Protein Alignment alpha-Man-IIb and man2a1

DIOPT Version :9

• Sequence 1: NP_001262614.1
• Gene: alpha-Man-IIb / 41913
• FlyBaseID: FBgn0026616
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: NP_001163963.1
• Gene: man2a1 / 100036612
• XenbaseID: XB-GENE-961025
• Length: 1150
• Species: Xenopus tropicalis
• Alignment Length: 1310
• Identity: 422/1310 - (32%)
• Similarity: 633/1310 - (48%)
• Gaps: 228/1310 - (17%)

  Fly     4 KLFRR----GSARCIGLLSAFVTILLCLYYI----SIGQPNPTPISETGAPSAAL---------- 50
            ||.|:    |||       .|..::..||.:    ...||. :|..|...|...|
 Frog     2 KLSRQITVLGSA-------IFCVVIFSLYLMLDRGQFDQPK-SPRREGALPKGQLSILQDKIDHL 58

  Fly    51 ------RGSPLSGLTGFSVDGGSSSIIHQQKQQLVIASNQKKSSETKSAQTSVSPEEQSEEQYTN 109
                  ....:|.:.. ||...|.|:...||.......::..||:.:.:..:..|....:.|:.:
 Frog    59 ERLLAENNEIISNIRD-SVINLSESVKDGQKNSDSQNFSRGSSSQLEPSAPAFLPINNEDCQFAS 122

  Fly   110 SNWGDKCYELIQSNTNITASEEHSKFDFQPEWMRSKEYWDRGFEERFDAQKKDKQRPPLKIIVVP 174
            ...|.|      ||..:....:...|| .|:    ...|.:||:..:|..:.|.:  ||::.:||
 Frog   123 VTGGHK------SNVQMLDVYDILPFD-NPD----GGVWKQGFDISYDEHEWDNE--PLQVFLVP 174

  Fly   175 HSHNDPGWLKTFTNYFQSDSRQILNLLVTKMQEYTDMTFIWSEISFLQLWWDQAHPTKQRALKRL 239
            ||||||||||||.:||:..::.|||.:|.|:||..:..|:|||||:...|||.....|:.|:|||
 Frog   175 HSHNDPGWLKTFDDYFRDQTQHILNNMVIKLQEDKNRKFMWSEISYFSKWWDGIDNQKKEAVKRL 239

  Fly   240 IDAGRIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLKNNLNVTPKVGWSIDPFGHGSTVPYLLS 304
            |:..:.||.||||||.|||..|.:.::||||||||||:.||.|.||.||:||||||..|:.|:|.
 Frog   240 IELEQFEIVTGGWVMPDEATPHYFSLVDQLIEGHQWLEKNLGVKPKSGWAIDPFGHSPTMAYILK 304

  Fly   305 GANFEGTIIQRIHYAWKQWFARQQSGDFIWKPYWRSRKDKDSEAGSLLTHNMPFDIYSIKGSCGP 369
            .:.....:|||:||:.|::||.:|:.:|.|:..|......|     :|.|.|||..|.:..:|||
 Frog   305 SSGLSNMLIQRVHYSIKKYFASKQTLEFFWRQNWDLGHSTD-----ILCHMMPFYSYDVPHTCGP 364

  Fly   370 HPFICLNFDFRKIPGEYTE--YSVKAQFITDDNLESKAQLLLEQYARTASLFPHNVALIPVGDDF 432
            .|.||..|||:::||....  :.|..:.|.:.|::.:|.::|:||.:.:.|:...|.|:|:||||
 Frog   365 DPKICCQFDFKRLPGSRVSCPWRVPPEVINEGNVQHRAWMILDQYRKKSKLYRTKVLLVPLGDDF 429

  Fly   433 RYNKDREVDQQYQNYKKLIDHIMANRRLYNADIRFGTPSDYFEAIKERMKDHTP---GFPTFKGD 494
            ||....|.||||:||:||..::.::..|: ...:|||.||||:|:::......|   .||...||
 Frog   430 RYTDSLEWDQQYENYQKLFSYMNSHPELH-VKAQFGTISDYFKALRKAGNVDDPNSQSFPVLSGD 493

  Fly   495 FFVYSDIFSEGRPAYWSGYFTTRPFYKLLSSELEHQLRSAEIVFTLAYNTARQAKRENAIKIYEK 559
            ||.|:|....    |||||||:|||||.|...:|..||:|||:::.|.....:..:..:....|
 Frog   494 FFTYADRDDH----YWSGYFTSRPFYKRLERVMESHLRAAEILYSFALVQMNKFDKLQSFPSVE- 553

  Fly   560 NYELIINARRNLGLFQHHDAITGTSKAAVMRDYAMRLFESTQNMVKMQESCLELLLQKGQ----- 619
            :|:|:..|||||||||||||||||:|..|:.||..|||.|..|:.::......:|:.|.:
 Frog   554 HYKLLTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFHSLMNLKRVIIDAAHVLVLKDKDTYAY 618

  Fly   620 -PRHHGFLLSEFERDNFNKLPRKMPIQMANGDESTPTVPAGEGGAGGSSSSGSVGSFVLYNSLAQ 683
             |....|.:.:.:... :.||:|..|::..       :|.               ...:||...|
 Frog   619 NPSSPFFSMDDVQPSQ-DSLPQKTVIKITE-------IPR---------------YLTVYNPTEQ 660

  Fly   684 KRLEVVTLRVQHPNVKIVNDKGVELNHIQINPVWN-----ITDTYEQGLGTSVSGTVGRIRTSTR 743
            :|..||::.|....||:::..|..|. .||:.|||     :.|.|
 Frog   661 ERYSVVSVYVSSSKVKVISASGKALK-AQISAVWNGDSAPLQDMY-------------------- 704

  Fly   744 QFEVMFVAELEPLSLSTYRVQVDEVNFKRNIATIYCDDCTESQPASVSPPEEIESSPTSVFEARG 808
              :|.|:|.|..|.|:.|:: |:..|                       .|.|::..|...:.:.
 Frog   705 --QVSFLAYLPALGLAVYKL-VEAEN-----------------------SESIKADYTIFVQGKH 743

  Fly   809 K---------------PAGDIQLENPHMRLLFDEKSGFLKTITRKNQKKELLKPLQCNIKFAAYR 858
            |               ..||:.:||.:::|.| ..||.|:.|    |.||..|.....:.|..|.
 Frog   744 KNINSDGNFRIKEVNIVVGDVTIENTYLKLWF-SSSGLLEKI----QSKEDGKTHGVKVDFIWYG 803

  Fly   859 SA--QFHSGAYLFKTDPEQS---EAEKEVLEGYTDMRIIITSGPIASDVTVIYGPFLAHTVRIFN 918
            :.  :..||||||..|.|..   .|:..|:.        :|.|.|.|:| |::...|.||||::|
 Frog   804 TTNNRDKSGAYLFLPDGEAKPYINADPPVVR--------VTHGSIFSEV-VVFFKHLTHTVRLYN 859

  Fly   919 TRTHLDAAIYVENDIDFEPPPKNRETELFMRFVTNIDNIAQAPMQRDPLKEPVDAATMPELPVFY 983
            .......:..:.|.:|.. ...||  |:.||..::|::..:                      ||
 Frog   860 VHGLEGQSPEITNVVDIR-GEFNR--EIVMRITSDINSKHR----------------------FY 899

  Fly   984 SDQNGFQYHERIKVPAIGIEGNYFPITSGAFIQDSRLRLTLLTTHAQGAASYEPGQLEVMLDRRT 1048
            :|.||:|...|..:..:.|:.|.:|:||.|:|||...||||.:..:.|.||.:.|||||.||||.
 Frog   900 TDLNGYQIQPRRTLSKLPIQANVYPMTSMAYIQDDASRLTLHSAQSLGVASSKSGQLEVFLDRRL 964

  Fly  1049 LYDDYRGMGEGVVDSRLTRHKFWLLVEDLPG--GQHVTQPPSY-KVLSQQAQQLANALRYPPNLY 1110
            :.||.||:|:||.|:::|.:.|.||:|...|  .:...:|.|| .:||.......|....|  :.
 Frog   965 MQDDNRGLGQGVQDNKITSNLFRLLLEKRFGKDEKEDEKPVSYPSILSHITSMFLNHPVIP--MA 1027

  Fly  1111 FVSNLEQPELAAALLPLVRLLPKGPLPCDVHLTTLRTLSDPELQLFPSASALLVLHRQGFDCSVS 1175
            ..|:.....|..|.|||.     ..:||||||..|||: ..::...||..|.|:|||:||||..|
 Frog  1028 ATSDSGSSVLLNAFLPLT-----SSMPCDVHLLNLRTI-QAKVGPIPSDEAALILHRKGFDCKFS 1086

  Fly  1176 AGRELSMEAICPLSSKGLGNVQLGRL----SLHTIEATSLTGTEQKSSRESYHIRSLAEISLEPM 1236
             .::|.:     |.|...|.|.:.||    ::.::..:|||.....|:.     ::..||.:..|
 Frog  1087 -NKDLGL-----LCSTTQGKVSVHRLFNGFNIESLIPSSLTLMHSSSNS-----KNTTEIRISTM 1140

  Fly  1237 ELRTFNLTFR 1246
            :::||.:..|
 Frog  1141 DIKTFRIKLR 1150

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIb	NP_001262614.1	PLN02701	148..1246	CDD:178304	388/1140 (34%)
		GH38N_AMII_GMII_SfManIII_like	167..514	CDD:212120	156/351 (44%)
		Alpha-mann_mid	508..596	CDD:286360	44/87 (51%)
		Glyco_hydro_38C	813..1241	CDD:285047	139/439 (32%)
man2a1	NP_001163963.1	PLN02701	130..1150	CDD:178304	392/1165 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6357
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1101882at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010