Protein Alignment CG5404 and slc26a4.3

DIOPT Version :10

• Sequence 1: NP_650482.1
• Gene: CG5404 / 41901
• FlyBaseID: FBgn0038354
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_001107135.1
• Gene: slc26a4.3 / 779605
• XenbaseID: XB-GENE-950380
• Length: 778
• Species: Xenopus tropicalis
• Alignment Length: 654
• Identity: 161/654 - (24%)
• Similarity: 280/654 - (42%)
• Gaps: 148/654 - (22%)

  Fly    50 PVFQWLPLYS-TEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSID 113
            ||..|||.|. .||.::|.|:|::.||....:.:|.||||.:|..|||.|:|...|.|...|:..
 Frog    66 PVLDWLPKYRWKEWFVNDLISGVSTGLVGTLQGLAFALLAAVPVGYGLYSSFFPILTYFFLGTSK 130

  Fly   114 KVIIGPTSLVALV--SVQFTVGRPIEFAFL--------------------------LTFLSGIVQ 150
            .:.:||..:|:|:  ||..::....:||.|                          |:||.||:|
 Frog   131 HISVGPFPVVSLMVGSVVLSIAPDEKFAILGNATGLNKTIIDTVARDAARIAVSGTLSFLIGIIQ 195

  Fly   151 IIMGTMRMGFIFEFISMPVIKAFSSATAILVIESQLKVLLGIKYLVAGLMNSVGMLS-------- 207
            :.:|..::|||..:::.|::..|::|.|..|..||.|::|.:.     ..|..|:||
 Frog   196 LALGIFQIGFIVRYLADPLVGGFTTAAAFQVFVSQFKLVLNVP-----TQNYNGVLSIIYTIRDI 255

  Fly   208 -SRIEESNMADLIMGVCAIVFLLLLELLDRVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIVSF 271
             ..|..:|:||||.|:...|..::::.:     |::..:|.|:     ......::.::|..:|
 Frog   256 FMNIRLTNIADLIAGLLTFVVCVVVKEI-----NDRYKRIFRV-----PIPIEVIVTIVATGIS- 309

  Fly   272 IWIQKCGQVPYALSKNA------LSTLPNFTVPSFHIETAERNYSIWEVLKELNIGIIVIPIVGI 330
                      |.::.:|      ::|:|:..:|....:.:        :..::......|.||..
 Frog   310 ----------YGVNLHAKYNAGIVATIPSGFIPPMTPDVS--------LFSQIGSSAFSIGIVAY 356

  Fly   331 LTNISIGKL--TPKGL-VDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLY 392
            ...:|:||:  |.... ||.|||.:..|:.|:||.......::.|.:|.|:..:.|.||.:|.:.
 Frog   357 AVAVSVGKVYATKHNYEVDGNQEFIAFGISNLFGGAFSCFCATTALSRTAVQESTGGRTQIAGII 421

  Fly   393 LGIIVLLALSYLSPYFNYIPEATLAAILICSIFTLL--DFKLPMRLWRDSKRDFATWLLCFCVSV 455
            ...|||:|:..|......:.::.||||:|.::..:.  .|.:| |||:.:|.|.|.|:.....|:
 Frog   422 SAGIVLIAIVALGRLLEPLQKSVLAAIVIANLKGMFWQVFDIP-RLWKQNKWDSAIWVFTCIASI 485

  Fly   456 LFGVEVGLFVSIVVTALHLLFLWARPEIRVKIEQLDEMQYIRVTPSNGIYFPAINYLRERVLKAC 520
            ..|::.||...       |||..|...:||:......:..:   |...||         :.:|
 Frog   486 FLGLDSGLLAG-------LLFGLATILLRVQFPSCGALGNV---PGTDIY---------KNVK-- 529

  Fly   521 EQADFRITVVIDGQRI----SGMDYTAAQGI-----SKLSSDLCRQADASSSTLLILFRFPEHLQ 576
               :::..:..:|.:|    |||.|....|.     |.:..|..:..:..:..|       ..:|
 Frog   530 ---EYKNLIEPEGVKIIRHTSGMFYGNIDGFKNAIKSIVGFDPVKVYNKRTKAL-------RKIQ 584

  Fly   577 RLI---------------DNTDNLVFCESENKVKEFLTQESLRNGYINLKEHIRASID----LGY 622
            :||               ..|||..| |.:..|::   .|...||.:..|| :...:|    |..
 Frog   585 KLIKKGQLRSTKNGVISNTGTDNEGF-EPDEDVED---PEQENNGAVQTKE-VEIQVDWNSELPV 644

  Fly   623 KIDI 626
            ||.:
 Frog   645 KISV 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	PRK11660	50..557	CDD:481320	142/564 (25%)
slc26a4.3	NP_001107135.1	PRK11660	66..723	CDD:481320	161/654 (25%)