DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4576 and Oacyl

DIOPT Version :9

Sequence 1:	NP_650495.1	Gene:	CG4576 / 41914	FlyBaseID:	FBgn0038366	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	XP_036017063.1	Gene:	Oacyl / 319888	MGIID:	2442915	Length:	717	Species:	Mus musculus

Alignment Length:	722	Identity:	159/722 - (22%)
Similarity:	273/722 - (37%)	Gaps:	183/722 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LDDYDRCLQELNGQAS---TYCFVR-AEVQPDESV-------AAWRAIAEISQYDRHHF-----D 88
            |..|..||...:.:.|   .||.:. .:...|.||       .|...:..:||.|:..|     .
Mouse    69 LGSYSECLSTRSPKGSFRGQYCKLHILQDGTDYSVGVCVPDSCAEEDVTMMSQLDKPSFFDLYTH 133

  Fly    89 HRQLYFGLCLRECEASLAGLNKSELEALQAGLLSENAKVNVYLDLFSMEANNRQRHQRLTNACLN 153
            |..|.....:..|...:: |....|:......|..:      |.||:.::         :::|
Mouse   134 HASLDCRHTMSPCPTKIS-LFLGTLKFRNTSFLEPS------LSLFTKDS---------SSSC-- 180

  Fly   154 WRLQRRGFGVLAKSVVEYCDEAGHQVEDDAWNLTFYGILGTLLVLACLGSLV----DLHLKRSRH 214
                         .||..|.......:..|....|..:||  |||...|::.    |..|.
Mouse   181 -------------EVVARCAAGAMSPDMFASVCLFITLLG--LVLPVAGTVYMVARDWGLD---- 226

  Fly   215 DKMLKERDHYKTPPKSTAQQVLLTFSVARNWYRLNQE----PSGKIGRELRF-------LDCF-- 266
               |:....:.|||.|.....|......|...|.:.:    |.|...|..||       |.||
Mouse   227 ---LRTSSVHGTPPTSCESLPLRNMESNRQRSRASCQVQLPPPGAPSRGRRFLGAVDEVLQCFSW 288

  Fly   267 -----------------------KFFAMFMVIFAHTN----WVIYESAIS----NPQDPERLLHT 300
                                   :..::..||..||:    |:..::.:.    .|::| ..|::
Mouse   289 QKNMPAICSPELPGGTCRTLNGIRVLSLLWVISGHTSQMTAWLSLDNVLEWKSRVPENP-LYLYS 352

  Fly   301 AAGTLLVSGSLITVTFFVISGLLLTINWLAVSRSLESKKDTWSFGQYALLFVKFNIFRYIRLTVP 365
            .:|...:.    ..|||:|||      ||:....|:..::| |.|....:.:::.:.|:.||.:.
Mouse   353 RSGPFYLG----VDTFFLISG------WLSARSFLKMHQNT-STGITPKVILRYFLKRFTRLQLL 406

  Fly   366 YAF-VLLMSGVYFENAGGPLWRHIFEREQLACRRNWWTNLLYVNNFVRTDERCLLQGWYLAADTH 429
            :.: |.|:.|.:.....||:| .:.:.....||..||||||.:|||:.....|....||||:| .
Mouse   407 HMYSVCLLVGFFSFVPWGPVW-EVAQFHWDNCREVWWTNLLLLNNFLSVQNACNGWTWYLASD-F 469

  Fly   430 SFVLSLVLLMLGHRFVRWSKQLYAGILGLFVVVP------MVLTYAMNYYPIFVPTPQTQKDSFI 488
            .|.|:..|:...|   ..||:::..:.||..:..      :.|.|.:   |:..|...::..:.:
Mouse   470 QFHLTTPLIFFVH---GKSKRVFVLLGGLLFLASSTATTLLTLAYKL---PVASPAAASEHGTVL 528

  Fly   489 GDRQFTEFYTSSFMNFGSYFCGVLAALVYDQLALKQYKLRELKSFQLLWFTLIPVGILWLFSAHP 553
               .|:|:||..:...|.:..|:..::...    ..:....||       |.:...:.|.:|...
Mouse   529 ---YFSEYYTKPYCRCGPFLVGLFLSMFMH----SDHPTDILK-------TTVQAMLGWTWSLLT 579

  Fly   554 IFQHY---YV----TP-SAIWGALYAGLQRNIWGFGLGIFIVGMASKVGWIFRKFCCL-----PI 605
            :|...   ||    :| |::..|:|..|.|.:|           |:.|||:.  |.|.     |:
Mouse   580 LFAVVALAYVLDDTSPTSSVAAAIYQALHRTLW-----------AAAVGWVI--FACQEGYGGPV 631

  Fly   606 FRIL--------GRLTYGAFIVHLLVARIVLATVREPI--YFGTGMMFAFIFFTVTVSYLCSFLL 660
            .|:|        ..::|..::||.:|. |:...::|.:  |..|.|::.| |....:::|...:|
Mouse   632 KRMLSWGIWSLPASISYACYLVHPIVI-ILYNGLQETLIHYTDTNMLYLF-FGHCVLTFLGGLVL 694

  Fly   661 AIFLELP 667
            .:|:|.|
Mouse   695 TLFIERP 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4576	NP_650495.1	Acyl_transf_3	260..657	CDD:280013	106/466 (23%)
CG4576	NP_650495.1	OafA	303..668	CDD:224748	97/395 (25%)
Oacyl	XP_036017063.1	NRF	44..122	CDD:214781	12/52 (23%)
Oacyl	XP_036017063.1	OafA	308..710	CDD:224748	105/443 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810