Protein Alignment Ttc26 and ift56

DIOPT Version :10

• Sequence 1: NP_650486.1
• Gene: Ttc26 / 41905
• FlyBaseID: FBgn0038358
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_001096401.1
• Gene: ift56 / 100125003
• XenbaseID: XB-GENE-1002214
• Length: 554
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 300/576 - (52%)
• Similarity: 405/576 - (70%)
• Gaps: 43/576 - (7%)

  Fly     1 MILSRGKTDSASSRNASGGPGSGLGV------GRQARKTPAPASLEDFIIRRDYTGARAFLEFAN 59
            |:|||.|            |..|..|      .::.:|.|   .|::.:.:||:|||...|||..
 Frog     1 MMLSRAK------------PAVGNEVQQIDKKKKKGKKVP---RLDELLAQRDFTGAITLLEFKR 50

  Fly    60 DDEDEEEGAHGSKQSQVDQWIAFCNFHLGDYQQALAQYKAI-QQGSSTPDGKLDLNLAVCMFYLG 123
            ...:.||        ..:.||.:|:||||||:::|..:||: ||....||  :.:|||...|:||
 Frog    51 QVGESEE--------DTELWIGYCSFHLGDYKRSLEVFKALSQQEGCNPD--VWVNLACTSFFLG 105

  Fly   124 LYEEAQQLMANAADNPLKQRLLFHLAHKLGNEEEWSQLQEELQDSSSLEQQLSLASMHYMRAHYQ 188
            :|:||.:....|..:.|:.|||||||||..:|:......:.|||  .:|.||||||:||||:|||
 Frog   106 MYKEADEAANKAPKSRLQNRLLFHLAHKFNDEKRLMVFHQNLQD--VIEDQLSLASIHYMRSHYQ 168

  Fly   189 EAIDVYKRVLVDNKEYQAINVYLALCFYKLDYYDMSQEVLDVYLSQHGDSTIAINLKACNRFRLF 253
            ||||:|||:|::|:::.|:|||:|||:|||||||:|||||.|||.|..|||||:||||||.|||:
 Frog   169 EAIDIYKRILLENRDFLALNVYVALCYYKLDYYDVSQEVLAVYLQQVPDSTIALNLKACNHFRLY 233

  Fly   254 NGRVAEQEIKNIADNGT----FGADLLRHNLVVFRNGEGALRVLPGLLNIIPEARLNLAIYYLKQ 314
            ||:.||.|:|.:.|:.:    |..:|::|||||||.|||||:|||.|:::||||||||.||||:|
 Frog   234 NGKAAEAELKGLMDSTSSPIEFAKELIKHNLVVFRAGEGALQVLPPLVDVIPEARLNLVIYYLRQ 298

  Fly   315 GDVQEAHALMKELQPTSPHEYILKGVVHAALGQQLGSKEHIKTAQQNLHLVGSSATECDTIPGRQ 379
            .|||||..|:|:|:|::|.||||||||:|:|||:|||::|:|.|||...|||.||:|||||||||
 Frog   299 DDVQEAFNLIKDLEPSTPQEYILKGVVNASLGQELGSRDHLKIAQQFFQLVGGSASECDTIPGRQ 363

  Fly   380 SMASAFFLYEQFEEVLVYMNSIRSYFVNDDVFNYNFAQAKCATGYYKEAEELLMQISDMDIKNQH 444
            .|||.|||..||::||:|:|||:|||.|||.||:|:||||.|.|.||||||:.:.|.:..|||.:
 Frog   364 CMASCFFLLRQFDDVLIYLNSIKSYFYNDDTFNFNYAQAKAAVGNYKEAEEVFLLIQNEKIKNDY 428

  Fly   445 TYCMILAKCHIHCGHPELAWNVFITRDTNAEAFILLQLIANECYKCAEFWVAAKAFDMLEKLDPS 509
            ||...||:|:|....|.:||.:::..:|:.|:|.|||||||:|||...|:.||||||:||:||||
 Frog   429 TYLSWLARCYIMNKKPRMAWELYLKMETSGESFSLLQLIANDCYKMGHFYYAAKAFDILERLDPS 493

  Fly   510 PENWEGKRGACAGVLFALCTKAQRGR-PGGGISEVIGILRDSSNSQAEAMIKTIRK 564
            ||.||||||||.|:...:..    || |...:.||:.:||.:.|:|.|.:|:.::|
 Frog   494 PEYWEGKRGACVGIFQMILA----GREPKETLREVLNLLRSTGNTQVEYIIRILKK 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ttc26	NP_650486.1	LapB	<85..244	CDD:442196	88/159 (55%)
		TPR repeat	107..133	CDD:276808	11/25 (44%)
		BepA	<301..360	CDD:443813	40/58 (69%)
ift56	NP_001096401.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		8/33 (24%)
		TPR 1	57..90		15/40 (38%)
		TPR repeat	58..86	CDD:276809	12/27 (44%)
		LapB	<68..246	CDD:442196	103/181 (57%)
		TPR repeat	91..117	CDD:276809	11/27 (41%)
		TPR 2	92..125		12/34 (35%)
		TPR repeat	129..178	CDD:276809	30/50 (60%)
		TPR 3	151..184		23/32 (72%)
		TPR repeat	184..214	CDD:276809	22/29 (76%)
		TPR repeat	219..243	CDD:276809	17/23 (74%)
		BepA	365..492	CDD:443813	71/126 (56%)
		PPR repeat	427..457	CDD:276811	9/29 (31%)
		PPR repeat	459..490	CDD:276811	21/30 (70%)
		TPR 4	468..501		23/32 (72%)