DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5404 and slc26a2

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	XP_005173217.1	Gene:	slc26a2 / 557046	ZFINID:	ZDB-GENE-030717-3	Length:	699	Species:	Danio rerio

Alignment Length:	676	Identity:	152/676 - (22%)
Similarity:	287/676 - (42%)	Gaps:	128/676 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EKATARALLPGAISKPASEAGKAPRMNKWKRRLHRHVPVFQWLPLYS-TEWGIDDFIAGITLGLT 76
            ||.:.:..|...:.|.:....:.      |.::.:..|:.:|||.|. .:|.|.|.::|:.:|:.
Zfish    32 EKVSWKEALRKKVKKCSCSTARV------KSQIMKSFPIVKWLPRYRFKDWIIGDAMSGLIVGIL 90

  Fly    77 IIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSIDKVIIGPTSLVALVSVQFTVGRPIE---- 137
            ::|:|:|.:||||....|||.::|...:||.:.|:...:.:|...::.|:     ||:.::
Zfish    91 LVPQSIAYSLLAGQDPIYGLYTSFFANIIYALLGTSRHISVGMFGVLCLL-----VGQVVDRELT 150

  Fly   138 ----------------------------FAFL----LTFLSGIVQIIMGTMRMGFIFEFISMPVI 170
                                        :|.:    |||.:||.|::||.:::||:..|:|..::
Zfish   151 LAGYSSDINQTTLGNVDNSTGPICDRSCYAIMVGATLTFTAGIYQVLMGLLQIGFVSVFLSDSLL 215

  Fly   171 KAFSSATAILVIESQLKVLLGIKY-LVAG---LMNSVGMLSSRIEESNMADLIMG-VCAIVFLLL 230
            ..|::..::.::.||:|..||:.. .|.|   |:.:...|...:..:|:.|||.. :|.:|.:..
Zfish   216 SGFATGASLTILTSQIKYFLGLHLPRVQGWGSLIKTWISLFKNLGHTNLCDLITSLICLLVLVPA 280

  Fly   231 LELLDRVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIVSFIWIQKCGQVPYALSKNALSTLP-N 294
            .||.||.....|......:|           :|:.|.:.|..     |........:...|:| .
Zfish   281 KELNDRFKAKLKAPIPFELF-----------VVIAATLASHF-----GHFKDTYGSDVAGTIPTG 329

  Fly   295 FTVPSFHIETAERNYSIWEVLKELNIGIIVIPIVGILTNISIGKLTPKG---LVDTNQELLTVGL 356
            |..|.      ..|.|:   :..:.|..:.|.|||....:|:.::..|.   :|:.||||..:|.
Zfish   330 FMAPQ------SPNLSL---VPNIAIDALSIAIVGFAITVSLSEMFAKKHGYIVNANQELNAIGN 385

  Fly   357 CNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLALSYLSPYFNYIPEATLAAILI 421
            ||:..|.......|.|.|:..:..:.|..|.::.|...:::||.:..::|.|..:.:..||.|::
Zfish   386 CNIISSYFHCFTVSAALTKTLVKESTGCHTQISGLVTALVLLLVMLVIAPAFYSLQKCVLAVIIV 450

  Fly   422 CSI-FTLLDFKLPMRLWRDSKRDFATWLLCFCVSVLFGVEVGLFVSIVVTALHLLFLWARPEI-- 483
            .:: ..|..|....::||.::.|...|||....|.|...|:||.|.:||:|..:|   .|.:.
Zfish   451 VNLRGALRKFGDIPQMWRVNRVDTVIWLLTMATSALVNTELGLLVGVVVSAFCVL---GRTQFAQ 512

  Fly   484 ---------RVKIEQLDEMQYIRVTPSNGI--YFPAINYLRERVLKACEQADFRITVVIDGQRIS 537
                     |...|.:.....::..|...:  |...|.|..:.:.|.....:..:..:.:..:..
Zfish   513 ALQLGQAGDRELFEDIASYNGLQTQPDVAVFRYEAPIYYANQSLFKKSLYRNVGLDPLKEKAKQR 577

  Fly   538 GMDYTAAQGISKLSSDLCRQADASSSTLLILFRFPEH--LQRLIDNTDNLVFCESE--NKVKE-- 596
            .::....|..|:  .|..::.|||::..|:     :|  ...|:.:..:::|.::.  |.:||
Zfish   578 KLEKQRKQKHSR--EDQKQEMDASTNVNLL-----QHSSFHTLVIDCSSVLFLDTAGVNALKEVF 635

  Fly   597 ----------FLTQ------ESLRNG 606
                      .|.|      :|||.|
Zfish   636 KDYKELGVNVLLAQCNTSVIDSLRRG 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	131/566 (23%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	7/57 (12%)
slc26a2	XP_005173217.1	sulP	63..681	CDD:273284	147/639 (23%)
slc26a2	XP_005173217.1	STAS_SulP_like_sulfate_transporter	531..665	CDD:132913	24/138 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810