Protein Alignment CG5404 and Slc26a8

DIOPT Version :10

• Sequence 1: NP_650482.1
• Gene: CG5404 / 41901
• FlyBaseID: FBgn0038354
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: XP_063135199.1
• Gene: Slc26a8 / 309646
• RGDID: 1308898
• Length: 1017
• Species: Rattus norvegicus
• Alignment Length: 702
• Identity: 158/702 - (22%)
• Similarity: 279/702 - (39%)
• Gaps: 185/702 - (26%)

  Fly     5 LETEAEALEKATARALLPGAISKPASEAGKAPRMNKWKRRLHRHVPVFQWLPLYSTEWGIDDFIA 69
            :.:||..:.:.::|           |..|:||.:..|.          ...|..||...     |
  Rat    80 MSSEAYTMRRISSR-----------STGGRAPLLGTWT----------STSPPSSTTSS-----A 118

  Fly    70 GITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSIDKVIIGPTSLVALVSVQFTVGR 134
            |:||.|      :...|:..|...|   :||...:||::|||..::.|||..||:.:.:.....|
  Rat   119 GLTLSL------LTRQLIPPLNVAY---AAFCSSVIYVIFGSCHQMSIGPFFLVSALMINVLKER 174

  Fly   135 PIEFAFLL----------------------------TFLSGIVQIIMGTMRMGFIFEFISMPVIK 171
            |.....|:                            |||:||:|:.||.:.|||:..::......
  Rat   175 PFNNGHLIMGTFVKDDFSVPTFYLNYNRSLSMVASTTFLTGIIQLSMGMLGMGFVATYLPEAATS 239

  Fly   172 AFSSATAILVIESQLKVLLGIKYL-----VAGLMNSVGMLSSRIEESNMADLIMGVCAIVFLLLL 231
            |:.:|.|:.:|.:|:..:.||...     :|.:.|.:....: :.::|...:::.:.|:|.|
  Rat   240 AYLAAVALHIILAQMTCIFGIMVSFHAGPIAFIYNIINYCIA-LPKANSTSILLFLTAVVAL--- 300

  Fly   232 ELLDRVANNEKRNKILRI-FCRY-LSTSRNTLIVLIAAIVSFIWIQKCGQVPYAL--SKNALSTL 292
                ||      ||.:|| |.|| :......|::|..::::       .::..|.  ||..::.:
  Rat   301 ----RV------NKCIRISFNRYPIEFPMELLLILGFSMLT-------SRITMATENSKMLINMI 348

  Fly   293 P-NFTVPSFHIETAERNYSIWEVLKELNIGIIVIPIVGILTNISIGKLTP---KGLVDTNQELLT 353
            | :|..|    ||.|     :.:|..:.:..:.:.:|.....||:||...   ....::||:|:.
  Rat   349 PYSFVFP----ETPE-----FGILSRIVLQALSLSVVSSFLLISLGKKIANLHNYRTNSNQDLIA 404

  Fly   354 VGLCNMFGSCVQAMPSSGAFTRYAI--------------------------STAC-------GLR 385
            :||||:..|..:....:|...|..|                          :.||       .|.
  Rat   405 IGLCNLVSSFFRCCVFTGGMARTIIQDKSGGRQQKKLACFSANRRPQLQTGTNACLTRSLQPALS 469

  Fly   386 TPMANLYLGIIVLLALSYLSPYFNYIPEATLAAILICSIFTLLD--FKLPMRLWRDSKRDFATWL 448
            ...|:|....::||.:..:..:|:.:|.|.||.|::.::...|:  :.|| .|||..:.:...|:
  Rat   470 PQFASLVGAGVMLLLMVKIGSFFDNLPNAVLAGIILSNVVPYLETIYNLP-TLWRQDQYECVVWM 533

  Fly   449 LCFCVSVLFGVEVGLFVSIVVTALHLLFLWARPEIRVKIEQLDEMQYIRVTPSNGIYFPAINYLR 513
            :.|..::..|::|||.:|:|.|    .|:......|.||..|.::      |:..|| ..:|..|
  Rat   534 VTFSAAIFLGLDVGLLISLVFT----FFVITVRSHRTKILVLGQI------PNTNIY-RNVNEYR 587

  Fly   514 E-------RVLKACEQADFRITVVIDGQRISGMDYTAAQGISKLSSDLCRQADASSSTLL---IL 568
            |       ::|:.|..    ||.|               .:..|...|.::.:.....|.   |.
  Rat   588 EVILIPGVKILQCCSS----ITFV---------------NVYHLKHKLLKEVNMVKLPLKEEEIY 633

  Fly   569 FRFPEHLQRLIDNTDNLVFCESENKVKEFLTQESLRNGYINLKEHIRASIDL 620
            ..|.|....:.:|.....||:.|....|.....:.|  |.|.:|| .:||:|
  Rat   634 ALFHESETSIAENKLCRCFCDCEELEPESRVVYTER--YENKQEH-GSSINL 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	PRK11660	50..557	CDD:481320	133/589 (23%)
Slc26a8	XP_063135199.1	None