DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5404 and SUL1

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_009853.3	Gene:	SUL1 / 852597	SGDID:	S000000498	Length:	859	Species:	Saccharomyces cerevisiae

Alignment Length:	471	Identity:	130/471 - (27%)
Similarity:	235/471 - (49%)	Gaps:	58/471 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 PVFQWLPLYSTEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSIDK 114
            |:.:|.|.|:..||..|.:||||:|..::|:||:.|.:|.|...|||.|:|||..||.:|.:...
Yeast   108 PIIKWFPHYNFTWGYADLVAGITVGCVLVPQSMSYAQIASLSPEYGLYSSFIGAFIYSLFATSKD 172

  Fly   115 VIIGPTSLVALVSV-------------QFTVGRPIEFAFLLTFLSGIVQIIMGTMRMGFIFEFIS 166
            |.|||.::::|.:.             |..|..|| .|..|..|.|||...:|.:|:||:.|.||
Yeast   173 VCIGPVAVMSLQTAKVIAEVLKKYPEDQTEVTAPI-IATTLCLLCGIVATGLGILRLGFLVELIS 236

  Fly   167 MPVIKAFSSATAILVIESQLKVLLGIKYLVAGLMNSVGMLSSRIEE--SNMADLIMGVCAIVFLL 229
            :..:..|.:.:|..:|..|:..|:|...||.....:..::.:.::.  :...|.:.|:..:|.|.
Yeast   237 LNAVAGFMTGSAFNIIWGQIPALMGYNSLVNTREATYKVVINTLKHLPNTKLDAVFGLIPLVILY 301

  Fly   230 L---------LELLDRVANNEKR--NKILRIFCRYLSTSRNTLIVLIAAIVSFIW---------- 273
            :         :.|.||...|:.:  |: |:.|..|....||.:::::...:|  |
Yeast   302 VWKWWCGTFGITLADRYYRNQPKVANR-LKSFYFYAQAMRNAVVIVVFTAIS--WSITRNKSSKD 363

  Fly   274 --IQKCGQVPYALSKNALSTLPNFTVPSFHIETAERNYSIWEVLKELNIGIIVIPIVGILTNISI 336
              |...|.||..|::..:..:|:..:.:              :..|:...|||:.:..|..:.|.
Yeast   364 RPISILGTVPSGLNEVGVMKIPDGLLSN--------------MSSEIPASIIVLVLEHIAISKSF 414

  Fly   337 GKLTPKGLVDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLAL 401
            |::....:| .:|||:.:|:.|:.|:...:.|::|:|:|.|:...|.:|||.:.::.|..|||||
Yeast   415 GRINDYKVV-PDQELIAIGVTNLIGTFFHSYPATGSFSRSALKAKCNVRTPFSGVFTGGCVLLAL 478

  Fly   402 SYLSPYFNYIPEATLAAILICSIFTLL-DFKLPMRLWRDSKRDFATWLLCFCVSVLFGVEVGLFV 465
            ..|:..|.:||:|||:|::|.::..|| .:|.....|:.:..|..::::...::|...:|.|::.
Yeast   479 YCLTDAFFFIPKATLSAVIIHAVSDLLTSYKTTWTFWKTNPLDCISFIVTVFITVFSSIENGIYF 543

  Fly   466 SIVVTALHLLFLWARP 481
            ::..:...||...|.|
Yeast   544 AMCWSCAMLLLKQAFP 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	130/471 (28%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913
SUL1	NP_009853.3	SUL1	102..784	CDD:223732	130/471 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341580
Domainoid	1	1.000	211	1.000	Domainoid score	I497
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I705
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		mtm9191
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
TreeFam	1	0.960	-	-
	11	10.850