Protein Alignment alpha-Man-IIb and man2b1

DIOPT Version :9

• Sequence 1: NP_001262614.1
• Gene: alpha-Man-IIb / 41913
• FlyBaseID: FBgn0026616
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: XP_005169420.1
• Gene: man2b1 / 541519
• ZFINID: ZDB-GENE-050327-52
• Length: 984
• Species: Danio rerio
• Alignment Length: 1149
• Identity: 287/1149 - (24%)
• Similarity: 462/1149 - (40%)
• Gaps: 280/1149 - (24%)

  Fly   168 LKIIVVPHSHNDPGWLKTFTNYFQSDS--------RQILNLLVTKMQEYTDMTFIWSEISFLQLW 224
            |.:.:|||:|:|.|||||...||..|.        :.||:.::.::|:.....||:.|.:|...|
Zfish    44 LNVHLVPHTHDDVGWLKTVDQYFYGDRNNIQHAGVQYILDSVIDQLQKDPARRFIYVETAFFYRW 108

  Fly   225 WDQAHPTKQRALKRLIDAGRIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLKNNLNV--TPKVG 287
            |.|.:...:|.:.:|::.||:|...|||.|:|||..|...::||:..|.::|.:....  .|:|.
Zfish   109 WRQQNQNTRRIVTQLVNEGRLEFINGGWCMSDEATTHYSAVIDQMTLGLRFLNDTFGECGRPRVA 173

  Fly   288 WSIDPFGHGSTVPYLLSGANFEGTIIQRIHYAWKQWFARQQSGDFIWKPYWRSRKDKDSEAGSLL 352
            |.||||||......:.:...::|....|:.|..|....:.:..:.:    ||:.:........|.
Zfish   174 WHIDPFGHAREHASIFAQMGYDGFFFGRLDYQDKDRRMKTKEMEML----WRASESLTPPIADLF 234

  Fly   353 THNMPFDIYSIKGSCGPHPFICLNFDFRKIPGEYTEYSVKAQFITDDNLESKAQLLLEQYARTAS 417
            |..:|......:|.|....  |.:...|..|.           :.|.|::...|..|....:.|.
Zfish   235 TGVLPNGYNPPEGFCWDQS--CDDAPIRDDPD-----------LEDYNVDEIVQKFLNASHKQAD 286

  Fly   418 LFPHNVALIPVGDDFRYNKDREVDQQYQNYKKLIDHIMA-NRRLYNADIRFGTPSDYFEAIKERM 481
            .:..|..::.:|.||:|   ...:..|:|..|||.::.| ..:....::.:.|||.|.:.:  .:
Zfish   287 YYKTNHIIMTMGSDFQY---ENANLWYKNMDKLIKYVNALQAKGSKLNVLYSTPSCYLQEL--NL 346

  Fly   482 KDHTPGFPTFKGDFFVYSDIFSEGRPAYWSGYFTTRPFYKLLSSELEHQLRSAEIVFTLAYNTAR 546
            .:.|  :|....|||.|:|...:    :|:||||:||..||.......:|::...:..|...|:.
Zfish   347 ANFT--WPMKTDDFFPYADDAHD----FWTGYFTSRPALKLYERLSNSRLQTCNQLEVLGGPTST 405

  Fly   547 QAKRENAIKIYEKNYELIINARRNLGLFQHHDAITGTSKAAVMRDYAMRLFESTQNMVKMQESCL 611
            ..      ...|.:.:.:   ||.:|:.|||||::||.|..|..|||.||.....:...:..:.|
Zfish   406 SG------PFGEGDSDTM---RRAMGVAQHHDAVSGTEKQHVANDYARRLATGWAHCEVLVSNSL 461

  Fly   612 ELLLQKGQPRHHGFLLSEFERDNFNKLPRKMPIQMANGDESTPTVPAGEGGAGGSSSSGSVGSFV 676
            .:|.....||..      .|..|.:..|                          .:.|....|..
Zfish   462 AVLSGSEAPRVF------CENLNISVCP--------------------------LTESSHKFSMN 494

  Fly   677 LYNSLAQKRLEVVTLR--VQHPNVKIVNDKGVELNHIQINPVWNITDTYEQGLGTSVSGTVGRIR 739
            :||.|.:      |:|  |:.|    ||           ..|:|:||...:.:.:.|. .:.:.|
Zfish   495 VYNPLGR------TVRWPVRLP----VN-----------GSVYNVTDANGKAVDSEVI-PLSKSR 537

  Fly   740 TSTRQ------FEVMFVAELEPLSLSTYRVQVDEVNFKRNIATIYCDDCTESQPASVSPPEEIES 798
            ...||      .|::|..|..||..|||.:.:                 .:.||
Zfish   538 KEVRQNRGFAKSELVFQVEAPPLGYSTYIISM-----------------VQDQP----------- 574

  Fly   799 SPTSVFEARGKPAGDIQLENPHMRLLFDEKSGFLKTITRKNQKKELLKPLQCNIKFAAYRSA--- 860
             |.|    |.|.|....::|..:::.||..:|.|.::|    ..|..:.::....|..|.::
Zfish   575 -PVS----RSKNAVPSSIQNKFLKVTFDSTTGLLSSLT----NLETQQTIRLTQNFFWYNASAGN 630

  Fly   861 --QFH--SGAYLFKTDPEQSE-------AEKEVLEGYTDMRIIITSGPIASDVTVIYGPFLAHTV 914
              :.|  ||||:|:  |..|:       ||.:.:..|..::          :||..:.|:::..|
Zfish   631 NKESHQPSGAYIFR--PNSSDPFIISKTAEIQAVSLYNSVQ----------EVTQRFSPWVSQVV 683

  Fly   915 RIFNTRTHLDAAIYVENDIDFEPPPKNRETELFMRFVTNIDNIAQAPMQRDPLKEPVDAATMPEL 979
            |::..|..|        ::::...|...|..|....:|.:|...|:.
Zfish   684 RLYEDRREL--------ELEWTVGPVPVEDGLGKEVITRLDTDIQSS------------------ 722

  Fly   980 PVFYSDQNGFQYHERIK-----------VPAIGIEGNYFPITSGAFIQDSRLRLTLLTTHAQGAA 1033
            ..||:|.||.:..||.|           .|   |.|||:||.|.|:|:|.:.:||::|..:|||:
Zfish   723 GYFYTDSNGREVLERRKDYRPTWDLKQTEP---IAGNYYPINSRAYIKDDKRQLTVVTDRSQGAS 784

  Fly  1034 SYEPGQLEVMLDRRTLYDDYRGMGEGVVD------SRLTRHKFWLLVEDLPGGQHVTQPPSYKVL 1092
            |...|.||:||.||.||||:||:||.:.:      ..:.|.:..|.:          .||  :..
Zfish   785 SIYNGSLEIMLHRRLLYDDFRGVGEPLSEPGEFAHGLVARGRLLLTL----------SPP--EAA 837

  Fly  1093 SQQAQQLANALRYPPNLYFV-------SNLEQPELAAALLPLVRLLPKGPLPCDVHLTTL----- 1145
            :...:.||.::...|.|.|.       :.||...|.|||.|.|.||.......|..|..|
Zfish   838 ADLHRPLAQSMVLQPLLSFQDGAPSPGTKLEFSGLQAALPPAVHLLTVSQWDQDSVLVRLEHQYQ 902

  Fly  1146 ----RTLSDP---ELQ-LFPSASALLVLHRQGFDCSVSAGRELSMEAICPLSSKGLGNVQLGRLS 1202
                :|.|.|   .|| ||   |.|.||          ...|:|:         |....:...:.
Zfish   903 AKESKTHSQPVTVNLQKLF---STLQVL----------GASEMSL---------GANQWKEDMIR 945

  Fly  1203 LHTIEATSLTGTEQKSSRESYHIRSLAEISLEPMELRTFNLTFR 1246
            ||       ..||:.:...:....|..|::|:|||:|||.|..|
Zfish   946 LH-------WNTEKDALPPTARDPSSWEVTLKPMEIRTFLLRVR 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIb	NP_001262614.1	PLN02701	148..1246	CDD:178304	286/1147 (25%)
		GH38N_AMII_GMII_SfManIII_like	167..514	CDD:212120	93/356 (26%)
		Alpha-mann_mid	508..596	CDD:286360	28/87 (32%)
		Glyco_hydro_38C	813..1241	CDD:285047	121/478 (25%)
man2b1	XP_005169420.1	PLN02701	44..982	CDD:178304	286/1147 (25%)
		GH38N_AMII_LAM_like	44..322	CDD:212121	79/297 (27%)
		Alpha-mann_mid	368..446	CDD:214875	28/86 (33%)
		Glyco_hydro_38C	558..977	CDD:285047	133/537 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810