Protein Alignment alpha-Man-IIb and aman-3

DIOPT Version :9

• Sequence 1: NP_001262614.1
• Gene: alpha-Man-IIb / 41913
• FlyBaseID: FBgn0026616
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: NP_001361919.1
• Gene: aman-3 / 172178
• WormBaseID: WBGene00018594
• Length: 1046
• Species: Caenorhabditis elegans
• Alignment Length: 1167
• Identity: 315/1167 - (26%)
• Similarity: 514/1167 - (44%)
• Gaps: 229/1167 - (19%)

  Fly   120 IQSNTNITASEEHSKFDFQPEWMRSKEYWDRGFEE------RFD--------------AQKKDKQ 164
            ::...|::.|:::... |:|:    .|...|...|      .||              |.||.:.
 Worm    57 VKEANNLSNSQKNPNI-FEPK----NEVCQRPLTESSTNFNTFDLFESVVAKGNTLPPASKKSRT 116

  Fly   165 RPPLKIIVVPHSHNDPGWLKTFTNYFQSDSRQILNLLVTKMQEYTDMTFIWSEISFLQLWWDQAH 229
            . .||:.|:|.:|.|||||:||..|.:| :.|||:.:...|.:...|.|:|:|..|.:.||...:
 Worm   117 E-KLKVYVLPFTHVDPGWLETFERYTKS-TNQILDNMHQFMMKNEKMRFMWAEFVFFERWWSLQN 179

  Fly   230 PTKQRALKRLIDAGRIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLKNNLNVTPKVGWSIDPFG 294
            ...:..:|:|:..||:|:.||.||||||||.:....:|.::||.|::..|..:.|:..||.||||
 Worm   180 EQVKEDVKKLVTEGRLELATGSWVMTDEANPYFPVSVDNIVEGFQFIHKNFGIKPQTMWSNDPFG 244

  Fly   295 HGSTVPYLLSGANFEGTIIQRIHYAWKQWFARQQSGDFIWKPYWRSRKDKDSEAGSLLTHNMPFD 359
            :.::||||...:....|:|.|||:..||....|::..|.|:.|:.:..:.|     :||..:|:.
 Worm   245 YSNSVPYLFKKSGVHRTVINRIHHKLKQTLQSQKAIPFKWRQYFDATGEDD-----VLTQILPYT 304

  Fly   360 IYSIKGSCGPHPFICLNFDFRKIPGEYTEYSV---KAQFITDDNLESKAQLLLEQYARTASLFPH 421
            .|.|..|||....:|..|||:::    |.:|.   |.:.||:.|:.:||:.|:.|..:.:.::..
 Worm   305 HYDILNSCGSDASVCCEFDFKRM----THWSCPGPKPEKITNANVAAKAEKLVNQLEKMSEMYKA 365

  Fly   422 NVALIPVGDDFRYNKDREVDQQYQNYKKLIDHIMANRRLYNADIRFGTPSDYFEAIKE---RMKD 483
            .|.|:..|||||::...|.:||:.|:..:.|.|....|:   :|||||.:|||..:::   ..||
 Worm   366 PVILMMHGDDFRFDMIEEWNQQHDNFIPVFDEINKGSRV---EIRFGTFTDYFNDLEKWYSNNKD 427

  Fly   484 HTPGFPTFKGDFFVYSDIFSEGRPAYWSGYFTTRPFYKLLSSELEHQLRSAEIVFTLAYNTARQA 548
            ..|  ||..||||.|.....:    ||:||:|||||:|.....|...:|:.:|:.::.....:|.
 Worm   428 SEP--PTVSGDFFPYMCALGD----YWTGYYTTRPFFKRQGRLLHSLIRNGDIMLSMLRVNLKQR 486

  Fly   549 KRENAIKIYEKNYELIINARRNLGLFQHHDAITGTSKAAVMRDYAMRLFESTQNMVKMQESCLEL 613
            |....:|..|.       |||||.|||||||||||||.:||.:|:                  ||
 Worm   487 KIGENVKRLEA-------ARRNLALFQHHDAITGTSKVSVMDNYS------------------EL 526

  Fly   614 LLQKGQPRHHGFLLSEFERDNFNKLPRKMPIQMANGDESTPTVPAGEGGAGGSSSSGSVGSFVLY 678
            |       |...:.:....:|..|....:..::.:|.|....|..       .||...:.   ::
 Worm   527 L-------HASIVSTNIVLENLTKSDIDLYPRIHDGIELQTIVDL-------ESSEKEIR---IF 574

  Fly   679 NSLAQKRLEVVTLRVQHPNVKIVNDKGVELNHIQINPVWNITDTYEQGLGTSVSGTVGRIRTSTR 743
            ||...:..:|..:||:...| ||:..| ::...|:.|.:.                  :.:....
 Worm   575 NSHLFEITDVFKIRVKEREV-IVSIDG-KIIEAQLEPFFQ------------------KSKVEKD 619

  Fly   744 QFEVMFVAELEPLSLSTYRVQVDEVNFKRNIATIYCDDCTESQPASVSPPEEIESSPTSVFEARG 808
            .|.::|.|.:.|||:...:||..:......:|.|...|.......|........|:|
 Worm   620 SFLLLFQATVLPLSMMKVKVQRGDSGGLTKMAKIEAKDTNAWDLGSSWTIASSTSAP-------- 676

  Fly   809 KPAGDIQLENPHMRLLFDEKSGFLKTITRKNQKKELLKPLQCNIKFAAYRSAQFHSGAYLFK--T 871
                  .||.|:.::..|..:|.::::.:.:...:    ..|...|..|:.|  ..||||.:  |
 Worm   677 ------NLETPYFKVSNDPITGAIQSVNKLSDNSK----FHCQQSFYNYKEA--GGGAYLMRLHT 729

  Fly   872 DPEQSEAEKEVLEGYTDMRIIITSGPIASDVTVIY--GPFLAHTVRIFNTRTHLDAAIYVENDID 934
            :|      ||::| |..:::   |||:...   ||  ...:...:.|.|........:.:...||
 Worm   730 NP------KEIIE-YQWLKV---SGPLRQS---IYQKSTNVLQRLSIHNVEGPSGEEVDISMSID 781

  Fly   935 FEPPPKNRETELFMRFVTNIDNIAQAPMQRDPLKEPVDAATMPELPVFYSDQNGFQYHER--IKV 997
            .   .|.|.|||..||.|..|.                       |:.|:|..|.|...|  .|:
 Worm   782 I---TKERNTELMTRFSTKWDK-----------------------PLTYTDSVGMQLLRRDFYKL 820

  Fly   998 PAIGIEGNYFPITSGAFIQDSRLRLTLLTTHAQGAASYEPGQLEVMLDRRTLYDDYRGMGEG--- 1059
            |   ::.||:|:.:.|.:|..:.||::::....||...|.|.:|:.:||....||.:|:|.|
 Worm   821 P---VQSNYYPMPTAAVLQSGKQRLSIVSNVEHGARFLESGTVEINIDRILNQDDGKGLGTGPDA 882

  Fly  1060 -VVDSRLTRHKFWLLVEDLPGGQHVTQPPSYKVLSQQAQQLANALRYPPNLYFVSNLEQPELAAA 1123
             .:|.:....||.|:.:.|....  |:...|...|.:|||....:.|||.::     .:|.....
 Worm   883 IPIDMKPVDMKFKLIFDSLESDP--TENSRYSTHSFRAQQAVQTIIYPPMMF-----NRPPKKEE 940

  Fly  1124 LLPLVRLLPKGPLPCDVHLTTLRTLSDPELQLFPSASALLVLHRQGFDCSV----SAGRELS--- 1181
            .:..:..:.....|||:.|.|:|.|.|.:        .||:|:|....||.    :.|.||.
 Worm   941 DIEEIEEISNLKFPCDIQLLTVRPLEDNK--------QLLILYRHATVCSSQKVGNCGGELKSSL 997

  Fly  1182 MEAICPLSSKGLGNVQLGRLSLHTIEATSLTGTEQKSSRESYHIRSLAEISLEP-MELRTFN 1242
            |:.:..|.:|             .::.|.|:|..:        :..:.::...| .||:||:
 Worm   998 MDLLIKLGAK-------------QVQKTDLSGVTR--------VGGIIKVEYLPDYELKTFD 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIb	NP_001262614.1	PLN02701	148..1246	CDD:178304	310/1139 (27%)
		GH38N_AMII_GMII_SfManIII_like	167..514	CDD:212120	125/352 (36%)
		Alpha-mann_mid	508..596	CDD:286360	38/87 (44%)
		Glyco_hydro_38C	813..1241	CDD:285047	105/445 (24%)
aman-3	NP_001361919.1	PLN02701	117..978	CDD:178304	287/1019 (28%)
		GH38N_AMII_GMII_SfManIII_like	118..452	CDD:212120	125/352 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1101882at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.880