Protein Alignment alpha-Man-IIb and LManVI

DIOPT Version :9

• Sequence 1: NP_001262614.1
• Gene: alpha-Man-IIb / 41913
• FlyBaseID: FBgn0026616
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: NP_609253.1
• Gene: LManVI / 34206
• FlyBaseID: FBgn0032069
• Length: 1007
• Species: Drosophila melanogaster
• Alignment Length: 1146
• Identity: 277/1146 - (24%)
• Similarity: 468/1146 - (40%)
• Gaps: 230/1146 - (20%)

  Fly   156 FDAQKKDKQRPPLKIIVVPHSHNDPGWLKTFTNYF--------QSDSRQILNLLVTKMQEYTDMT 212
            ::|..|.|.. .:.|.:|||||:|.|||||...||        .:..:.|::.::.::.:.....
  Fly    27 YEACPKTKTN-MINIHMVPHSHDDVGWLKTVDQYFYGHRSNIQHAGVQYIIDTVIAELIKDPARR 90

  Fly   213 FIWSEISFLQLWWDQAHPTKQRALKRLIDAGRIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLK 277
            ||..|.||...||.:...|.::.:::|::.||:|.|.|.|.|.|||.|:...::||...|.::|.
  Fly    91 FIQVETSFFAKWWAEQSETAKQVVRKLVNEGRLEFTGGAWSMNDEAAVNYQSVIDQFTLGLKFLD 155

  Fly   278 NNLN--VTPKVGWSIDPFGHGSTVPYLLSGANFEGTIIQRIHYAWKQWFARQQSGDFIWKPYWRS 340
            :...  ..|::||.||||||......:.:...::|....|:.:..|.........:.||... .|
  Fly   156 DTFGSCARPRIGWQIDPFGHSREQASIFAQMGYDGEFFARMDHRDKNDRIDNLGMEMIWDAS-DS 219

  Fly   341 RKDKDSEAGSLLTH-NMP----FDIYSIKGSCGPHPFICLNFDFRKIPGEYTEYSVKAQFITDDN 400
            ..:.:...|.|..| :.|    ||::     ||..|.|           :...|        |:|
  Fly   220 LSNDEIFTGLLYRHYSAPPGYCFDVH-----CGDDPII-----------DTKSY--------DNN 260

  Fly   401 LESKAQLLLEQYARTASLFPHNVALIPVGDDFRYNKDREVDQQYQNYKKLIDHI---MANRRLYN 462
            ::|:....|......|..:..|..:||:||||:| :|.:|:  ::|..|||.::   .|....:|
  Fly   261 VKSRVDDFLSYVTSVAQHYRSNHIMIPMGDDFQY-EDAQVN--FKNMDKLIKYVNERQAEGSTFN 322

  Fly   463 ADIRFGTPSDYFEAIKERMKDHTPGFPTFKGDFFVY-SDIFSEGRPAYWSGYFTTRPFYKLLSSE 526
              :.:.||:.|..::.|.::.    :|....|||.| ||..|     ||:||||:||..|....:
  Fly   323 --LFYSTPACYLNSLHEGLQT----WPNKTQDFFPYGSDDNS-----YWTGYFTSRPTQKRFERD 376

  Fly   527 LEHQLRSAEIVFTLAYNTARQAKRENAIKIYEKNYELIINARRNLGLFQHHDAITGTSKAAVMRD 591
            ..|.|:.|:.:...|....:|.|.:            :...|..:|:.|||||||||.|..|..|
  Fly   377 GNHILQVAKQLSVFAELNTKQQKED------------LEYLREIMGVMQHHDAITGTEKQHVSDD 429

  Fly   592 YAMRLFESTQNMVKMQESCLELLLQKGQPRHHGFLLSEFERDNFNKLPRKMPIQMANGD-ESTPT 655
            |...|:::....|..                        .||...||     ..:.||: ||...
  Fly   430 YDRILYDAILGGVNT------------------------ARDGLRKL-----TNLPNGEFESCLQ 465

  Fly   656 VPAGEGGAGGSSSSGSVGSFVLYNSLAQKRLEVVTLRVQHPNVKIVNDKGVELNHIQINPVWNIT 720
            :...|.......:...|  ..|||.||....:.|.:.|::.|.::.::||..:....:...|.:.
  Fly   466 LNISECAFTKDDADNVV--VTLYNPLAHTSTQYVRVPVKNENYEVTDEKGRVVASEVVPVAWQVL 528

  Fly   721 DTYEQGLGTSVSGTVGRIRTSTRQFEVMFVAELEPLSLSTYRVQVDEVNFKRNIATIYCDDCTES 785
            ..              ..|.:..|.|::|.|.::.:: :.|..:|.....|...|........::
  Fly   529 AL--------------EFRNNDTQHELVFKASVDKIA-NYYIKKVASQETKNVAAHTKSKRSIKA 578

  Fly   786 QPASVSPPEEIE-----SSPTSVFEARGKPAGDIQLENPHMRLLFDEKSGFLKTITRKNQKKELL 845
            :.|::..|:..:     .:.|..|:   ...|:..::...::|:.|.|:|.|||:......:.:
  Fly   579 EEANLEVPKRFKKVHSLKNATETFD---DDEGETVVQTSQVKLVIDNKTGLLKTVEMNGVSENI- 639

  Fly   846 KPLQCNIKFAAYRSAQFHSGAYLFKTDPEQSEAEKEVLEGYTDMRIIITSGPIASDVTVIYGPFL 910
                 :..:..||:  :.||||:|:     ...:.:.:..|..:...:..|.:..:|...:..::
  Fly   640 -----DQSYGVYRT--YDSGAYVFR-----QYHQADFIVQYEGVEFTVYDGALVKEVHQQFSEYI 692

  Fly   911 AHTVRIFNTRTHLDAAIYVENDIDFEPPPKNRETELFMRFVTNIDNIAQAPMQRDPLKEPVDAAT 975
            :..:||:..:..:        :|:::..|..||.| |.|.|..|.|                 :|
  Fly   693 SQVIRIYEGKNLV--------EIEWQVGPIEREEE-FGREVVIIFN-----------------ST 731

  Fly   976 MPELPVFYSDQNGFQYHERIK------VPAIGIE---GNYFPITSGAFIQDSRLRLTLLTTHAQG 1031
            :....|.|:|.||.:..:|:|      .|.:..:   .||:|:||...:|||:.|:.:|...|||
  Fly   732 IASDGVSYTDSNGREMIKRVKDQRETFTPGLDRQPTAANYYPVTSRIALQDSKKRIAVLNDRAQG 796

  Fly  1032 AASYEPGQLEVMLDRRTLYDDYRGMGEGVVDSRLTRHKFWLLVEDLPGGQHVTQPPSYKVLSQQA 1096
            .||...||||:||.||.:.||..|:||.             |.|:..|...:.:...|.:||...
  Fly   797 GASMLNGQLELMLHRRLVRDDGYGVGEA-------------LNEEKYGQPMIARGKVYLILSPSD 848

  Fly  1097 QQLA------NALRYPPNLYFVSNLEQPELAAALLPLVRLLPKGPLPCDVHLTTLRTLSDPELQL 1155
            :..|      ..:..|...:|..|......||..:|.....||     .|||.||...:|.|:.|
  Fly   849 ESTAAEREAEKEIHLPFWKFFSKNTGSTTAAAKSVPSFNDFPK-----SVHLLTLEPFNDDEVLL 908

  Fly  1156 FPSASALLVLHRQGFDCSVSAG-----------RELSMEAICPLSSKGLGNVQLGRLSLH----- 1204
               .....:.|.:|...|.:..           ||.:::...|||       .:.|...|
  Fly   909 ---RVENFLDHTEGQVVSFNIRPIFDYLNGVEIRETTLDGNLPLS-------DMKRFKFHHDSSG 963

  Fly  1205 ----TIEATSLTGTEQKSSRESYHIRSLAEISLEPMELRTF 1241
                .:|  ..|...:..:.|.....|...::|.||::|||
  Fly   964 QKPDAVE--YFTSAHKPLAAEQSQEASEFSVTLHPMQIRTF 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIb	NP_001262614.1	PLN02701	148..1246	CDD:178304	277/1146 (24%)
		GH38N_AMII_GMII_SfManIII_like	167..514	CDD:212120	101/365 (28%)
		Alpha-mann_mid	508..596	CDD:286360	30/87 (34%)
		Glyco_hydro_38C	813..1241	CDD:285047	107/462 (23%)
LManVI	NP_609253.1	GH38N_AMII_LAM_like	38..312	CDD:212121	84/301 (28%)
		Alpha-mann_mid	359..434	CDD:286360	30/86 (35%)
		Glyco_hydro_38C	482..1002	CDD:285047	133/608 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450134
Domainoid	1	1.000	50	1.000	Domainoid score	I680
eggNOG	1	0.900	-	-		E1_KOG1959
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	49	1.000	Inparanoid score	I462
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.790