Protein Alignment CG5614 and OFD1

DIOPT Version :10

• Sequence 1: NP_650487.1
• Gene: CG5614 / 41906
• FlyBaseID: FBgn0038359
• Length: 358
• Species: Drosophila melanogaster
• Sequence 2: XP_047298539.1
• Gene: OFD1 / 8481
• HGNCID: 2567
• Length: 1019
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 72/383 - (18%)
• Similarity: 142/383 - (37%)
• Gaps: 99/383 - (25%)

  Fly    41 ILQMIRGQQNKSKVQALTGGSNQSEDHSLVKLINQ--MIMEFL-DWFGYKHTMETFRMET-GENV 101
            :||:|:.....|..::|..||::.         ||  .:|.|| :...|....|:..||| ..:.
Human   118 LLQLIKINPTSSLYKSLVSGSDKE---------NQKGFLMHFLKELAEYHQAKESCNMETQTSST 173

  Fly   102 ANRREMEQSLHIT--------PESKDFPLLAQLVMRDWKFGVQ---------------------- 136
            .||..:.:.|.:.        |:...|..| ::.:.::|..::
Human   174 FNRDSLAEKLQLIDDQFADAYPQRIKFESL-EIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKI 237

  Fly   137 -----KGGSKKLVQLPDPME---------------ATVQRSRK---------------LVQELKV 166
                 |...|:|....:..|               :|::|..|               |::::.:
Human   238 KMEAKKKYEKELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDL 302

  Fly   167 MRAQKSEVNQ--------GRLVQNNRKLITNNTFTKGLTPKSI-STPPRSIKNENPKSYVDSSES 222
            :|.:::|:.|        .:|.:...|.||.....:....||. .|..|.:|||..|..::..:.
Human   303 LRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLELKDD 367

  Fly   223 DVLESD-YSEEESEDSDAYKDIPDRQIFIDDLPPEGKYAPNYGEEGPFEGKQNQANERDNIPSTS 286
            .::.:: ..|:|.::.:....:.:..|.|:....|...:.|..:|...|.:..:|...    :.:
Human   368 YIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVKAQSL----AIT 428

  Fly   287 RKQHFSRKPETESSD----SDDKPSISGINKVSRQDYWNSPRGVQLRNKNTL-KPEEE 339
            ::.|...:...|.||    .::|..:...||:.:|....| |...||..|.| :|..|
Human   429 KQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEES-RNENLRLLNRLAQPAPE 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5614	NP_650487.1	LisH	71..98	CDD:128913	10/30 (33%)
OFD1	XP_047298539.1	LisH_2	82..108	CDD:464992
		Smc	<280..>563	CDD:440809	42/211 (20%)