DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9593 and Tnn

DIOPT Version :9

Sequence 1:	NP_650493.2	Gene:	CG9593 / 41912	FlyBaseID:	FBgn0038365	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_808507.2	Gene:	Tnn / 329278	MGIID:	2665790	Length:	1560	Species:	Mus musculus

Alignment Length:	261	Identity:	78/261 - (29%)
Similarity:	114/261 - (43%)	Gaps:	27/261 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 QEPSPSQTLPKELTEEKDEPK----------VDFYQPAKSDCHELDEGVR-VDGVYRFLVPERNE 177
            |:.....|.|..|...|...:          ||...|..|||.::.:... ..|:|...:  ..:
Mouse  1291 QDLEQGVTYPVSLVAFKGNQRSRTVSTTLSTVDARFPHPSDCSQVQQNTNAASGLYTIYL--NGD 1353

  Fly   178 VQRDLYERYCAFATDGPAWTVIQSRG-GSFDPHENFNRSWDEYRAGFGNLSRDFWFGNEFAHKIL 241
            ..|.: :.||...|||..|.|.|.|. |..|    |.:.|..|..|||:..::||.|.:..|.:.
Mouse  1354 ASRPM-QVYCDMDTDGGGWIVFQRRNTGQLD----FFKRWRSYVEGFGDPMKEFWLGLDKLHNLT 1413

  Fly   242 --YRDDHELRIELQEAGEPLDWAEYPLFWLDSESYNYQLSVAGEFRGSLPDALEQHNRMDFSTYD 304
              ....:|:|.:||...|.. :|.|..|.:.|....|:||| |::||:..|||..||...|:|:|
Mouse  1414 TGTTTRYEVRADLQTFNESA-YAVYDFFQVASSKERYKLSV-GKYRGTAGDALTYHNGWKFTTFD 1476

  Fly   305 RRRNHAKSADSTCGEDYGGGWWFDRCTQCNLNGEHGVHQRASPAIIWMNWRTGTDKPKSSRMMIR 369
            |..:.|.   |.|...:.||||:..|...|.||::| ..:.|..:.|..|:..........:.||
Mouse  1477 RDNDIAL---SNCALTHHGGWWYKNCHLANPNGKYG-ETKHSEGVNWEPWKGHEFSIPYVELKIR 1537

  Fly   370 P 370
            |
Mouse  1538 P 1538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9593	NP_650493.2	FReD	150..371	CDD:238040	71/225 (32%)
Tnn	NP_808507.2	EGF_2	<142..166	CDD:285248
		EGF_2	169..197	CDD:285248
		EB	181..233	CDD:279949
		EGF_2	233..259	CDD:285248
		fn3	264..332	CDD:278470
		fn3	359..434	CDD:278470
		fn3	444..521	CDD:278470
		FN3	532..608	CDD:214495
		FN3	620..696	CDD:214495
		fn3	708..785	CDD:278470
		fn3	796..875	CDD:278470
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	868..888
		fn3	884..961	CDD:278470
		fn3	972..1049	CDD:278470
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1044..1063
		FN3	1060..1136	CDD:214495
		fn3	1148..1225	CDD:278470
		fn3	1236..1313	CDD:278470	5/21 (24%)
		FReD	1327..1539	CDD:238040	71/225 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910