Protein Alignment CG9593 and FGB

DIOPT Version :9

• Sequence 1: NP_650493.2
• Gene: CG9593 / 41912
• FlyBaseID: FBgn0038365
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_005132.2
• Gene: FGB / 2244
• HGNCID: 3662
• Length: 491
• Species: Homo sapiens
• Alignment Length: 518
• Identity: 134/518 - (25%)
• Similarity: 191/518 - (36%)
• Gaps: 189/518 - (36%)

  Fly     2 MKFSLLFLLAWSCVFLGSTGSLNRIGNSDIGFKSLEELVLIRKTLAAQALKLRGLEINLHRVLSK 66
            ||..||.||   ||||..:..:|   :::.||.|                 .||     ||.|.|
Human    15 MKHLLLLLL---CVFLVKSQGVN---DNEEGFFS-----------------ARG-----HRPLDK 51

  Fly    67 VVLLADAVVQVP-----GRYSSK-----------------------EDP-LAVLSERLNLLLERL 102
            ....|.::...|     |.|.::                       .|| |.||......|.|.|
Human    52 KREEAPSLRPAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEAL 116

  Fly   103 NQEER-ISTNLLELKEWSTKVCQEPSPS---QTLPKELTEE-----KDEPKVDFYQPAKSDCHEL 158
            .|:|| |..::.||......|.|..|.|   ..|.|:|.::     ||...|.....::.:.|:|
Human   117 LQQERPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQL 181

  Fly   159 --DEGVRVD-----GVYRFLVPE-RNEVQR---DL------------------------------ 182
              ||.|..:     .|.|.::.. |:::|:   |:
Human   182 YIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIR 246

  Fly   183 -------------------YERYCAFATDGPAWTVIQSR-GGSFDPHENFNRSWDEYRAGFGN-- 225
                               |..||...|:...|||||:| .||.|    |.|.||.|:.||||
Human   247 KGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVD----FGRKWDPYKQGFGNVA 307

  Fly   226 ----------LSRDFWFGNEFAHKILYRDDHELRIELQEAGEPLDW------AEYPLFWLDSESY 274
                      |..::|.||:...::......||.||::      ||      |.|..|.:.:|:.
Human   308 TNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEME------DWKGDKVKAHYGGFTVQNEAN 366

  Fly   275 NYQLSVAGEFRGSLPDALEQ--------------HNRMDFSTYDRRRNHAKSAD--STCGEDYGG 323
            .||:|| .::||:..:||..              ||.|.||||||..:...::|  ..|.::.||
Human   367 KYQISV-NKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGG 430

  Fly   324 GWWFDRCTQCNLNG-------------EHGVHQRASPAIIWMNWRTGTDKPKSSRMMIRPVNP 373
            |||::||...|.||             :||    ....::||||:......:...|.|||..|
Human   431 GWWYNRCHAANPNGRYYWGGQYTWDMAKHG----TDDGVVWMNWKGSWYSMRKMSMKIRPFFP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9593	NP_650493.2	FReD	150..371	CDD:238040	84/328 (26%)
FGB	NP_005132.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..75		10/35 (29%)
		Beta-chain polymerization, binding distal domain of another fibrin	45..47		1/6 (17%)
		Fib_alpha	92..234	CDD:312286	34/141 (24%)
		FReD	237..486	CDD:294064	73/263 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910