DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4576 and oac-32

DIOPT Version :9

Sequence 1:	NP_650495.1	Gene:	CG4576 / 41914	FlyBaseID:	FBgn0038366	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_001300114.1	Gene:	oac-32 / 186125	WormBaseID:	WBGene00018708	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	680	Identity:	163/680 - (23%)
Similarity:	279/680 - (41%)	Gaps:	150/680 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EMPPLYDLDDYDRCLQELNGQA--STYCFVRAEVQPDESVAAWRAIAEISQYDRHHFDHRQLYFG 95
            |:..||| ..|..| |.::|:.  ..||::.  :.|.::|::
Worm    97 ELKTLYD-GSYQEC-QRVSGKKYDVNYCYLL--LTPGKNVSS----------------------- 134

  Fly    96 LCLRECEASLAGLNKSELEALQAGLLSENAKVNVYLDLFSMEANNRQRHQRLTNACLNWRLQRRG 160
                 |..|.:....|:|....|..|.::......:|:|     |.......| ||
Worm   135 -----CAPSNSKSLYSQLPLRIAVCLPDSCNHQDMIDIF-----NELSPYPFT-AC--------- 179

  Fly   161 FGVLAKSVVEYCDEAGHQVEDDA--WNLTFYGILGTLLVLACLGSLVDLHLKRSRHDKMLKERDH 223
                    ..||.:  ::|:.|.  |..:.:.|:  ::|:|.:.|:||          .::|..:
Worm   180 --------SAYCTK--NEVKKDTPFWGFSIFLIV--MVVIAAIASIVD----------YVRETVY 222

  Fly   224 YKTPPK--STAQQVLLTFSVARN---WYRLNQEPSGKIGRELRFLDCFKFFAMFMVIFAHTNWVI 283
            ..:..|  :|..::|||||:..|   ...:.::.||.|    :.|||.:..:|..|:..|:  .:
Worm   223 GLSSQKENNTFFKILLTFSLWTNAELLLSVKEQKSGFI----KSLDCIRLLSMCWVVTGHS--FL 281

  Fly   284 YESAISNPQDPERLLHTAAGTLLVSGSLITV-TFFVISGLLLTINWLAVSRSLESKKDTWSFGQY 347
            | ..:::..:|.....|.....|:..:.::| ||||:||::  :.:|.....|..|..|     .
Worm   282 Y-LILADTLEPVLDFPTYFWNHLLLNAFVSVDTFFVLSGIV--VAYLFFKTKLTKKTIT-----S 338

  Fly   348 ALLFVKFNIFRYIRLTVPYAFVLLMSGVYFENAGGPLWRHIFEREQL--------ACRRNWWTNL 404
            .:.::.|.:.||:|||.|   |:|..|  |.....|..:..|...:|        ||:..||.||
Worm   339 PMTWILFYVHRYLRLTPP---VMLFIG--FFTVYTPYIQGAFSASELNQMAPQAAACKTLWWQNL 398

  Fly   405 LYVNNF---VRTDERCLLQGWYLAADTHSFVLS-LVLLMLGHRFVRWSKQLYAGILGLFVVVPMV 465
            ||:|||   ...:..|....||||.||..:::: :||:.|...|...:..:.||.:|     .::
Worm   399 LYINNFDDGNSQNSTCYGITWYLAVDTQLYLVAPIVLVALYFSFAAGTAIIVAGCVG-----SII 458

  Fly   466 LTYAMNYYPIF-VPTPQTQKDSFIGDRQFTEF----YTSSFMNFGSYFCGVLAALVYDQLALKQY 525
            .||.:  :.:: ||.      ..||:...|:|    |:..::....|..|:|...:     |..|
Worm   459 TTYIL--FGVYNVPA------DIIGNGDQTKFFNIAYSKPWIRCPPYLVGLLTGYL-----LATY 510

  Fly   526 KLRELKSFQLL----WFTLIPVGILWLFSAHPIFQHYYVTPSAIWGALYAGLQRNIWGFGLGIF- 585
            ..|:::....|    |.|...:....||:.      |.....|.|.........|....|.|:|
Worm   511 GSRKIRLNWALAIAGWITAFVIAGFCLFAT------YDYDKGAHWSTFTRATFYNFHRLGWGVFV 569

  Fly   586 --IVGMASKVGW--IFRKFCCLPIFRILGRLTYGAFIVHLLVARIVLATVREPIYFGTGMMFAFI 646
              :|| |:.:||  ...||...||::..|||:|.|:|||.:|....|.......|.....:|.:|
Worm   570 CWVVG-ANHMGWGGPIDKFMSHPIWQPFGRLSYCAYIVHWMVLYYYLNVGGVLHYSSAWQVFTYI 633

  Fly   647 FFTVT-VSYLCSFLLAIFLELPVSSFLKLM 675
            ....| :||:.:|..:...|:|:....|::
Worm   634 AIPATLLSYVLAFFWSCLFEVPILKLEKML 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4576	NP_650495.1	Acyl_transf_3	260..657	CDD:280013	112/424 (26%)
CG4576	NP_650495.1	OafA	303..668	CDD:224748	105/392 (27%)
oac-32	NP_001300114.1	NRF	77..185	CDD:214781	26/142 (18%)
oac-32	NP_001300114.1	OafA	254..659	CDD:224748	118/448 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161187
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740