DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5404 and AST91

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_173722.1	Gene:	AST91 / 838917	AraportID:	AT1G23090	Length:	631	Species:	Arabidopsis thaliana

Alignment Length:	642	Identity:	166/642 - (25%)
Similarity:	292/642 - (45%)	Gaps:	114/642 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 PRMNKWKRRLHRHVPVFQWLPLYSTEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAF 100
            |...|..|......|:.||.|.||......|.::|:|:....||:.::.|.||.||...||.|:|
plant    39 PNRTKLIRAAQYIFPILQWCPEYSFSLLKSDVVSGLTIASLAIPQGISYAKLANLPPIVGLYSSF 103

  Fly   101 IGPLIYMVFGSIDKVIIGPTSLVALVSVQF------TVGRPIEF---AFLLTFLSGIVQIIMGTM 156
            :.||:|.|.||...:.:||.|:.:|:....      .|..|:.|   ||..||.:|:.|..:|.:
plant   104 VPPLVYAVLGSSRDLAVGPVSIASLILGSMLRQQVSPVDDPVLFLQLAFSSTFFAGLFQASLGIL 168

  Fly   157 RMGFIFEFISMPVIKAFSSATAILVIESQLKVLLGIKYLVAGLMNSVGMLSSRIEESN---MADL 218
            |:|||.:|:|...:..|....||:|...|||.||||.:.... |:.|.:|||..:.:|   ...:
plant   169 RLGFIIDFLSKATLIGFMGGAAIIVSLQQLKGLLGITHFTKH-MSVVPVLSSVFQHTNEWSWQTI 232

  Fly   219 IMGVCAIVFLLLLELLDRVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIVSFIW------IQKC 277
            :||||.::|||....|     :.|:.|:.     ::|.....|.|:::.::.|::      |...
plant   233 VMGVCFLLFLLSTRHL-----SMKKPKLF-----WVSAGAPLLSVIVSTLLVFVFRAERHGISVI 287

  Fly   278 GQVPYALSKNALSTLPNFTVPSFH-------IETAERNYSIWEVLKELNIGIIVIPIVGILTNIS 335
            |::|..|:.      |::.:..||       .:|.                 :|..||.:...|:
plant   288 GKLPEGLNP------PSWNMLQFHGSHLALVAKTG-----------------LVTGIVSLTEGIA 329

  Fly   336 IGKLTPKGL----VDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGII 396
            :|: |...|    ||.|:|::.:||.|:.||......::|||:|.|::...|.:|.::|:.:.:.
plant   330 VGR-TFAALKNYHVDGNKEMIAIGLMNVVGSATSCYVTTGAFSRSAVNNNAGAKTAVSNIVMSVT 393

  Fly   397 VLLALSYLSPYFNYIPEATLAAILICSIFTLLDFKLPMRLWRDSKRDFATWLLCFCVSVLFGVEV 461
            |::.|.:|.|.|.|.|...|.||::.::..|:|......:|:..|.||...|..|...:...|:.
plant   394 VMVTLLFLMPLFEYTPNVVLGAIIVTAVIGLIDLPAACHIWKIDKFDFLVMLCAFFGVIFLSVQN 458

  Fly   462 GLFVSIVVTALHLLFLWARPEIRV-----------KIEQLDEMQ----YIRVTPSNGIYFPAINY 511
            ||.:::.::...:|....||::.:           .:....|.|    ::.::..:.:.|...||
plant   459 GLAIAVGLSLFKILMQVTRPKMVIMGNIPGTDIYRDLHHYKEAQRIPGFLVLSIESPVNFANSNY 523

  Fly   512 LRERV---LKACEQADFRIT------VVIDGQRISGMDYTAAQGISKLSSDLCRQADASSSTLLI 567
            |.||.   ::.||:.:.:..      ::::...:||:|........:|     ::..|.....|:
plant   524 LTERTSRWIEECEEEEAQEKHSSLQFLILEMSAVSGVDTNGVSFFKEL-----KKTTAKKDIELV 583

  Fly   568 ----LFRFPEHLQRLIDNTDNLVFCESENKVKEFLTQESLRNGYINLKEHIRASIDL 620
                |....|.|||             .::.|||:..|.|   ::.:.|.: ||:.|
plant   584 FVNPLSEVVEKLQR-------------ADEQKEFMRPEFL---FLTVAEAV-ASLSL 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	147/559 (26%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	12/64 (19%)
AST91	NP_173722.1	sulP	53..617	CDD:273284	159/619 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
OMA	1	1.010	-	-		QHG55446
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		mtm1058
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.970