DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5404 and slc26a6

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_001072916.2	Gene:	slc26a6 / 780378	XenbaseID:	XB-GENE-919879	Length:	735	Species:	Xenopus tropicalis

Alignment Length:	589	Identity:	149/589 - (25%)
Similarity:	277/589 - (47%)	Gaps:	130/589 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GAISKPA------SEAGK---APR--------MNKWKRRLH-----------RHVPVFQWLPLYS 59
            ||:..||      |||..   |||        :.:.|:|:.           :.:|:..|:|.|.
Frog    13 GAVMDPAARQLVLSEAELEEIAPRSQRVGPSTLARMKKRIRCSGSIAKSLLLKFIPILGWIPRYP 77

  Fly    60 T-EWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFG----------SID 113
            . ||.:.|.:||:::|:..:|:.:|.|||||:|..|||.|:|...|:|.:||          ::.
Frog    78 VREWLLGDIVAGLSVGIIQLPQGLAYALLAGVPPVYGLYSSFFPVLLYAIFGTSRHISPGTFAVI 142

  Fly   114 KVIIG-------PTSLV------ALVSVQFTVGRPIEFAFLLTFLSGIVQIIMGTMRMGFIFEFI 165
            .|::|       |:.|.      .|:::.......:..|..||||.|:.||::|.:::||:..::
Frog   143 SVMVGSVTESLVPSELYTLPGNETLINITARDNDRVAVASALTFLVGLFQIMLGLVQVGFVVTYL 207

  Fly   166 SMPVIKAFSSATAILVIESQLKVLLGIKY--------LVAGLMNSVGMLSSRIEESNMADLIMGV 222
            |.|:|:.::||.||.|..||:|.:||::.        |:..::|    |.:::.|:|:|.|::|.
Frog   208 SEPLIRGYTSAAAIHVTVSQMKSVLGVQISQRSHPLSLIYAIVN----LCAKLPETNIASLLIGG 268

  Fly   223 CAIVFLLLLELLDRVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIVSF-------IWIQKCGQV 280
            .||..|.:::.|     |:|.:..:|     :......:.:::|..:|:       ..:...|::
Frog   269 IAITVLFVVKFL-----NDKYSSKIR-----MPIPIELITLIVATGISYGANLNQVYGVDIVGEI 323

  Fly   281 PYALSKNALSTLPNFTVPSFHIETAERNYSIWEVLKELNIGIIVIPIVGILTNISIGKL--TPKG 343
            |..:.   ...:||.::.:..:..|                 ..|.:|.....||:.|:  ...|
Frog   324 PTGMK---APMVPNASIFASVVGNA-----------------FAIAVVVYAFTISLAKMFAVKHG 368

  Fly   344 L-VDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLALSYLSPY 407
            . ||:||||:.:||.|..||..|......|.:|..:..:.|..:.:|:....:::|:.:......
Frog   369 YNVDSNQELIALGLSNSIGSFFQCFTIGTAMSRSLVQESTGGHSQVASAVSSLVILIIILRAGEL 433

  Fly   408 FNYIPEATLAAILICSI------FTLLDFKLPMRLWRDSKRDFATWLLCFCVSVLFGVEVGLFVS 466
            |..:|:|.|||:::.::      ||    .:|| |||.:|.|...|::.|..::|..:::||.||
Frog   434 FQTLPKAILAAVVVVNLKGIYKQFT----DVPM-LWRSNKIDLLVWVVTFLATILLNLDIGLAVS 493

  Fly   467 IVVTALHLLFLWARPEIRV--------------KIEQLDEMQYIRVTPSN-GIYFPAINYLRERV 516
            :..:.|.::|...:|...:              :.:|:.|:|.|::..|: .:||...|...|.|
Frog   494 VAFSLLTVIFRTQKPHYSILGKVDNTDIYRDVAQFDQVTEIQGIKIFRSSCTLYFANANLYAESV 558

  Fly   517 LKAC 520
            .:.|
Frog   559 KRMC 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	137/534 (26%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	7/24 (29%)
slc26a6	NP_001072916.2	sulP	68..711	CDD:273284	137/534 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910