Protein Alignment Uros2 and UROS

DIOPT Version :10

• Sequence 1: NP_650489.1
• Gene: Uros2 / 41908
• FlyBaseID: FBgn0038361
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_001310965.1
• Gene: UROS / 7390
• HGNCID: 12592
• Length: 292
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 74/266 - (27%)
• Similarity: 105/266 - (39%)
• Gaps: 45/266 - (16%)

  Fly     9 VILLKVPSSDDF----YGSALRSHNLDPIFITPSHFVFKNLKQLQAKLHEPHKYAGIIFASPRCV 69
            |:|||....||.    |...|..:.|:...|....|.|.:|.....||..|..|.|:||.|||.|
Human     3 VLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLIFTSPRAV 67

  Fly    70 QAVN---EALGKT-----PLPSCWRALHNYSLGKNTHSAAWITFQNLPTLGDHAVNANNLCDLIV 126
            :|..   |...||     .|...|.|...|.:|..|  |:.::...|.|.|:...||..|.:.|.
Human    68 EAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNAT--ASLVSKIGLDTEGETCGNAEKLAEYIC 130

  Fly   127 ETFGPKRDLPLLMPCGNGVGQTLRLRLVAQGFRVDACEVYESRSHPDFVNQMRHALKFKRM-ETI 190
            ..  ....||||.||||...:.|...|..:|..:::..||::.:||.....:......:.: .:|
Human   131 SR--ESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNLNSYYSQQGVPASI 193

  Fly   191 VFFGPSSVRSSL----EFFGNYNVSLKD----------------RK--------LIAVGSGTRKA 227
            .||.||.:..||    |..|:....:|.                ||        ..|:|..|.:|
Human   194 TFFSPSGLTYSLKHIQELSGDNIDQIKTQGPQHPKKNCLQLEPLRKDCTDTAVMFAAIGPTTARA 258

  Fly   228 MEESGI 233
            :...|:
Human   259 LAAQGL 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uros2	NP_650489.1	HemD	9..251	CDD:119440	74/266 (28%)
UROS	NP_001310965.1	HemD	3..282	CDD:119440	74/266 (28%)