DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5614 and Cep20

DIOPT Version :9

Sequence 1:	NP_650487.1	Gene:	CG5614 / 41906	FlyBaseID:	FBgn0038359	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_079621.1	Gene:	Cep20 / 66086	MGIID:	1913336	Length:	174	Species:	Mus musculus

Alignment Length:	108	Identity:	29/108 - (26%)
Similarity:	52/108 - (48%)	Gaps:	15/108 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 IKSQLEKNGTMAALRSEMHVKILQMIRGQQNKSKVQALTGGSNQSEDHSLVKLINQMIMEFLDWF 84
            :|..|||.|.:..|::.:..::...:...:.          ...|..|..: |||::|.|:|::.
Mouse    11 LKDTLEKRGVLGHLKARIRAEVFNALDDDRE----------PRPSLSHENL-LINELIREYLEFN 64

  Fly    85 GYKHTMETFRMETGENVA--NRREMEQSLHITPESKD--FPLL 123
            .||:|......|:|:.|.  :|:.:.:.|:...||||  .|||
Mouse    65 KYKYTASVLIAESGQPVVPLDRQFLIRELNAFEESKDNSIPLL 107

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5614	NP_650487.1	FOP_dimer	<71..129	CDD:150162	21/57 (37%)
CG5614	NP_650487.1	LisH	71..97	CDD:285685	9/25 (36%)
Cep20	NP_079621.1	Necessary and sufficient for homooligomerization and localization to centrosomes and pericentriolar satellites. /evidence=ECO:0000250	1..104		26/103 (25%)
		FOP_dimer	43..113	CDD:150162	23/66 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..174
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2B269
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104918
Panther	1	1.100	-	-	LDO	PTHR15431
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.860