DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9593 and TNR

DIOPT Version :9

Sequence 1:	NP_650493.2	Gene:	CG9593 / 41912	FlyBaseID:	FBgn0038365	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_003276.3	Gene:	TNR / 7143	HGNCID:	11953	Length:	1358	Species:	Homo sapiens

Alignment Length:	225	Identity:	75/225 - (33%)
Similarity:	110/225 - (48%)	Gaps:	15/225 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 PAKSDC-HELDEGVRVDGVYRFLVPERNEVQRDLYERYCAFATDGPAWTVIQSR-GGSFDPHENF 212
            |...|| ..|..|..:.|||...:  ..|:.:.| :.||...|||..|.|.|.| .|..|    |
Human  1133 PHPQDCAQHLMNGDTLSGVYPIFL--NGELSQKL-QVYCDMTTDGGGWIVFQRRQNGQTD----F 1190

  Fly   213 NRSWDEYRAGFGNLSRDFWFGNEFAHKILYRDDHELRIELQEAGEPLDWAEYPLFWLDSESYNYQ 277
            .|.|.:||.||||:..:||.|.:..|:|..:..:|||::::: |:...:|.|..|.::.....|:
Human  1191 FRKWADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRD-GQEAAFASYDRFSVEDSRNLYK 1254

  Fly   278 LSVAGEFRGSLPDALEQHNRMDFSTYDRRRNHAKSADSTCGEDYGGGWWFDRCTQCNLNGEHGVH 342
            |.: |.:.|:..|:|..|....|||.||..:   .|.:.|...|.|.||:..|.:.||||::| .
Human  1255 LRI-GSYNGTAGDSLSYHQGRPFSTEDRDND---VAVTNCAMSYKGAWWYKNCHRTNLNGKYG-E 1314

  Fly   343 QRASPAIIWMNWRTGTDKPKSSRMMIRPVN 372
            .|.|..|.|.:|:..........|.:||.|
Human  1315 SRHSQGINWYHWKGHEFSIPFVEMKMRPYN 1344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9593	NP_650493.2	FReD	150..371	CDD:238040	73/222 (33%)
TNR	NP_003276.3	EGF_2	<208..230	CDD:285248
		EGF_2	267..292	CDD:285248
		EGF_2	299..323	CDD:285248
		fn3	328..398	CDD:278470
		fn3	416..496	CDD:278470
		fn3	505..583	CDD:278470
		FN3	595..679	CDD:238020
		fn3	687..766	CDD:278470
		fn3	776..855	CDD:278470
		fn3	865..944	CDD:278470
		fn3	954..1026	CDD:278470
		FN3	1042..1127	CDD:238020
		FReD	1133..1342	CDD:238040	72/221 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810