DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5404 and si:ch211-117c9.2

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	XP_685992.2	Gene:	si:ch211-117c9.2 / 557779	ZFINID:	ZDB-GENE-110408-11	Length:	757	Species:	Danio rerio

Alignment Length:	552	Identity:	134/552 - (24%)
Similarity:	250/552 - (45%)	Gaps:	104/552 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 MNKWKRRLHRHVPVFQWLPLYS-TEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFI 101
            :.:||..:...:||..|:|.|| .|.|:.|.::|:::|:..:|:.||.||||.:|..:||.::|.
Zfish    56 VGQWKVWILAWMPVLSWIPCYSIRENGLGDLVSGVSVGIMHLPQGMAYALLASVPPVFGLYTSFY 120

  Fly   102 GPLIYMVFGSIDKVIIGPTSLVALV--SVQ---------FTVG--------------RPIEFAFL 141
            ..|:|.:||:...:.||..::::::  ||.         .|.|              :.::.|..
Zfish   121 PVLVYFIFGTSKHISIGTFAVISIMIGSVSERLAPDGHFLTNGTNGLVVVDTEARDLQRLKVAAA 185

  Fly   142 LTFLSGIVQIIMGTMRMGFIFEFISMPVIKAFSSATAILVIESQLKVLLGIK--------YLVAG 198
            .|.|.||.|:::|.:|.||:..::|.|:::.:::..|...|.:|||.:.|:.        .|:..
Zfish   186 TTLLCGIFQVLLGVVRFGFVVTYLSEPLVRGYTTGAAAHAITAQLKYMFGVSPRRFTGPLQLLYT 250

  Fly   199 LMNSVGMLSSRIEESNMADLIMGVCAIVFLLLLELLDRVANNEKRNKILRIFCRYLSTSRNTLIV 263
            |:...|:|    .::::..|::.:.::..|::::.::...::...   |.|....:..:..|||.
Zfish   251 LVELCGLL----PQTHVPTLVVSLVSLTALVIVKEINSCYSHRLP---LPIPIELMVITAGTLIS 308

  Fly   264 LIAAIVSFIWIQKCGQVPYALSKNALSTLPNFTVPSFHIETAERNYSIWEVLKELNIGIIVIPIV 328
            ....:.:...:...|::|..|..      |......|....|...::              :.:|
Zfish   309 HYTEMKTINGVDVVGEIPKGLMP------PRVPEVCFFSSVAGDAFA--------------VAVV 353

  Fly   329 GILTNISIGKL--TPKGL-VDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMAN 390
            |...:||:||:  ...|. ||:||||:.:||.|..|...|....:.:.:|..|..:.|.:|.:|.
Zfish   354 GYAISISLGKIFALKHGYKVDSNQELVALGLSNTIGGFFQCYAVTSSMSRSLIQESTGGKTQVAG 418

  Fly   391 LYLGIIVLLALSYLSPYFNYIPEATLAAILICSIFTLL----DFKLPMRLWRDSKRDFATWLLCF 451
            |...:|||:.:..|.|.|..:|.|.|:.|:..::..:.    |  || .|||.:|.|...||:.|
Zfish   419 LISAVIVLITVLKLGPLFEELPTAVLSTIVFVNLKGMFMQCRD--LP-ALWRSNKVDLLVWLVTF 480

  Fly   452 CVSVLFGVEVGLFVSIVVTALHLLFLWARP-----------EIRVKIEQLD-------------- 491
            ..:||..:::||..||..|.|.::|...||           |:.::.|...
Zfish   481 LCTVLLNLDLGLAASITFTLLTVIFRTQRPRYSLLGRVPDTELYLETESYKAAKAIPGITIFRSS 545

  Fly   492 --------EMQYIRVTPSNGIYFPAINYLRER 515
                    |:.:..:...:||..|.|..|::|
Zfish   546 TMIYYANAELYHEALLEKSGINIPKILELKKR 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	132/540 (24%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	6/18 (33%)
si:ch211-117c9.2	XP_685992.2	sulP	68..732	CDD:273284	132/540 (24%)
si:ch211-117c9.2	XP_685992.2	STAS_SulP_like_sulfate_transporter	<660..729	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910