DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arpc3A and ARPC3

DIOPT Version :9

Sequence 1:	NP_650498.3	Gene:	Arpc3A / 41917	FlyBaseID:	FBgn0038369	Length:	177	Species:	Drosophila melanogaster
Sequence 2:	NP_001265485.1	Gene:	ARPC3 / 10094	HGNCID:	706	Length:	178	Species:	Homo sapiens

Alignment Length:	178	Identity:	106/178 - (59%)
Similarity:	144/178 - (80%)	Gaps:	1/178 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPAYHSQIKEV-RQQVGNMAILPLRTQVRGPAPSANIESDIIDESLYYFKANVFFRTYEIKSDVD 64
            ||||||.:.:. .:.:||||:||:|:|.:||||....::||:||::|||||||||:.||||::.|
Human     1 MPAYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDTDIVDEAIYYFKANVFFKNYEIKNEAD 65

  Fly    65 RVLIYVTLYITECLKKLNRSTSKAQGQQDMYSLAISKFDIPGDAGFPLNAVYAKPQTAQDADLMR 129
            |.|||:||||:||||||.:..||:||:::||:|.|:.|.|||:.||||||:||||...|:.::||
Human    66 RTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFPLNAIYAKPANKQEDEVMR 130

  Fly   130 QYLLQLRHETGNRVLEKVFNTEDGKPNKWWTCFAKKKFMEKSLAGPGQ 177
            .||.|||.|||.|:.||||:.::.||:||||||.|::||.|||:||||
Human   131 AYLQQLRQETGLRLCEKVFDPQNDKPSKWWTCFVKRQFMNKSLSGPGQ 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arpc3A	NP_650498.3	P21-Arc	1..172	CDD:397948	100/171 (58%)
ARPC3	NP_001265485.1	P21-Arc	1..173	CDD:397948	100/171 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160523
Domainoid	1	1.000	229	1.000	Domainoid score	I2475
eggNOG	1	0.900	-	-		E1_KOG3155
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4178
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3372
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54322
OrthoDB	1	1.010	-	-		D1451115at2759
OrthoFinder	1	1.000	-	-		FOG0004013
OrthoInspector	1	1.000	-	-		otm40583
orthoMCL	1	0.900	-	-		OOG6_102731
Panther	1	1.100	-	-	LDO	PTHR12391
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2769
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770