Protein Alignment alpha-Man-IIb and LManI

DIOPT Version :9

• Sequence 1: NP_001262614.1
• Gene: alpha-Man-IIb / 41913
• FlyBaseID: FBgn0026616
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: NP_001260350.1
• Gene: LManI / 34436
• FlyBaseID: FBgn0032253
• Length: 950
• Species: Drosophila melanogaster
• Alignment Length: 1169
• Identity: 286/1169 - (24%)
• Similarity: 471/1169 - (40%)
• Gaps: 324/1169 - (27%)

  Fly   168 LKIIVVPHSHNDPGWLKTFTNYFQSDSRQ--------ILNLLVTKMQEYTDMTFIWSEISFLQLW 224
            :.:.:|||||:|.|||||...|:.....:        ||:.:|.::.:.:...||..|..|...|
  Fly     2 INVHLVPHSHDDVGWLKTVDQYYYGSQNKIQHAGVQYILDTVVEELLKDSSRRFIQVETFFFAKW 66

  Fly   225 WDQAHPTKQRALKRLIDAGRIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLKNNLN--VTPKVG 287
            :.:...|.|||:|:|:..||:|...|.|.|.|||.||...::||...|.::||:...  ..|.||
  Fly    67 YSEQTETVQRAVKKLVAQGRLEFAGGAWSMNDEATVHYQSVVDQFNLGLRYLKDTFGDCGRPTVG 131

  Fly   288 WSIDPFGHGSTVPYLLSGANFEGTIIQRIHYAWKQWFARQQSGDFIWKPYWRSR---KDKDSEAG 349
            |.||||||...:..:.:...|.|....|:.|..|    :|:..|...:..|:|.   |:.:...|
  Fly   132 WQIDPFGHSREMASIFAQMAFNGEFFARMDYVDK----KQRMLDLEMEMIWQSSESLKNSNIFTG 192

  Fly   350 SLLTHNMPFDIYSIKGSCGPHPFICLNFDFRKIP---GEYTEYSVKAQFITDDNLESKAQLLLEQ 411
            .|..|      ||..      |..|.:.:....|   ||  .|        |:|::::....::.
  Fly   193 MLYNH------YSAP------PGFCFDINCEDAPIIDGE--SY--------DNNVDARVSEFIDY 235

  Fly   412 YARTASLFPHNVALIPVGDDFRYNKDREVDQQYQNYKKLIDHIMANRRL---YNADIRFGTPSDY 473
            ....:..:.....::|:||||:| :|..|:  ::|..|||.::  |.|.   ...::.:.|||.|
  Fly   236 VKNMSKSYRSTHIMVPMGDDFQY-EDAAVN--FKNMDKLIKYV--NDRQSTGSQVNVFYSTPSCY 295

  Fly   474 FEAIKERMKDHTPGFPTFKGDFFVYSDIFSEGRPAYWSGYFTTRPFYKLLSSELEHQLRSAEIVF 538
            ...:.:..:.    :|....|||.||   |:.. :||:||||:||..|....:..|..::.:.:.
  Fly   296 LYELHQLKQT----WPNKTEDFFPYS---SDSH-SYWTGYFTSRPTQKRFHRDGNHFFQTVKQLS 352

  Fly   539 TLAYNTARQAKRENAIKIYEKNYELIINARRNLGLFQHHDAITGTSKAAVMRDYAMRLFE----- 598
            .||..:..|         |.::.:   |..:.:|:.|||||:|||.|.||..||...||:
  Fly   353 VLANLSGTQ---------YSEDLD---NLSQAMGIMQHHDAVTGTEKQAVASDYDRLLFKAIVGA 405

  Fly   599 ---------STQNMVKMQ-ESCLELLLQKGQPRHHGFLLSEFERDNFNKLPRKMPIQMANGDEST 653
                     |..|:...: ||||||.:.          :..|.:|..|.:
  Fly   406 ENSARDALRSLTNLTSGEFESCLELNIS----------VCAFTQDTANNV--------------- 445

  Fly   654 PTVPAGEGGAGGSSSSGSVGSFVLYNSLAQKRLEVVTLRVQHPNVKIVNDKGVELNHIQINPV-W 717
                                ...|.|.||....:.|.:..::.|..:.::||.|: ..::.|| |
  Fly   446 --------------------IVTLVNPLAHSSTQYVRVPAKNENYIVTDEKGREV-FSEVVPVPW 489

  Fly   718 NITDTYEQGLGTSVSGTVGRIRTSTRQFEVMFVAELEPLSLSTYRVQVDEVNFKRNIATIYCDDC 782
            .:.....              |.:..|.|::|.|.::.::....||    :...:|||
  Fly   490 QVLALEH--------------RPNDTQHELVFEASVDKIANFLIRV----LPSPKNIA------- 529

  Fly   783 TESQPASVSPPEEIESSPTSVFEARGKPAGDIQLENPHMRLLFDEKSGFLKTITRKNQKKELLKP 847
             |.|   |..|.|             :...::.:|...::|.||..:|.|||: :.|...|
  Fly   530 -EDQ---VQFPVE-------------RSQDELTVETSLVKLTFDTTTGGLKTV-KMNGFTE---- 572

  Fly   848 LQCNIK-----FAAYR-----SAQFHSGAYLFKTDPEQSEAEKEVLEGYTDMRII-------ITS 895
               ||:     :..||     |....||||:|:.              |.|:.|:       ..:
  Fly   573 ---NIQQTFGIYKGYRGNNGESKNRSSGAYVFRP--------------YGDIEIVNNKVELSFYN 620

  Fly   896 GPIASDVTVIYGPFLAHTVRIFNTRTHLDAAIYVENDIDFE----PPPKNRET--ELFMRFVTNI 954
            |....:|......:::..:||:..          .|.::||    |.|.:.:.  |:..||.:||
  Fly   621 GTKVKEVHQHVNEWISQVIRIYED----------VNRVEFEWLVGPIPTDDDVGKEIITRFSSNI 675

  Fly   955 DNIAQAPMQRDPLKEPVDAATMPELPVFYSDQNGFQYHERIK------VPAI--GIEGNYFPITS 1011
            .:..:                      ||:|.||.:..||.:      .|.:  .|.|||:|:|.
  Fly   676 SSKGK----------------------FYTDSNGREILERERNQREHFTPDMSEAISGNYYPVTG 718

  Fly  1012 GAFIQDSRLRLTLLTTHAQGAASYEPGQLEVMLDRRTLYDDYRGMGEGVVDSR-----LTRHKFW 1071
            ...:||...|:|||...|||..|.:.|:||:||.||.|.||..|:||.:.:::     :.|.|.:
  Fly   719 QISLQDDEKRITLLNDRAQGGTSLKDGELELMLHRRLLNDDAFGVGEALNETQYGTGLIARGKIY 783

  Fly  1072 LLVEDLPGGQHVTQPPSYKVLSQQAQQLANALRYPPNLYFVSNLEQPELAAALLPLVRLLPK--G 1134
            |:::.:.|      .|:.::|..|..|           :|.....:....|::..  .::|.  |
  Fly   784 LILDAVDG------KPNQRLLQHQLDQ-----------HFWKFFSKSNGVASVNR--NMIPDFFG 829

  Fly  1135 PLPCDVHLTTLRTLSDPELQLFPSASALLVLHRQGFDCSVSAGRELSMEAICPLSSKGLGNVQL- 1198
             :|..|.|          |.|.|.:...:::..:.|:   :.|..:|.. |.|| .:.|...|:
  Fly   830 -IPESVEL----------LSLEPYSKDQILIRLENFN---TEGNVVSFN-IYPL-FESLDGYQIW 878

  Fly  1199 -----GRLSLHTIE----ATSLTGTEQKSSRESYHI------------RSLAEISLEPMELRTF 1241
                 |.:.|..::    |...||: ..||.|.||.            .|...::|.||::|||
  Fly   879 ETTLDGNMLLEDVKRFKFAQDGTGS-IPSSVEYYHAPHNPLTANSTMNASGFVVTLVPMQIRTF 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIb	NP_001262614.1	PLN02701	148..1246	CDD:178304	286/1169 (24%)
		GH38N_AMII_GMII_SfManIII_like	167..514	CDD:212120	103/364 (28%)
		Alpha-mann_mid	508..596	CDD:286360	29/87 (33%)
		Glyco_hydro_38C	813..1241	CDD:285047	115/487 (24%)
LManI	NP_001260350.1	GH38N_AMII_LAM_like	2..276	CDD:212121	87/304 (29%)
		Alpha-mann_mid	323..398	CDD:286360	29/86 (34%)
		Glyco_hydro_38C	536..941	CDD:285047	117/507 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450136
Domainoid	1	1.000	50	1.000	Domainoid score	I680
eggNOG	1	0.900	-	-		E1_KOG1959
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	49	1.000	Inparanoid score	I462
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.790