DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9593 and Tnc

DIOPT Version :9

Sequence 1:	NP_650493.2	Gene:	CG9593 / 41912	FlyBaseID:	FBgn0038365	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001356140.1	Gene:	Tnc / 21923	MGIID:	101922	Length:	2110	Species:	Mus musculus

Alignment Length:	224	Identity:	70/224 - (31%)
Similarity:	106/224 - (47%)	Gaps:	13/224 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 PAKSDCHE-LDEGVRVDGVYRFLVPERNEVQRDLYERYCAFATDGPAWTVIQSRGGSFDPHENFN 213
            |...||.: :..|....|:|...:   |..:....|.||...:||..|.|...|...   .|:|.
Mouse  1888 PFPRDCSQAMLNGDTTSGLYTIYI---NGDKTQALEVYCDMTSDGGGWIVFLRRKNG---REDFY 1946

  Fly   214 RSWDEYRAGFGNLSRDFWFGNEFAHKILYRDDHELRIELQEAGEPLDWAEYPLFWLDSESYNYQL 278
            |:|..|.||||:...:||.|.:...||..:..:|||::||:.||.. :|.|..|.:......|:|
Mouse  1947 RNWKAYAAGFGDRREEFWLGLDNLSKITAQGQYELRVDLQDHGESA-YAVYDRFSVGDAKSRYKL 2010

  Fly   279 SVAGEFRGSLPDALEQHNRMDFSTYDRRRNHAKSADSTCGEDYGGGWWFDRCTQCNLNGEHGVHQ 343
            .|.| :.|:..|::..||...|||||:   ...||.:.|...|.|.:|:..|.:.||.|.:|.:.
Mouse  2011 KVEG-YSGTAGDSMNYHNGRSFSTYDK---DTDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNN 2071

  Fly   344 RASPAIIWMNWRTGTDKPKSSRMMIRPVN 372
            . |..:.|.:|:......:.:.|.:||.|
Mouse  2072 H-SQGVNWFHWKGHEYSIQFAEMKLRPSN 2099

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9593	NP_650493.2	FReD	150..371	CDD:238040	68/221 (31%)
Tnc	NP_001356140.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	69..91
		EGF_2	222..247	CDD:285248
		EGF_2	345..372	CDD:285248
		EGF_2	377..403	CDD:285248
		EGF_2	408..434	CDD:285248
		EGF_2	468..496	CDD:285248
		EGF_2	504..527	CDD:285248
		EGF_2	533..558	CDD:285248
		EGF_2	592..620	CDD:285248
		FN3	624..710	CDD:238020
		fn3	713..793	CDD:333790
		FN3	804..891	CDD:238020
		fn3	894..976	CDD:333790
		fn3	986..1064	CDD:333790
		fn3	1075..1147	CDD:333790
		fn3	1169..1246	CDD:333790
		fn3	1257..1336	CDD:333790
		fn3	1348..1417	CDD:333790
		fn3	1442..1519	CDD:333790
		fn3	1530..1610	CDD:333790
		fn3	1620..1699	CDD:333790
		fn3	1711..1785	CDD:333790
		fn3	1797..1869	CDD:333790
		Fibrinogen_C	1889..2098	CDD:278572	67/220 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810