DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9593 and Tnn

DIOPT Version :9

Sequence 1:	NP_650493.2	Gene:	CG9593 / 41912	FlyBaseID:	FBgn0038365	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001100659.2	Gene:	Tnn / 304913	RGDID:	1306002	Length:	1562	Species:	Rattus norvegicus

Alignment Length:	310	Identity:	89/310 - (28%)
Similarity:	132/310 - (42%)	Gaps:	46/310 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 QVPGRYSSKEDPLAVLSERLNLLLERLNQEERISTNLLELKEWSTKVCQEPSPSQTLPKELTEEK 140
            |:.|...:.:.|..:|.|   :.|:|..|.       .||::....|        |.|..|...|
  Rat  1261 QIDGYILTYQLPNGILKE---VELQRGQQR-------FELQDLEQGV--------TYPVSLVAFK 1307

  Fly   141 DEPK----------VDFYQPAKSDCHELDEGVR--VDGVYRFLVPERNEVQRDLYERYCAFATDG 193
            ...:          ||...|..|||.::.:...  ..|:|...:  ..:..|.: :.||...|||
  Rat  1308 GNQRSRSVSTTLSTVDARFPHPSDCSQVQQNTNAAASGLYTIYL--NGDASRPM-QVYCDMDTDG 1369

  Fly   194 PAWTVIQSRG-GSFDPHENFNRSWDEYRAGFGNLSRDFWFGNEFAHKIL--YRDDHELRIELQEA 255
            ..|.|.|.|. |..|    |.:.|..|..|||:..::||.|.:..|.:.  ....:|:|.:||.|
  Rat  1370 GGWIVFQRRNTGQLD----FFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTTTRYEVRADLQTA 1430

  Fly   256 GEPLDWAEYPLFWLDSESYNYQLSVAGEFRGSLPDALEQHNRMDFSTYDRRRNHAKSADSTCGED 320
            .|.. :|.|..|.:.|....|:||| |::||:..|||..||...|:|:||..:.|.   |.|...
  Rat  1431 NESA-YAVYDFFQVASSKERYKLSV-GKYRGTAGDALTYHNGWKFTTFDRDNDIAL---SNCALT 1490

  Fly   321 YGGGWWFDRCTQCNLNGEHGVHQRASPAIIWMNWRTGTDKPKSSRMMIRP 370
            :.||||:..|...|.||::| ..:.|..:.|..|:..........:.|||
  Rat  1491 HHGGWWYKNCHLANPNGKYG-ETKHSEGVNWEPWKGHEFSIPYVELKIRP 1539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9593	NP_650493.2	FReD	150..371	CDD:238040	72/226 (32%)
Tnn	NP_001100659.2	EGF_2	<142..166	CDD:285248
		EGF_2	169..197	CDD:285248
		EB	181..233	CDD:279949
		EGF_2	233..259	CDD:285248
		fn3	264..332	CDD:278470
		fn3	359..434	CDD:278470
		fn3	444..521	CDD:278470
		FN3	532..608	CDD:214495
		FN3	620..696	CDD:214495
		fn3	708..785	CDD:278470
		fn3	796..875	CDD:278470
		fn3	884..961	CDD:278470
		fn3	972..1049	CDD:278470
		FN3	1060..1136	CDD:214495
		FN3	1148..1224	CDD:214495
		fn3	1236..1313	CDD:278470	15/69 (22%)
		FReD	1327..1540	CDD:238040	72/226 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910