Protein Alignment CG5404 and SLC26A6

DIOPT Version :9

• Sequence 1: NP_650482.1
• Gene: CG5404 / 41901
• FlyBaseID: FBgn0038354
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_075062.2
• Gene: SLC26A6 / 65010
• HGNCID: 14472
• Length: 759
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 138/557 - (24%)
• Similarity: 260/557 - (46%)
• Gaps: 91/557 - (16%)

  Fly    33 GKAPRMNKWKRRLH-----------RHVPVFQWLPLYST-EWGIDDFIAGITLGLTIIPESMACA 85
            |.|||.::|:..|.           :|:||..|||.|.. :|.:.|.::|:::.:..:|:.:|.|
Human    48 GSAPRTHQWRTWLQCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYA 112

  Fly    86 LLAGLPARYGLCSAFIGPLIYMVFGSIDKVIIGPTSLVALVSVQFTV------------------ 132
            ||||||..:||.|:|....||.:||:...:.:|..::::::....|.
Human   113 LLAGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARD 177

  Fly   133 GRPIEFAFLLTFLSGIVQIIMGTMRMGFIFEFISMPVIKAFSSATAILVIESQLKVLLGIKYLVA 197
            ...::.|..|:.|.|:.|:.:|.:..||:..::|.|:::.:::|.|:.|..||||.:.|:.
Human   178 AARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLH---- 238

  Fly   198 GLMNSVGMLSS---------RIEESNMADLIMGVCAIVFLLLLELLDRVANNEKRNKILRIFCRY 253
             |.:..|.||.         ::.:|.:..::....|.|.|::::||     |:|..:.|.:
Human   239 -LSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLL-----NDKLQQQLPM---- 293

  Fly   254 LSTSRNTLIVLIAAI-VSFIWIQKCGQ-VPYALSKNALSTLPNFTVPSFHIETAERNYSIWEVLK 316
              .....|:.||.|. :|:      |. :.:....:.:..:|...||.....|        ::..
Human   294 --PIPGELLTLIGATGISY------GMGLKHRFEVDVVGNIPAGLVPPVAPNT--------QLFS 342

  Fly   317 ELNIGIIVIPIVGILTNISIGK---LTPKGLVDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAI 378
            :|......|.:||....||:||   |.....||:||||:.:||.|:.|...|..|.|.:.:|..:
Human   343 KLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLV 407

  Fly   379 STACGLRTPMANLYLGIIVLLALSYLSPYFNYIPEATLAAILICSIFTLLDFKLPMR-LWRDSKR 442
            ..:.|..:.:|.....:.:||.:..|...|:.:|:|.||||:|.::..:|.....|| ||:.::.
Human   408 QESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRA 472

  Fly   443 DFATWLLCFCVSVLFGVEVGLFVSIVVTAL---------HLLFLWARPEIRV-----KIEQLDEM 493
            |...||:.|..::|..:::||.|:::.:.|         |...|...|:..:     :..:..|:
Human   473 DLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEV 537

  Fly   494 QYIRVTPSNG-IYFPAINYLRERVLKAC-EQADFRIT 528
            :.::|..|:. :||....:..:.:.:.| ...||.|:
Human   538 RGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLIS 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	131/529 (25%)
		STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	8/33 (24%)
SLC26A6	NP_075062.2	sulP	76..738	CDD:273284	131/529 (25%)
		HCO3_cotransp	<299..451	CDD:304903	45/165 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	636..657
		STAS_SulP_like_sulfate_transporter	<656..735	CDD:132913

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810