Protein Alignment spn-E and dhx35

DIOPT Version :10

• Sequence 1: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Sequence 2: XP_073795786.1
• Gene: dhx35 / 100037310
• ZFINID: ZDB-GENE-070410-11
• Length: 699
• Species: Danio rerio
• Alignment Length: 729
• Identity: 195/729 - (26%)
• Similarity: 327/729 - (44%)
• Gaps: 141/729 - (19%)

  Fly   113 KNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKS-GKYCNIVVTQPRRIAAI 176
            :.|.::..|..||..:.:...|:|.||||.||:||:|||:|:..:.: ||.  |.||||||:||.
Zfish    50 QRLPVFKHRNNILYLVESFQTVVIVGETGSGKSTQIPQYLLEAGWAAEGKV--IGVTQPRRVAAT 112

  Fly   177 SIANRVCQEREWQQNTVCSFQVGLH-RPNSLED---TRLLYCTTGVLLNNLINNKTLTHYTHIVL 237
            |:|.||.:||    ......:||.. |.:...|   ||:.:.|.|:|:..::::..|..|:.::|
Zfish   113 SVATRVAEER----GAFLGHEVGYTIRFDDCSDPHATRIKFLTDGMLVREMMSDPLLKKYSVLIL 173

  Fly   238 DEVHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNSIPPV-----ITTNH 297
            ||.|||....|..:.:::::| ...|.:::|:.|||:|||:..|:|....|....     |.|..
Zfish   174 DEAHERTLYTDIAIGLLKKIL-KKRRDLRLIVASATLDAKKFQDFFNLNESGDASKDTCGILTVE 237

  Fly   298 RRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAIQSRQSYDEA 362
            .|...::.||.              ...||:..|    |.|:.::.|...|           |:
Zfish   238 GRTFPVDIFYT--------------VSPVPDYVK----ATVETVLKIHETE-----------DD- 272

  Fly   363 LRYGAVLIFLPGIYEIDTMAENLTCMLENDPNI--------KVSIVRCFSLMTPENQRDVFNPPP 419
               |.||.||.|..|:    |.:..:|:.....        .:.::..::.:....|..||....
Zfish   273 ---GDVLAFLTGQEEV----EKVVSLLQEQARTLSRYGMKKHLCVLPMYAGLPYNEQMRVFERMA 330

  Fly   420 PGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRL 484
            |..||:::.|||||:|||:..|.:|||....|::..:..::..||.:|..|||:..|||||.||.
Zfish   331 PTVRKVVVATNIAETSITINGVVFVIDCAFVKIRAYNPRTAIESLIVTPISKASACQRAGRAGRN 395

  Fly   485 RSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALA-LSPPNLSDIHN 548
            |:|:.:|:..:..::: :||..:|||.|..|...:|:.|.|.:.:   :|..: ||||....:..
Zfish   396 RAGKCFRLYTEEDFEK-LPESTVPEMQRSNLAPVILQLKALGIDN---VLRFSFLSPPPAQSMVQ 456

  Fly   549 TILLLKEVGAL----YLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIII 609
            .:.||..:|.|    .||     ||:       |..|:..||....:::::....|...:|.:.|
Zfish   457 ALELLFALGGLDQYGRLT-----DPM-------GVRMAEFPLSPMFAKMLLESGNFGCSKEIVTI 509

  Fly   610 AAGLSTPGLFA--HEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQESAIRW 672
            ||.:....:|.  |...:|...:    |..|:...|.        :||.||:.|.....:.:.:|
Zfish   510 AAMMQIQNIFVAPHNQRKSAARE----HRKFAVAEGD--------HLTMLNVYEAFIKHQKSSQW 562

  Fly   673 AKRFHVSLRSLKEIHLLVQELRVRCTHLGLIPFPVNPNQMMDDREKAIMLKVIIAGAFYPN---- 733
            .:...::.:.|.....:.::||    || |..|.|.......|.:  ::|:.|::| |:.|
Zfish   563 CQDHFLNYKGLLRATAVREQLR----HL-LNKFKVPRTSSEGDPD--VILRCIVSG-FFANAARM 619

  Fly   734 YFTRSKESCADTDRNIY----QTISGHDPCRTVYFTN---------------------------F 767
            :.:.|..:..| ||.:|    ..:.|..|.:.|.|..                           :
Zfish   620 HHSGSYRTLRD-DRELYIHPDSVLYGEKPPKWVVFNEVVQTSKYYMRDVTAVESSWLVELAPHFY 683

  Fly   768 KPAYMGELYTRRIK 781
            |.|..|.|.::|.|
Zfish   684 KQAKHGSLSSKRAK 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	169/607 (28%)
		DEXHc_TDRD9	115..295	CDD:350746	66/189 (35%)
		TUDOR	892..1016	CDD:425754
dhx35	XP_073795786.1	None