DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5404 and YPR003C

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_015328.1	Gene:	YPR003C / 856111	SGDID:	S000006207	Length:	754	Species:	Saccharomyces cerevisiae

Alignment Length:	588	Identity:	123/588 - (20%)
Similarity:	258/588 - (43%)	Gaps:	109/588 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 HVPVFQWLPLYSTE--WGIDDFIAGITLGLTIIPESMA-CALLAGLPARYGLCSAFIGPLIYMVF 109
            ::|.|.|||.|:..  ||  |.||||::....||.::: ...:|.:|...||.|..|.|.:|.:.
Yeast   104 YLPCFSWLPEYTFNKLWG--DVIAGISVASFQIPLALSYTTSIAHVPPLCGLYSLAISPFVYGIL 166

  Fly   110 GSIDKVIIGPTSLVALVSVQFTVGRPIE-------------FAFLLTFLSGIVQIIMGTMRMGFI 161
            ||:.::|:||.|.::||     ||:.:|             .:.::||:||.:.:..|..|.||:
Yeast   167 GSVPQMIVGPESAISLV-----VGQAVESITLHKENVSLIDISTVITFVSGTILLFSGISRFGFL 226

  Fly   162 FEFISMPVIKAF-SSATAILVIESQLKVLLGIKYLVA-------GLMNSVGMLSSRIEESNMADL 218
            ...:|..:::.| ||...:::|.|.:..|...|:||:       .....:.::.....:.::...
Yeast   227 GNVLSKALLRGFISSVGLVMIINSLISELKLDKFLVSLPQHYHTPFEKILFLIDYAPAQYHIPTA 291

  Fly   219 IMGVCAIVFLLLLELLDRVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIVSFIWIQKCGQVPYA 283
            |...|.::.|.|..||.|        |:::.....:......|:|::..::|..:..|
Yeast   292 IFSGCCLIVLFLTRLLKR--------KLMKYHKSAIFFPDILLVVIVTILISMKFNLK------- 341

  Fly   284 LSKNALSTLPNFTVPSF----HIETAERNYSIWEVLKELNIGIIVIPIVGILTNISIGK---LTP 341
             .:..:|.:.:|::.:|    :..|..|.    :::.:|....:::.::|...:.:..|   .|.
Yeast   342 -HRYGISIIGDFSMDNFDELKNPLTRPRR----KLIPDLFSASLIVAMLGFFESTTASKSLGTTY 401

  Fly   342 KGLVDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLALSYLSP 406
            ...|.:|:||:.:|..|:..|...|:|:.|.:.|..|:...|.::.|:.:::|:|.|:.::.|..
Yeast   402 NLTVSSNRELVALGFMNIVISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITLITMNLLLQ 466

  Fly   407 YFNYIPEATLAAILICSIFTLL-----DFKLPMRLWRDSKRDFATWLLCFCVSVLFGVEVGLFVS 466
            :.:|||...|:.|......:||     |.|..:|....|  :...:.:.||.::.:.:|.|:.:.
Yeast   467 FVHYIPNCVLSVITTIIGISLLEEVPGDIKFHLRCGGFS--ELFVFAVTFCTTIFYSIEAGICIG 529

  Fly   467 IVVTALHLLFLWARPEIRV----------------------------KIEQLDEMQYIRVTPSNG 503
            .|.:.::::...|:..|::                            ..|:::....:|:  ...
Yeast   530 CVYSIINIIKHSAKSRIQILARVAGTSNFTNLDDYMMNMKRNSLDVEGTEEIEGCMIVRI--PEP 592

  Fly   504 IYFPAINYLRERV--------------LKACEQADFRITVVIDGQRISGMDYTAAQGISKLSSDL 554
            :.|.....|::|:              .|:....|....|:.|...::.:|.:|||.:.::.:..
Yeast   593 LTFTNSEDLKQRLDRIERYGSSKIHPGRKSLRSKDSIKYVIFDLGGMTSIDSSAAQVLEEIITSY 657

  Fly   555 CRQ 557
            .|:
Yeast   658 KRR 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	122/584 (21%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	11/69 (16%)
YPR003C	NP_015328.1	SUL1	99..732	CDD:223732	123/588 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820