Protein Alignment spn-E and dhx34

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: NP_001121459.1
• Gene: dhx34 / 100158553
• XenbaseID: XB-GENE-1009178
• Length: 1133
• Species: Xenopus tropicalis
• Alignment Length: 731
• Identity: 199/731 - (27%)
• Similarity: 329/731 - (45%)
• Gaps: 150/731 - (20%)

  Fly   114 NLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAISI 178
            :|.|:..:|:|::.::.|.||::.|:|||||:||||||:|     :..:.:|..|||||||.||:
 Frog   153 SLPIFQYKEKIISMVHKHQVVVVAGDTGCGKSTQVPQYLL-----AAGFGHIACTQPRRIACISL 212

  Fly   179 ANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHER 243
            |.||..|...|..:...:|:......| ..|::::.|.|:||..:..:.||..|..|::||||||
 Frog   213 AKRVGFESLNQYGSKVGYQIRFESSRS-PATKIVFITEGLLLRQIQRDSTLPQYQVIIVDEVHER 276

  Fly   244 DQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNSIPPVITTNHRRKHSIEKFYR 308
            ..:.||||.|:|:||.... .:|:|||||||:.|..|.||...    ||:.. ..|...|:..|:
 Frog   277 HLHSDFLLGVLRQLLILRP-DLKVILMSATINIKLFSGYFEQA----PVLQV-PGRLFPIQVIYQ 335

  Fly   309 DQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAIQSRQSYDEALRYGAVLIFLP 373
            .     |..||.|...:  :::...|...::            ||..:...||.   |.:||||.
 Frog   336 P-----IPQEETVSKSE--KLDPRPYLHVLQ------------AIDHKYPPDER---GDLLIFLS 378

  Fly   374 GIYEIDTMAENLTCMLENDPNIKVSIVRCFSLMTPENQRDVFNPPPPGFRKIILTTNIAESSITV 438
            |:.||.::.|.:.....:..  :..::...|.::..:|..||:..|.|.||.|::|||||:|:|:
 Frog   379 GVTEISSVQEAVQVYATHTQ--RWIVLPLHSTLSIADQDKVFDLAPVGVRKCIISTNIAETSVTI 441

  Fly   439 PDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHFYQREMP 503
            ..|.:|:|....|....|..:....|:..|.|:|:..||.||.||...|..||:..:..|....|
 Frog   442 DGVRFVLDSGKVKEMSFDPKAKMQRLQEFWISRASAEQRKGRAGRTGPGVCYRLYAESDYDAFSP 506

  Fly   504 EFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIHNTILLLKEVGALYLTVDGIYD 568
             :.:||:.|:.|.:.||:.|.:.:|:|...  ..:..|::|.|...|..|::.|||
 Frog   507 -YPVPEIQRVALDSLVLQMKSMELGNPRHF--PFIEQPSMSSIETAIFYLRDQGAL--------- 559

  Fly   569 PLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLS--TPGL----------FAH 621
            .::.:||..|.::::||:|....:::|||.:|:::|..:.||:.||  :|.|          .|.
 Frog   560 DINEELTPIGKLLAKLPVDVVIGKMLILGSLFSLVEPVLTIASALSVQSPILRNSTSNPEWGTAR 624

  Fly   622 EGGRSQLGDSFWMHYIFSDGSGSDLVAIW-----------------------RVY---------- 653
            :...|:.||.|.:..||::         |                       |:|
 Frog   625 KPLESEHGDPFTLLNIFNE---------WVQVKANQRSNSRKWCRRRGLEEQRLYEMANLRRQFK 680

  Fly   654 -------LTYLNIVENG--------HDQESAIRWAKRFH--VSLRSLKEIHLL------------ 689
                   |...|:.:.|        |.:...:...||.|  |..|..|.:.|.
 Frog   681 ELLKDHGLLEENVAQRGDRNSRQRQHKERKELHQLKRQHERVEKRKRKVLKLQDEGAGSSSDGEE 745

  Fly   690 ----------------VQELRVRCTH-LGLIPFPVNPNQMMDDREKAIMLKVIIAGAFYPNY-FT 736
                            :|:::.:..| :..:....:..|.:..:|.: :||:|:....||.. ..
 Frog   746 QYHTEKHRKDRKDSIDIQDVKFKLRHNIHELHASSSTGQDLSSQEVS-LLKLIVCHGLYPQLGVP 809

  Fly   737 RSKESCADTDRNIYQT 752
            .|..||......::.|
 Frog   810 DSFNSCRKDSDQVFHT 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	187/672 (28%)
		DEXHc_TDRD9	115..295	CDD:350746	74/179 (41%)
		TUDOR	892..1016	CDD:425754
dhx34	NP_001121459.1	HrpA	152..>616	CDD:441249	165/510 (32%)
		OB_NTP_bind	794..903	CDD:400182	9/32 (28%)