Protein Alignment alpha-Man-IIb and alpha-Man-IIa

DIOPT Version :10

• Sequence 1: NP_650494.2
• Gene: alpha-Man-IIb / 41913
• FlyBaseID: FBgn0026616
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: XP_318477.5
• Gene: alpha-Man-IIa / 1278838
• VectorBaseID: AGAMI1_006571
• Length: 1139
• Species: Anopheles gambiae
• Alignment Length: 1243
• Identity: 379/1243 - (30%)
• Similarity: 576/1243 - (46%)
• Gaps: 244/1243 - (19%)

  Fly    62 SVDGG-----SSSII--------HQQKQQLVIASNQKKSSETKSAQTSVSPEEQSEEQYTNSNWG 113
            :||||     .|.|:        .:..::.||.:| ...:.|.:.:|.:.|  |.:.|..|
Mosquito    74 AVDGGDDAYADSKILDKAPLLGDREMMKESVINAN-GGGAGTCALRTDIIP--QPDVQMLN---- 131

  Fly   114 DKCYELIQSNTNITASEEHSKFDFQPEWMRSKEYWDRGFEERFDAQKKDKQRPPLKIIVVPHSHN 178
              .||.: |..||...                 .|.:|:..::...:.:... .|.:.|||||||
Mosquito   132 --LYEQV-SFENIDGG-----------------VWKQGWPIKYHPSEWNSHH-KLHVFVVPHSHN 175

  Fly   179 DPGWLKTFTNYFQSDSRQILNLLVTKMQEYTDMTFIWSEISFLQLWWDQAHPTKQRALKRLIDAG 243
            ||||::||..|::..::.|...::..:.|...|.|||:|||:...|:|:....::..:|||:...
Mosquito   176 DPGWIQTFDEYYERSTKNIFANMLRHLDENAGMRFIWAEISYFAQWYDKLAAEQKDIVKRLVKKR 240

  Fly   244 RIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLKNNLNVTPKVGWSIDPFGHGSTVPYLLSGANF 308
            ::|..||||||.||||.|.|.||.||.||..||:..|||||...|||||||..:|:||:|..:.|
Mosquito   241 QLEFVTGGWVMPDEANSHWYSMLLQLTEGQTWLQTRLNVTPVSSWSIDPFGQSATMPYILKQSGF 305

  Fly   309 EGTIIQRIHYAWKQWFARQQSGDFIWKPYWRSRKDKDSEAGSLLTHNMPFDIYSIKGSCGPHPFI 373
            |..:|||.||..|:..|.::..:|.|:..|.:|.|.|     |.||.|||..|.:..:|||.|.|
Mosquito   306 ENLLIQRTHYIVKKNLALKKQLEFRWRQLWDTRGDTD-----LFTHMMPFYSYDVPHTCGPDPKI 365

  Fly   374 CLNFDFRKIP--GEYTEYSVKAQFITDDNLESKAQLLLEQYARTASLFPHNVALIPVGDDFRYNK 436
            |..|||:::|  |....::|..:.|||.|:..:|:::::|:.:.:.|:.....|||:||||||..
Mosquito   366 CCQFDFKRLPSMGLSCPWNVPPKPITDQNVAERAEMIVDQWRKKSVLYRTRNVLIPLGDDFRYTT 430

  Fly   437 DREVDQQYQNYKKLIDHIMANRRLYNADIRFGTPSDYFEAIKERMKDHTPG------FPTFKGDF 495
            ..|.:.|..|:::|.::| .|....|.:.:|.|..|||:|::.     |.|      ||:..|||
Mosquito   431 SSEWEAQRVNFEQLFNYI-NNEPSLNVEAKFATLQDYFDAVRS-----TSGASGMEQFPSLTGDF 489

  Fly   496 FVYSDIFSEGRPAYWSGYFTTRPFYKLLSSELEHQLRSAEIVFTLAYNTARQAKRENAIKIYEKN 560
            |.|:|:..:    |||||||:||::|.....|.|.:||||::              :|..::|.:
Mosquito   490 FTYADVNQD----YWSGYFTSRPYHKRQDRILLHYIRSAEML--------------HAWNVWEPD 536

  Fly   561 ------YELIINARRNLGLFQHHDAITGTSKAAVMRDYAMRLFESTQN-MVKMQESCLELLLQKG 618
                  .|.:..|||.|.||||||.||||:|..||.|||.|:..:.:: ...||:|...||.:..
Mosquito   537 SDWKPLAERLEYARRQLSLFQHHDGITGTAKDHVMEDYAKRMSRAIEDCKFVMQQSVYRLLTKPS 601

  Fly   619 --QPRHHGFLLSEFERDNFNKLPRKMPIQMANGDESTPTVPAGEGGAGGSSSSGSVGSFVLYNSL 681
              ||......||..:....|           ..|...||:..||     ...|..|   ||:|||
Mosquito   602 VYQPDPAFMYLSIDDSRTVN-----------GSDNVRPTIILGE-----ELPSKQV---VLHNSL 647

  Fly   682 AQKRLEVVTLRVQHPNVKIVNDKGVELNHIQINPVWNITDTYEQGLGTSVSGTVGRIRTSTRQFE 746
            ...|.|||...|..|.|.:::..|..:.. ||.|||:         ..:...::.:.:.|..::.
Mosquito   648 PYTRSEVVEFYVASPFVTVLDGNGGTVPS-QIAPVWS---------WHTRPDSISQPQPSNTKYR 702

  Fly   747 VMFVAELEPLSLSTYRVQVDEVNFKRNIATIYCDDCTESQPASVSPPEEIESSPTSVFEARGKPA 811
            ::|.|.:.||.||.|     .:|.|        :...||...:.:....:..||.:|..|.|.|.
Mosquito   703 LLFRANVPPLGLSVY-----TINSK--------NSAEESLGVTYTKVIILSKSPFTVNLAAGYPE 754

  Fly   812 GDIQLENP-HMRLLFDE---------KSGFLKTITRKNQKKELLKPLQCNIKFAAY--RSAQFHS 864
             ||...:| .|.|.|:|         ..|.||::|.:|.:..:  |:  :::|..|  :.:...|
Mosquito   755 -DIDHASPTEMSLRFEEGGSTSAAFTSKGLLKSLTIENNQATV--PV--HLEFYRYGMQLSSGKS 814

  Fly   865 GAYLFKTDPEQSEAEKEVLEGYTDMRIIITSGPIASDVTVIYG-PFLAHTVRIFNTRTHL-DAAI 927
            |||||      ..|....|..|....:::..||:.:.:|.  | ||..|       :|.| |.::
Mosquito   815 GAYLF------HPAGNATLMTYDQPIVLVMKGPLETSITA--GLPFAVH-------QTILRDDSV 864

  Fly   928 YVENDIDFEPPPKNRETELFMRFVTNIDNIAQAPMQRDPLKEPVDAATMPELPVFYSDQNGFQYH 992
            .:.|.:|.   .:...||:.||..|||::.|                      .||:|.||.|..
Mosquito   865 EIRNLVDI---GQRDNTEIVMRLQTNINSGA----------------------TFYTDLNGMQII 904

  Fly   993 ERIKVPAIGIEGNYFPITSGAFIQDSRLRLTLLTTHAQGAASYEPGQLEVMLDRRTLYDDYRGMG 1057
            :|.:...:.|:.||:|:.|..||:|...|||||.....|.:|...|::|:|.|||...||.||:|
Mosquito   905 KRKRFQKLPIQANYYPVPSTMFIEDDNYRLTLLGGQPLGGSSLSSGEMEIMQDRRLTRDDDRGLG 969

  Fly  1058 EGVVDSRLTRHKFWLLVEDLPGGQHVTQP-PSYKVLSQQAQQLANALRYPPNLYFVSNLEQPELA 1121
            :||.|:....|.|.|::|   ..:..|:| |.                ||..  |::.....:|.
Mosquito   970 QGVQDNLPVLHLFRLVLE---SRESCTKPDPD----------------YPTG--FLTLPAHAQLQ 1013

  Fly  1122 AALLPLVRLL----------------PKGPLPCDVHLTTLRTLSDPELQLFPSASAL-LVLHRQG 1169
            :.|.||.:|:                ...||...:.:..:|.||.........||.: |::||..
Mosquito  1014 SLLHPLDKLIYNENDWTGVQMESFGSRHEPLEQGLEVVAIRQLSHVHFGRTSGASPVGLIVHRTN 1078

  Fly  1170 F-DCSVSAGRELSMEAICPLSSKGLGNVQLGRLSLHTIEATSLTGTEQKSSRESYHIRSLAEISL 1233
            | ||    |.|.:||.:  |:.|.|.|:.    ..|.|.:..||      ..:...:....:|||
Mosquito  1079 FEDC----GSEANMEGM--LNIKKLLNLD----DEHDIYSARLT------LLKPLELVPSDDISL 1127

  Fly  1234 EPMELRTF 1241
            .||:.:.:
Mosquito  1128 CPMDAKAY 1135

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIb	NP_650494.2	PLN02701	148..1246	CDD:178304	359/1144 (31%)
alpha-Man-IIa	XP_318477.5	None