLKISEFLSLAPEPPEKESILQAITFLEQIGAFYTPIK-IYDNSGNEEGLKN 858

  Fly   569 ---------PLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLST--PGLFAHE 622
                     |.|.:||..|.:|:|||||.:.||:::.|.....|...:.:.|.|::  |.:.|..
 Worm   859 DEEAENSENPEDPELTDLGRLMARLPLDPQLSRMLLFGLALKCLTPIVNLVALLASREPYVLALS 923

  Fly   623 GGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIV-----ENGHDQESAIRWAKRFHVSLRS 682
            ..|.....   |.:..:....||       :|.|:.:.     :|...|.   ::.:...::..:
 Worm   924 EDRDLQSK---MKFEMAQQDLSD-------HLLYIRLCNEFCSKNNSQQN---QFCRDHFLNFST 975

  Fly   683 LKEI----HLLVQELRVRCTHLGLIPFPVNPNQ-----MMDDREKAI-----MLKVIIAGAFYPN 733
            ::.:    ..|::|| ||...:.     ::||:     :.|......     |::.:||...||.
 Worm   976 MRMVQGTRRQLLREL-VRAKLIN-----ISPNRDVLTVLTDHHFNQFSQCWPMIQAVIAAGCYPF 1034

  Fly   734 YFTRSKESCADTDRNIYQTISGHDPCRTVYFTNFKPAYM--GELYTRRIKELFQEVRIPPENMDV 796
            ....:.||      |:          :.|...|.|||::  ..:..::|.::.:..:.|.... |
 Worm  1035 IGVSASES------NL----------KKVQTFNDKPAFLHPSSMVKKQIVKMGKSEKSPRVEY-V 1082

  Fly   797 TFQEGSQ 803
            .|||..|
 Worm  1083 AFQEMCQ 1089

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	113..>697	CDD:224557	220/839 (26%)
		TUDOR	892..1016	CDD:395449
F52B5.3	NP_492260.1	R3H	21..100	CDD:214647	18/71 (25%)
		DEXDc	189..369	CDD:214692	88/184 (48%)
		DEXDc	198..338	CDD:238005	77/141 (55%)
		eIF3_subunit	393..>470	CDD:285763	6/76 (8%)
		Helicase_C	647..764	CDD:278689	46/116 (40%)
		HA2	869..948	CDD:214852	23/88 (26%)
		OB_NTP_bind	984..1116	CDD:285018	28/129 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820