DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4576 and oac-54

DIOPT Version :9

Sequence 1:	NP_650495.1	Gene:	CG4576 / 41914	FlyBaseID:	FBgn0038366	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_495953.3	Gene:	oac-54 / 189275	WormBaseID:	WBGene00012323	Length:	477	Species:	Caenorhabditis elegans

Alignment Length:	487	Identity:	106/487 - (21%)
Similarity:	199/487 - (40%)	Gaps:	105/487 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 TAQQVLLTFSVARNWYRLNQEPSGKIGRELRFLDCFKFFAMFMVIFAHT-------------NWV 282
            |:..:|...|:.|:...|....|.|    |.|:|.|:..|:..|:..||             :..
Worm    42 TSNNILSALSLKRSIKELLTGRSSK----LDFIDIFRCVAIIWVMINHTGGRGRIDVLEGLSSAE 102

  Fly   283 IYESAISNPQDPERLLHTAAGTLLVSGSLITVTFFVISGLLLTINWLAVSRSLESKKDTWSFGQY 347
            .:.||:.|        |...|.|:.:.:|....|.|:||||...:||        :|....|.|:
Worm   103 AFTSAMHN--------HPIFGALMGNSALGVEIFLVLSGLLAARSWL--------RKADEPFFQH 151

  Fly   348 ALLFVKFNIFRYIRLTVPYAFVLLMSGVYFENAGGPLWRHIFER----EQLACRRNWWTNLLYVN 408
            .:.|:   |.|.:|| .|..|:.:...:      ||:.:....|    ...:|  .:| |::.:.
Worm   152 WITFI---IRRILRL-APVMFIFIYIAI------GPIMKKFLPRFTFSSVSSC--GFW-NIISLF 203

  Fly   409 NF---VRTDERCLLQGWYLAADTHSFVLSLVLLMLGHRFVRWSKQLYAGIL--------GLFVVV 462
            .|   ::|...|:...|||..|...::::.:.|.|.|      |....||:        .:|:..
Worm   204 TFTGNLQTSPTCMTYIWYLGLDMQLYMVASIFLSLLH------KSPKRGIVLTITTIIASMFIRA 262

  Fly   463 PMVLTY-AMNYYPI---FVPTPQTQKDSFIGDRQFTE---FYTSSFMNFGSYFCGVLAALVYDQL 520
            .....| ..|:..:   |:..|  .:|..:..|.:..   .|:..:...|.:..|:|  |.|..:
Worm   263 GYCTAYGTCNHSDVDVAFITKP--GQDPAVLARSYEGLWLIYSRPYTKCGPFLIGLL--LGYTTV 323

  Fly   521 ALKQYKLRELKSFQLLWFTLIPVGILWLFSAHPIFQHYYVTPSA---IWGALYAGLQRNIWGFGL 582
            :.| |.:.:..: ::::.:.:.|.|..:::..|    .|..|:|   ::..:|..:.|:::...:
Worm   324 SSK-YIMSDALT-KIVFRSSLFVAIATIYAILP----EYWNPNAGNTLYNTVYTAVFRSVFAMAI 382

  Fly   583 GIFIVGMASKVGWIFRKFCCLP--IFRILGRLTYGAFIVHLLVARI-----VLATVREPIYFGTG 640
            ...|..|      .|::.|...  :|.|||:||:..:::|:.|...     .|.|...||
Worm   383 SGMIAAM------YFKEGCSSTPLVFSILGKLTFNTYLLHMPVVYTFNWLSFLQTATSPI----- 436

  Fly   641 MMFAFIFFTVTVSYLCSFLLAIFLELPVSSFL 672
            .:|..|.|...:||:.:....:|:|.|:.:.:
Worm   437 ELFLVIPFIAMLSYVAALFFYLFVEAPMGNLM 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4576	NP_650495.1	Acyl_transf_3	260..657	CDD:280013	96/441 (22%)
CG4576	NP_650495.1	OafA	303..668	CDD:224748	86/396 (22%)
oac-54	NP_495953.3	OafA	64..473	CDD:224748	101/465 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161179
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700