Protein Alignment alpha-Man-IIb and man2c1

DIOPT Version :10

• Sequence 1: NP_650494.2
• Gene: alpha-Man-IIb / 41913
• FlyBaseID: FBgn0026616
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: XP_009296368.1
• Gene: man2c1 / 569595
• ZFINID: ZDB-GENE-101103-4
• Length: 1034
• Species: Danio rerio
• Alignment Length: 747
• Identity: 137/747 - (18%)
• Similarity: 254/747 - (34%)
• Gaps: 178/747 - (23%)

  Fly   150 RGFEERFDAQKKDKQRPPLKIIVVPHSHNDPGWLKTFTNYFQSDSRQILNLLVTKMQEYTDMTFI 214
            |...::|.|||..:.:.  .:..:.|.|.|..||..:....:..:|..:. ::..|::..:..|.
Zfish   245 RSLAQKFFAQKNGESQH--VVHAMGHCHIDSAWLWPYEETIRKCARSWVT-VIRLMEKNPEFVFT 306

  Fly   215 WSEISFLQLWWDQAHPTKQRALKRLIDAGRIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLKNN 279
            .|:....| |....:|.....:|..|..|:.....|.||..|........|:.|.:.|..:.|:.
Zfish   307 CSQAQQFQ-WVKSWYPGLFSEIKHFIQKGQFIPVGGTWVEMDGNLPSGESMVRQFLHGQNFFKDE 370

  Fly   280 LNVTPKVGWSIDPFGHGSTVPYLLSGANFEGTIIQRIHYAWKQWFARQQSGDFIWKPYWRSRKDK 344
            .....|..|..|.||:.:.:|.::.|......|.|::.:.....|..   ..|.|         :
Zfish   371 FGNYCKEFWLPDTFGYSAQLPQIMKGCGISRFITQKLSWNLINTFPH---NTFFW---------E 423

  Fly   345 DSEAGSLLTHNMPFDIYSIKGSCGPHPFICLNFDFRKIPGEYTEYSVKAQFITDDNLESKAQLLL 409
            ..:..::|||..|.:.|.:||                        .|:....|..|.:.|.:.
Zfish   424 GIDGTAVLTHFPPGNSYEMKG------------------------KVEDLINTVKNNKDKGRA-- 462

  Fly   410 EQYARTASLFPHNVALIPVGDDFRYNKDREVDQQYQNYKKLIDHIMANRRLYNAD----IRFGTP 470
                      .|:..|...||.........:|:.:              |:.:.|    ::..||
Zfish   463 ----------NHSALLFGFGDGGGGPTQLMLDRLH--------------RVKDTDCLPKVQMSTP 503

  Fly   471 SDYFEAIKERMKDHTPGFPTFKGDFFVYSDIFSEGRPAYWSGYFTTRPFYKLLSSELEHQLRSAE 535
            ...|    ..::..:.....:.|:.|:          ...:|.:||:...|:.:.:.|..|...|
Zfish   504 DVLF----SHLESDSSLLCRWVGELFL----------ELHNGTYTTQAKIKMKNRQCETLLHDVE 554

  Fly   536 IVFTLAYNTARQAKRENAIKIYEKNYELIINARRNLGLFQHHDAITGTSKAAVMRDYAMRLFEST 600
            :...||. :.:.:.:..|.::.|....|::|        |.||.|.|:....|:.| |::.::..
Zfish   555 VASCLAL-SKKDSFKYPACRLQELWRLLLLN--------QFHDVIPGSCIGMVVED-ALQYYDEI 609

  Fly   601 QNMVK--MQESCLELLLQKGQPRHHGFLLS--EFERDNFNKLPRKMPIQMANGDEST-------P 654
            .....  :.::|..|   ...|.:...:|:  .:||.....||.|        |..|       |
Zfish   610 HTTASRLLLDACKSL---PSSPDNGIAVLNTLSWERTEVISLPMK--------DTETRLALVRVP 663

  Fly   655 TVPAGEGGAGGSSSSGSV------GSFVLYNSLAQKRLE----VVTLRVQHPNVKIVNDKGVELN 709
            :|..........|:...:      |:.::.|.|.:..::    :::|.:...|.:.::: |...|
Zfish   664 SVGVAHVKETAESAESVIATMMVNGTIIMENGLLKATIDHLGRLMSLLLIQTNRETISE-GCFGN 727

  Fly   710 HIQIN-------PVWNITDTYEQ------------------GLGTSVSGTVGRIRTSTRQFEVMF 749
            ...:.       ..|::.|.:.|                  |:..|||.::.....||.|.|::.
Zfish   728 QFALFDDVPLYWDAWDVMDYHLQTRKPVIEVIEPAKVLKSGGIQASVSFSLRINGKSTIQQEIVL 792

  Fly   750 VAELEPLSLSTYRVQVDEVNFKRNIATIYCDDCTESQPASVSPPE---EIE----SSPT------ 801
            .|....:...|:.|..:...|.:           ...|..|..||   ||:    ..||
Zfish   793 DACCPYIKFKTHVVWEEAHKFLK-----------VEFPVQVRSPEATYEIQFGHLQRPTHRNTSW 846

  Fly   802 --SVFEARGKPAGDIQLENPHMRLLFDEKSGF 831
              :.||..|....|:......:.||.|.|.|:
Zfish   847 DWARFEVWGHKWADLSEHGFGVALLNDSKYGY 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIb	NP_650494.2	PLN02701	148..1246	CDD:178304	137/747 (18%)
man2c1	XP_009296368.1	MngB	256..1031	CDD:440152	132/736 (18%)