Protein Alignment CG5404 and SLC26A4

DIOPT Version :9

• Sequence 1: NP_650482.1
• Gene: CG5404 / 41901
• FlyBaseID: FBgn0038354
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_000432.1
• Gene: SLC26A4 / 5172
• HGNCID: 8818
• Length: 780
• Species: Homo sapiens
• Alignment Length: 578
• Identity: 149/578 - (25%)
• Similarity: 252/578 - (43%)
• Gaps: 131/578 - (22%)

  Fly    49 VPVFQWLPLYST-EWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSI 112
            ||:.:|||.|.. ||.:.|.|:|::.||....:.||.||||.:|..|||.|||...|.|.:||:.
Human    69 VPILEWLPKYRVKEWLLSDVISGVSTGLVATLQGMAYALLAAVPVGYGLYSAFFPILTYFIFGTS 133

  Fly   113 DKVIIGPTSLVALV--SVQFTVGRPIEF---------------------------AFLLTFLSGI 148
            ..:.:||..:|:|:  ||..::.....|                           |..||.|.||
Human   134 RHISVGPFPVVSLMVGSVVLSMAPDEHFLVSSSNGTVLNTTMIDTAARDTARVLIASALTLLVGI 198

  Fly   149 VQIIMGTMRMGFIFEFISMPVIKAFSSATAILVIESQLKVLLGIKYLVAGLMNSVGMLS------ 207
            :|:|.|.:::|||..:::.|::..|::|.|..|:.||||::|.:     ...|..|:||
Human   199 IQLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNV-----STKNYNGVLSIIYTLV 258

  Fly   208 ---SRIEESNMADLIMGVCAIVFLLLLELLDRVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIV 269
               ..|.::|:||...|:..||..:.::.|    |:..|:||      .:......::.:||..:
Human   259 EIFQNIGDTNLADFTAGLLTIVVCMAVKEL----NDRFRHKI------PVPIPIEVIVTIIATAI 313

  Fly   270 SFIWIQKCGQVPYALSKN----ALSTLPNFTVP------SFHIETAERNYSIWEVLKELNIGIIV 324
            |:         ...|.||    .:.::|...:|      |...|....::|
Human   314 SY---------GANLEKNYNAGIVKSIPRGFLPPELPPVSLFSEMLAASFS-------------- 355

  Fly   325 IPIVGILTNISIGKLTPKG---LVDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRT 386
            |.:|.....:|:||:....   .:|.|||.:..|:.|:|........::.|.:|.|:..:.|.:|
Human   356 IAVVAYAIAVSVGKVYATKYDYTIDGNQEFIAFGISNIFSGFFSCFVATTALSRTAVQESTGGKT 420

  Fly   387 PMANLYLGIIVLLALSYLSPYFNYIPEATLAAILICSI----FTLLDFKLPMRLWRDSKRDFATW 447
            .:|.:....||::|:..|......:.::.|||::|.::    ..|.|  :| ||||.:|.|...|
Human   421 QVAGIISAAIVMIAILALGKLLEPLQKSVLAAVVIANLKGMFMQLCD--IP-RLWRQNKIDAVIW 482

  Fly   448 LLCFCVSVLFGVEVGLFVSIVVTALHLLFLWARPEIRVKIEQLDEMQYIRVTPSNGIYFPAINY- 511
            :....||::.|:::||...::...|.::       :||:....:.:..|   ||..||....||
Human   483 VFTCIVSIILGLDLGLLAGLIFGLLTVV-------LRVQFPSWNGLGSI---PSTDIYKSTKNYK 537

  Fly   512 -LRE----RVL--------------KACEQADFRITVVIDGQRISGMDYTAAQGISKL 550
             :.|    ::|              |.|    .:.||..|..|:......|.:.|.||
Human   538 NIEEPQGVKILRFSSPIFYGNVDGFKKC----IKSTVGFDAIRVYNKRLKALRKIQKL 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	148/577 (26%)
		STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	18/73 (25%)
SLC26A4	NP_000432.1	sulP	70..725	CDD:273284	148/577 (26%)
		STAS_SulP_like_sulfate_transporter	536..722	CDD:132913	13/60 (22%)
		Snf7	<583..654	CDD:304451	4/9 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3293
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.860