DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5404 and Slc26a11

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	XP_038943458.1	Gene:	Slc26a11 / 360670	RGDID:	1306178	Length:	593	Species:	Rattus norvegicus

Alignment Length:	520	Identity:	185/520 - (35%)
Similarity:	303/520 - (58%)	Gaps:	22/520 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LHRHVPVFQWLPLYSTEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVF 109
            |.|.:||..|||.||..|...|.|||:::|||:||:::|.|.:||||.:|||.|||:|..:|.|.
  Rat    13 LRRRLPVLAWLPNYSLRWLRMDVIAGLSVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFVL 77

  Fly   110 GSIDKVIIGPTSLVALVSVQFTVGRPIEFAFLLTFLSGIVQIIMGTMRMGFIFEFISMPVIKAFS 174
            |:...|.:|||::::|:...:|...| .:|.||.||||.:|:.||.:.:||:.:|||.||||.|:
  Rat    78 GTSRDVTLGPTAIMSLLVSYYTFREP-AYAVLLAFLSGCIQLAMGLLHLGFLLDFISCPVIKGFT 141

  Fly   175 SATAILVIESQLKVLLGIKYLVAGLMNSVGMLSSRIEESNMADLIMGVCAIVFLLLLELL-DRVA 238
            ||.:|.:...|:|.|||::.:.......|......|.|:.:.|.|:|:..:|.||:|:|: :.:.
  Rat   142 SAASITIGFGQVKNLLGLQNIPRQFFLQVYHTFLHIGETRVGDAILGLVCMVLLLVLKLMREHIP 206

  Fly   239 NNEKRNKILRIFCRYL----STSRNTLIVLIAAIVSFIWIQKCGQVPYALSKNALSTLPNFTVPS 299
            .......:...|.|.|    :|:||.|:|..||::::.: :..|..|:.|:......||...:|.
  Rat   207 PPHPEMPLGVKFSRGLVWTVTTARNALVVSFAALIAYAF-EVTGSHPFILTGKIAQGLPPVRMPP 270

  Fly   300 FHIETAERNYSIWEVLKELNIGIIVIPIVGILTNISIGKLTPKG---LVDTNQELLTVGLCNMFG 361
            |.:.|..:..|..|:::::.:|:.|:|::|:|..|::.|.....   .:|.|||||.:||.|:.|
  Rat   271 FSVTTDNKTISFSEMVQDMGVGLAVVPLMGLLETIAVAKSFASQNNYRIDANQELLAIGLTNVLG 335

  Fly   362 SCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLALSYLSPYFNYIPEATLAAILICSIFT 426
            |.|.:.|.:|:|.|.|::...|:.||...|..|::|||:|.||:..|.|||::.|||::|.::..
  Rat   336 SLVSSYPVTGSFGRTAVNAQTGVCTPAGGLVTGVLVLLSLDYLTLLFYYIPKSALAAVIIMAVAP 400

  Fly   427 LLDFKLPMRLWRDSKRDFATWLLCFCVSVLFG---VEVGLFVSIVVTALHLLFLWARPEIRVKIE 488
            |.|.|:..|||...:.|    ||..||:.|..   ::.|:....:|:.|.||...|||:     .
  Rat   401 LFDVKIFRRLWLVQRLD----LLPLCVTFLLSFWEIQYGILAGTLVSLLILLHSVARPK-----T 456

  Fly   489 QLDEMQYIRVTPSNGIYFPAINYLRERVLKACEQADFRITVVIDGQRISGMDYTAAQGISKLSSD 553
            |:.|.|.:.:.|::|::|||::.|||.:.|...:|....:.|::...:|.:|||...|:.:|..|
  Rat   457 QVSEGQILVLQPASGLHFPAVDALREAMTKRALEASPPRSAVLECTHVSNIDYTVILGLGELLED 521

Fly 554 553
Rat 522 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	183/515 (36%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	18/56 (32%)
Slc26a11	XP_038943458.1	sulP	18..542	CDD:273284	183/515 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335188
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.960