DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4576 and oac-3

DIOPT Version :9

Sequence 1:	NP_650495.1	Gene:	CG4576 / 41914	FlyBaseID:	FBgn0038366	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_506446.2	Gene:	oac-3 / 182290	WormBaseID:	WBGene00007361	Length:	691	Species:	Caenorhabditis elegans

Alignment Length:	703	Identity:	161/703 - (22%)
Similarity:	275/703 - (39%)	Gaps:	156/703 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 YCFVRAEVQPDESVAAWRAIAEISQYDRHHFDHRQLYFGLCL--RECEASLAGLNKSELEALQ-- 117
            |..|..|...|  :..|  |:.|.|:.....|        ||  :.|.||:..:.|..:.|:|
Worm    40 YSHVTPECTKD--MKTW--ISSIEQFTAASSD--------CLFFKNCTASILNILKDNIYAIQQY 92

  Fly   118 --------AGLLSENAKVNVYLDLFSMEANNRQRHQRLTNACL------------NWRLQRRGFG 162
                    ||||    :|::..|....|.:.....:..||.|.            ...:|..|..
Worm    93 DAFAKIPSAGLL----EVSLVFDGSYQECHRISGVKYETNYCYVLLVPGRNANCSGGSIQNAGTS 153

  Fly   163 VLAKSVV---------------------------EYCDEAGHQVEDDAWNLTFYGILGTLLVL-- 198
            |..:..|                           .:|.:  ..|..|:   .|:|....:.|:
Worm   154 VAFRRAVCMPKSCASSDTVDLYNQLSALPLTACATFCSQ--RDVPKDS---AFWGFSAFMFVIVS 213

  Fly   199 -ACLGSLVDLHLKRSRHDKMLKERDHYKTPPKSTAQQVLLTFSV---ARNWYRLNQEPSGKIGRE 259
             ..|.:.|| :|:.|.:|...|..:     ..::..::|.:||.   |.....::.:|:    ..
Worm   214 TVILATTVD-YLRESVYDISSKSIE-----KSASLYRLLYSFSFWTNASTILNVSSQPA----TH 268

  Fly   260 LRFLDCFKFFAMFMVIFAH-TNWVIYESAISNPQDPERLLHTAAGTLLVSGSLITV-TFFVISGL 322
            ::.|||.:..:|..|:..| .|:..:...:.    |.:.............::.:| |||::||:
Worm   269 IKCLDCIRGLSMAWVLSGHMLNYFAFADTLM----PIKSFANYFADYFFMNAVFSVDTFFLVSGI 329

  Fly   323 LLTINWLAVSRSLESKKD--TWSFGQYALLFVKFNIFRYIRLTVPYAFVLLMSGVYFENAGGPLW 385
            .:..::..:..:.::.|.  ||         :.|.:.||:|||.||...:....||.....|||.
Worm   330 TVAYSFFRLKPTTKTLKSPATW---------ILFYVHRYVRLTPPYIIFIGFYAVYALYIQGPLA 385

  Fly   386 RHIFEREQL---ACRRNWWTNLLYVNNFVRTDERCLLQGWYLAADTHSFVLSLVLLMLGHRFVRW 447
            ..:|....|   ||:.:||.||:|:|||...:..|....||||.||..::::.:||:.    :.|
Worm   386 ASLFNFTVLQVEACKASWWRNLIYINNFDNGENPCYGPSWYLAVDTQLYLVAPILLVA----LTW 446

  Fly   448 SKQLYAGILGLFV-----VVPMVLTYAMNYYPIFVPTPQTQKDSFIGDR--QFTEF-YTSSFMNF 504
            :.     |.||.|     :..|::.:.: |....:|.     |||..|.  :|..: |...:...
Worm   447 TP-----IAGLVVSMVGCIGSMIIVFIL-YQKFDMPA-----DSFNADSSGKFNFYVYQKPWTRC 500

  Fly   505 GSYFCGVLAALVYDQLALKQYKLRELKSFQLLWFTLIP----VGILWLFSAHPI----FQHYYVT 561
            ..|..|:|......:.|....||..:|.       |||    ||:::......|    ..|:
Worm   501 PPYLVGILGGYFLSRFATSPVKLSFVKK-------LIPMLLAVGLIFACLTANIGYDQGDHW--- 555

  Fly   562 PSAIWGALYAGLQRNIWGFGLGIFIVGMASKVGWI--FRKFCCLPIFRILGRLTYGAFIVHLLVA 624
             |:...|.|....|..|  .|.:..:.::...||.  ...|...||::.||||:|.|:||||:|.
Worm   556 -SSWTKATYYNFSRFFW--ALSVLWIILSCHYGWAGPIGNFMSHPIWQPLGRLSYSAYIVHLMVV 617

  Fly   625 RIVLATVREPIYF-GTGMMFAFIFFTVTV-SYLCSFLLAIFLELPVSSFLKLM 675
            ...|....:|::| .|..::.:.....|: :|:.:|..:...|:||....|.:
Worm   618 YYFLNVGDKPLHFVSTWQVYVYYILPATILTYIFAFFWSCLFEIPVVKLEKFL 670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4576	NP_650495.1	Acyl_transf_3	260..657	CDD:280013	107/423 (25%)
CG4576	NP_650495.1	OafA	303..668	CDD:224748	101/390 (26%)
oac-3	NP_506446.2	NRF	85..191	CDD:214781	16/109 (15%)
oac-3	NP_506446.2	Acyl_transf_3	269..653	CDD:376607	107/424 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810