DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9593 and Fcna

DIOPT Version :9

Sequence 1:	NP_650493.2	Gene:	CG9593 / 41912	FlyBaseID:	FBgn0038365	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_032021.1	Gene:	Fcna / 14133	MGIID:	1340905	Length:	334	Species:	Mus musculus

Alignment Length:	228	Identity:	77/228 - (33%)
Similarity:	111/228 - (48%)	Gaps:	22/228 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 QPAKSDCHE-LDEGVRVDGVYRFLVPERNEVQRDLYERYCAFATDGPAWTVIQSR-GGSFDPHEN 211
            |.....|.: |..|:.:.|.|...:|:...:     ...|....||..|||.|.| .||.|
Mouse   120 QRGPRSCKDLLTRGIFLTGWYTIHLPDCRPL-----TVLCDMDVDGGGWTVFQRRVDGSID---- 175

  Fly   212 FNRSWDEYRAGFGNLSRDFWFGNEFAHKILYRDDHELRIELQEAGEPLDWAEYPLFWLDSESYNY 276
            |.|.||.|:.|||||..:||.||::.|.:....:.|||::||:......:|:|..|.:..|...|
Mouse   176 FFRDWDSYKRGFGNLGTEFWLGNDYLHLLTANGNQELRVDLQDFQGKGSYAKYSSFQVSEEQEKY 240

  Fly   277 QLSVAGEFRGSLPDALEQHNRMDFSTYDRRRNHAKSADSTCGEDYGGGWWFDRCTQCNLNGEH-- 339
            :|::.....|:..|:|.:||.|.|:|:| :.|.|.|.:  |...:.|.||:..|.|.||||.:
Mouse   241 KLTLGQFLEGTAGDSLTKHNNMSFTTHD-QDNDANSMN--CAALFHGAWWYHNCHQSNLNGRYLS 302

  Fly   340 GVHQRASPAIIWMNWRTGTD---KPKSSRMMIR 369
            |.|:..:..|   ||.||..   ..|.:.|.||
Mouse   303 GSHESYADGI---NWGTGQGHHYSYKVAEMKIR 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9593	NP_650493.2	FReD	150..371	CDD:238040	76/227 (33%)
Fcna	NP_032021.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	47..117
		Collagen	65..106	CDD:189968
		FReD	123..332	CDD:238040	74/223 (33%)
		A domain, contributes to trimerization. /evidence=ECO:0000250	123..162		9/43 (21%)
		B domain, contributes to trimerization. /evidence=ECO:0000250	163..251		34/91 (37%)
		Carbohydrate-binding. /evidence=ECO:0000250\|UniProtKB:O00602	290..292		0/1 (0%)
		P domain. /evidence=ECO:0000250\|UniProtKB:O00602	325..334		4/8 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810