DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9593 and ANGPT1

DIOPT Version :9

Sequence 1:NP_650493.2 Gene:CG9593 / 41912 FlyBaseID:FBgn0038365 Length:382 Species:Drosophila melanogaster
Sequence 2:NP_001137.2 Gene:ANGPT1 / 284 HGNCID:484 Length:498 Species:Homo sapiens


Alignment Length:379 Identity:107/379 - (28%)
Similarity:159/379 - (41%) Gaps:85/379 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 ELVLIRKTLAAQALKLRGLE-----INLHRVLSKVVLLADAVVQVPGRYSSKEDPLAVLSERLNL 97
            |:.|:..:|:...|:.:.|:     :.:|   .|..||...::::.|::..:.|.|....|.|..
Human   160 EIQLLENSLSTYKLEKQLLQQTNEILKIH---EKNSLLEHKILEMEGKHKEELDTLKEEKENLQG 221

  Fly    98 LLERL--------NQEERISTN-------LLELKEWSTKVCQEPSPSQTLPKELTEEKDEPKVDF 147
            |:.|.        .|..|.:||       .|||.:....:....:....|.|....|:::|    
Human   222 LVTRQTYIIQELEKQLNRATTNNSVLQKQQLELMDTVHNLVNLCTKEGVLLKGGKREEEKP---- 282

  Fly   148 YQPAKSDCHEL-DEGVRVDGVYRFLV---PERNEVQRDLYERYCAFATDGPAWTVIQSR-GGSFD 207
                ..||.:: ..|....|:|...:   ||..:|       :|....:|..|||||.| .||.|
Human   283 ----FRDCADVYQAGFNKSGIYTIYINNMPEPKKV-------FCNMDVNGGGWTVIQHREDGSLD 336

  Fly   208 PHENFNRSWDEYRAGFGNLSRDFWFGNEFAHKILYRDDHELRIELQEAGEPLDW------AEYPL 266
                |.|.|.||:.||||.|.::|.||||...|..:..:.|||||      :||      ::|..
Human   337 ----FQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYMLRIEL------MDWEGNRAYSQYDR 391

  Fly   267 FWLDSESYNYQLSVAGEF-RGSLPDALEQHNRMDFSTYDRRRNHAKSADS-----TCGEDYGGGW 325
            |.:.:|..||:|.:.|.. ......:|..|. .||||        |.||:     .|.....|||
Human   392 FHIGNEKQNYRLYLKGHTGTAGKQSSLILHG-ADFST--------KDADNDNCMCKCALMLTGGW 447

  Fly   326 WFDRCTQCNLNG-------EHGVHQRASPAIIWMNWRTGTDKPKSSRMMIRPVN 372
            |||.|...||||       .||    ....|.|..::..:...:|:.|||||::
Human   448 WFDACGPSNLNGMFYTAGQNHG----KLNGIKWHYFKGPSYSLRSTTMMIRPLD 497

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9593NP_650493.2 FReD 150..371 CDD:238040 79/244 (32%)
ANGPT1NP_001137.2 Smc <81..280 CDD:224117 26/122 (21%)
FReD 281..496 CDD:238040 80/252 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2579
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19143
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.910

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