DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5404 and slc26a11

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_956061.1	Gene:	slc26a11 / 327138	ZFINID:	ZDB-GENE-030131-5349	Length:	572	Species:	Danio rerio

Alignment Length:	554	Identity:	185/554 - (33%)
Similarity:	310/554 - (55%)	Gaps:	33/554 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 WKRRLHRHVPVFQWLPLYSTEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLI 105
            |...|....|:..|||.|:..|...|.|||:|:|||.:|:::|.|.:||||.:|||.|||:|..|
Zfish     7 WFPALRSCFPIITWLPRYNLTWLKMDVIAGLTVGLTAVPQALAYAEVAGLPVQYGLYSAFMGGFI 71

  Fly   106 YMVFGSIDKVIIGPTSLVALVSVQFTVGRPIEFAFLLTFLSGIVQIIMGTMRMGFIFEFISMPVI 170
            |.:||:...:.:|||::::|:...:..|.|: ||.:||.|.|::|..|..:|:||:.:|||.|||
Zfish    72 YCIFGTSKDITLGPTAIMSLLCSSYITGDPV-FAVVLTLLCGVIQTGMALLRLGFLLDFISYPVI 135

  Fly   171 KAFSSATAILVIESQLKVLLGIKYLVAGLMNSVGMLSSRIEESNMADLIMGVCAIVFLLLLELLD 235
            |.|:.|.|:.:...|:|.:||:|.:.......|.....:|.|:.:.|:|:|:..:.|||:|..:.
Zfish   136 KGFTCAAAVTIGFGQVKNILGLKEIPQQFFLQVYYTFHKIPEARVGDVILGLSCLFFLLILTFMK 200

  Fly   236 RVANNEKRN-----KILRIFCRYLSTSRNTLIVLIAAIVSFIWIQKCGQVPYALSKNALSTLPNF 295
            ...|:.:..     :..|.....|:|.||.|:|:.||.|:|. .:..|...::|:......||.|
Zfish   201 NSLNSAEDEASFLVRSARQLLWSLATIRNALVVIAAAGVAFS-AEVTGNHFFSLTGKTAKGLPPF 264

  Fly   296 TVPSFHIETAERNYSIW--EVLKELNIGIIVIPIVGILTNISIGKL---TPKGLVDTNQELLTVG 355
            ..|... ||......|.  ::.|:|..|:.|||::|:|.:|:|.|.   .....:|.||||..:|
Zfish   265 RAPPLS-ETIANGTVITFSDIAKDLGGGLAVIPLMGVLESIAIAKAFGSKNNYRIDANQELFAIG 328

  Fly   356 LCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLALSYLSPYFNYIPEATLAAIL 420
            |.|:.||.|.|.|.:|:|.|.|:::..|:.:|...:...:||||:|::|.|.|.|||:|:|||::
Zfish   329 LTNIMGSFVSAYPVTGSFGRTAVNSQTGVCSPAGGIITSVIVLLSLAFLMPLFFYIPKASLAAVI 393

  Fly   421 ICSIFTLLDFKLPMRLWRDSKRDFATWLLCFCVSVLFGVEVGLFVSIVVTALHLLFLWARPEIRV 485
            ||::..::||::|:.:||..:.|...:|:.|.:| .:.|:.|:...::|:|..||::.|||:::|
Zfish   394 ICAVSPMVDFRVPLHIWRVKRLDLLPFLVTFLLS-FWEVQYGIAGGVLVSAFMLLYIMARPKVKV 457

  Fly   486 K-----IEQLDEMQYIRVTPSNGIYFPAINYLRERVLKACEQADFRITVVIDGQRISGMDYTAAQ 545
            .     :.::|          ||:.|.:..:|...|.|....|....::|:|..:||.:|:|...
Zfish   458 SDHGVIVLEID----------NGLNFTSTEHLSRLVYKHALHASPPRSLVLDCSQISSIDFTVIH 512

  Fly   546 GISKLSSDLCRQADASSSTLLILFRFPEHLQRLI 579
            .:    :||.:|.....:.|:.....|..||.|:
Zfish   513 EL----TDLLKQFQIRGAALIFTGLKPSVLQVLL 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	177/521 (34%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	13/55 (24%)
slc26a11	NP_956061.1	sulP	16..541	CDD:273284	182/542 (34%)
slc26a11	NP_956061.1	STAS_SulP_like_sulfate_transporter	454..546	CDD:132913	23/103 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574460
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.810