Protein Alignment nsl1 and kansl1

DIOPT Version :9

• Sequence 1: NP_732069.3
• Gene: nsl1 / 41911
• FlyBaseID: FBgn0262527
• Length: 1570
• Species: Drosophila melanogaster
• Sequence 2: XP_031750085.1
• Gene: kansl1 / 100485168
• XenbaseID: XB-GENE-5760844
• Length: 906
• Species: Xenopus tropicalis
• Alignment Length: 1318
• Identity: 254/1318 - (19%)
• Similarity: 417/1318 - (31%)
• Gaps: 547/1318 - (41%)

  Fly   238 PEEH-----VAPPSVPVPVQEAPNTPTRPQAPPS----------------AHLESPQPARTQ--- 278
            |:.|     :||||..:|:.|.......|.|.|.                |.:..|....:|
 Frog    13 PDAHNLHFKLAPPSSSLPLGEVNGGSLPPPAAPDLVASYCGTISKDQLKLAGVLGPGSILSQSLC 77

  Fly   279 --QQSIQQMTPQSTTSSNNFLKDGAAGAVLEDQDIEEVLKALKTFDGGHVNPDTICEFFDEVWEE 341
              :.||.::..:......|..:.|..|.:  :...:::.|.......||..|:.      |.|.:
 Frog    78 RGRPSILEINLEELRGITNSGRGGQGGPL--NGLAKKLNKPAVDRPPGHAVPNL------ETWVK 134

  Fly   342 AAPAAPLPPAPPENVVDVPGAKPSCSGILVSGSNISQPNVIIKQEQRPWQESHAELEQQQHVISR 406
            ....:|..|...:....:| .:|.      ||:.:   ..::::        |.|:|::    :|
 Frog   135 TQAVSPESPTAAQEEKGIP-VEPG------SGARL---QALLRR--------HGEMEER----AR 177

  Fly   407 RIEFLLRRMRKLQARAMCRHASEEVVGIMEWSARSSHKAPVPARSSTLTEQEATVLSIVSGRPSS 471
            |::   :|:|.:||:.:.||..:::.|::..|...:.::| .:|.:.||.:
 Frog   178 RLQ---KRLRLVQAKQVERHLHQQLGGLVGASINRTVESP-RSRLTVLTRK-------------- 224

  Fly   472 TFWEEQNKHPLPASQMSNVIRHIATAAKHQQICHSASGSSATLAPSSSWYNSCNSSALPMKRPRK 536
                                     |...:::....:||.|.|..::               |..
 Frog   225 -------------------------AEAQRRVEEEGAGSDAFLKEAA---------------PEL 249

  Fly   537 NQLDASVATGATPTAPAPGAVTSRQAAGTTGSATGSNTPRADDIVPGYDTYVTNELTHVSGLLHT 601
            .:|  |::.||.
 Frog   250 AKL--SLSGGAA----------------------------------------------------- 259

  Fly   602 ELREVQNAIDSDATESSSGGES--ADEMVTYNNNQQLSLPITRRAVWRYSRDRAAIALRWSWLCS 664
             ||..:...|||||||||||:|  .:|.:...:.::..:|:.||..|.::::||.:..||:||.:
 Frog   260 -LRACELGFDSDATESSSGGDSDIEEEELNRADTRRNHMPLKRRCEWSWAQERADVVSRWNWLQA 323

  Fly   665 QLTDLEMKIRQHSDLYMDLTQSKGEI------------------QLESTAKTSP----------- 700
            .::|||.:||||:|.|..|...||::                  .|:|...:||
 Frog   324 HVSDLEYRIRQHTDFYRQLRSGKGQVVLGEACPSETAGEPLRSSLLDSRTSSSPSPDAERRADSS 388

  Fly   701 -----SLAQPANGI-------------------------KEEPGSDYLCSRARPLVLSEFRKRKL 735
                 ||.:|.|||                         ..:|.|..:|:|.||||..  ::|::
 Frog   389 TTEAKSLQRPINGIVNMLPPVLPTRSGSDTQELALSKPLSPQPDSTCVCARTRPLVTC--KRRRI 451

  Fly   736 FQTTNMHTISKKAARPSNIKCGCQWPQVPCTLCTGRTDPTAPRDLVETMMPQNRVALLDAGYHPV 800
            .:...:..::||..|.:...|..   ...|.:|.....|:|.....:.:  ..|:||||...|||
 Frog   452 VRPDRLLPLNKKVQRGTPHVCEV---SSSCVMCASLPGPSAEIQYSDPL--AERLALLDPSIHPV 511

  Fly   801 LSFASDVSQSVHLEAVARQPDWQYRVMRSQPKAIVKAMWKAERETIASGGVGGQGGSRRSGDAAK 865
            |||..|:..|:.|.::.|    .::..||  |:|.|...:...:..::..:  ..|.|..|....
 Frog   512 LSFPDDIPTSLRLLSLLR----SHKQDRS--KSIKKLKLRPLNQLPSTPEL--PRGDRLQGAPNV 568

  Fly   866 RRYIRRKERNNNSNKEAGSGAKAAAVAAGGAGGNGSSSVGGGDSGNGTGTATTSSSTTPTTTPLV 930
            .|....:..:....:......:                           |.....|....:.|||
 Frog   569 HRVSHHRPADLTPKQPLEPPLR---------------------------TLKIDRSLISRSDPLV 606

  Fly   931 ANTAARGKRQ----PQHPTGANSSSSLWPDSRQRQRQRHHSPSSTSISALSGAKKARKSATNSSS 991
            .::|...||:    |....||           |:......||:..|.|.:|.....|:.:.:|..
 Frog   607 TSSAPHVKRRQLGVPDRNAGA-----------QQVDPSISSPAPVSASPVSQPPLIRQLSASSEG 660

  Fly   992 SNSTQQQQNHHGTKINNHHLNGYGDQWGEQSRSRRNSSPSNSHKNERTSERRVRPIYDINNIVIP 1056
            ..|:                      :.....:||               ||....|||||||||
 Frog   661 QISS----------------------YSASVAARR---------------RRTESSYDINNIVIP 688

  Fly  1057 YSMLAQSKMEIIPYKEIPIPKWRIVDSDNDKGKHSSDESMERKLSNGCVASKSEELAKQQLPPPP 1121
            .|:.|.:::|.:.||||..|.||:|
 Frog   689 MSVAATTRVERLQYKEILTPSWRVV---------------------------------------- 713

  Fly  1122 DQDQEQPALQPPKVNGLKENQAVKHNNNNNTNNNNNKNGLVNGNAKKDELKAAEDHDTQSKEDDD 1186
                                                                   |.|
 Frog   714 -------------------------------------------------------HIT------- 716

  Fly  1187 PKEKVVKPKLNGNLIKNPIDKTAETQDKIAQPAPEPPLPKRPKLETPTSNEVTKANGQLVQQQLE 1251
                             |:                          ||.:.|
 Frog   717 -----------------PV--------------------------TPNNEE-------------- 724

  Fly  1252 SRESEEEPQHVDEDLSDEAFIMRHQRALLEERRRFETFLKFPWSTRSRANRRVDSRAESSGAN-- 1314
              :|||.     |||||.||...|.:...:||.|:.:.:. |....||.:|..:|....|...
 Frog   725 --DSEEL-----EDLSDAAFSELHAKCEEQERARWLSSVP-PQRRGSRTHRTSESSVTPSAGTRP 781

  Fly  1315 -TPDPASPAPHLGGPGHDN---ESIP--SPLAYPLDAFNESGELLTGGQARQARRRTTSSKLKDQ 1373
             ||.|:||         |.   ::||  |||         |.::|:......:|.   :|:|..:
 Frog   782 LTPQPSSP---------DTGSWQAIPDFSPL---------SPDVLSAPPTPTSRE---TSRLLSE 825

  Fly  1374 LERRSTTPDLRESYTVMPSPFEPLNFPLSDEVYQRLLAETYAPPRSMTVSKRAKSKSISSNCDGG 1438
            ..:.|.:...||...|  .|:|..|||||           |:|.|.:|           ..|:
 Frog   826 ETQSSISDSGREELAV--QPWERRNFPLS-----------YSPKRELT-----------GPCE-- 864

  Fly  1439 NTFTGGSGSRRSSKCKIK 1456
            .|..||:...|...|..|
 Frog   865 PTDWGGARPPRRPSCSSK 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nsl1	NP_732069.3	PEHE	1250..>1325	CDD:291924	25/77 (32%)
kansl1	XP_031750085.1	PEHE	705..828	CDD:405867	47/310 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006248
OrthoInspector	1	1.000	-	-		otm47636
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4917
SonicParanoid	1	1.000	-	-		X4531
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.030