DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5404 and Slc26a9

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_001100642.1	Gene:	Slc26a9 / 304784	RGDID:	1310441	Length:	790	Species:	Rattus norvegicus

Alignment Length:	593	Identity:	139/593 - (23%)
Similarity:	261/593 - (44%)	Gaps:	117/593 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VPVFQWLPLYS-TEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSI 112
            :||..|||.|. .::.|.|.:.|::.|...:|:.||.||||.|||..||.|:|...|.|...|.|
  Rat    56 LPVLSWLPKYKIKDYIIPDLLGGLSGGCIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGI 120

  Fly   113 DKVIIGPTSLVAL----VSVQF-------------------TVGRPIE---FAFLLTFLSGIVQI 151
            .:::.|..:::::    :.:|.                   ||....|   .:..|..|:.::|:
  Rat   121 HQMVPGTFAVISILVGNICLQLAPESKFQIFNATTNETYVDTVAMEAERLHVSATLACLTAVIQM 185

  Fly   152 IMGTMRMGFIFEFISMPVIKAFSSATAILVIESQLKVLLGI---KYLVAG-LMNSVGMLSSRIEE 212
            .:|.|:.||:..::|...|:.|.:|..:.::.|.||.:.|:   .|...| ::.:...:...:..
  Rat   186 ALGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPH 250

  Fly   213 SNMADLIMGVCAIVFLLLLELLDRVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIVS------- 270
            :|:|.|:..:.:.|||:|::.|    |....:||      :.......::|::|..:|
  Rat   251 TNIASLVFALVSGVFLVLVKEL----NARYMHKI------HFPIPTEMIVVVVATAISGSCKMPK 305

  Fly   271 FIWIQKCGQVPYALSKNALSTLPNFTVPSFHIETAERNYSIWEVLKELNIGIIVIPIVGILTNIS 335
            ...:|..|::.:           .|.:|      .....|.|   |::......:.|||.:.|::
  Rat   306 KYHMQIVGEIRH-----------GFPIP------VAPMVSQW---KDMVGTAFSLAIVGYVINLA 350

  Fly   336 IGK-LTPK-GL-VDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIV 397
            :|: |..| |. ||:|||::.:|..|.|||..:......|.:........|.::.:|:|.:.::|
  Rat   351 MGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVV 415

  Fly   398 LLALSYLSPYFNYIPEATLAAILIC----SIFTLLDFKLPMRLWRDSKRDFATWLLCFC----VS 454
            ::.:..|..|...:|:|.|.|::..    |:..|.|   |..|||.||.|...|::.|.    :|
  Rat   416 MITMLVLGSYLYPLPKAVLGALIAVNLKNSLKQLTD---PYYLWRKSKLDCCVWVVSFLSSFFLS 477

  Fly   455 VLFGVEVGLFVSIVVTALHLLF-------------LWARPEIRVKIEQLDEMQYIRVTPSNGIYF 506
            :.:||.||:..||:|......|             ::..|:...::::::.::.  ||..:.:||
  Rat   478 LPYGVAVGVAFSILVVIFQTQFRNGSTLAQVMDTDIYVNPKTYNRVQEIEGVKI--VTYCSPLYF 540

  Fly   507 PAINYLRERVL---------------KACEQADFRITVVIDGQRISGMDYTAAQGISKLSSDLCR 556
            ......|::|:               |...:.:.|:.|... ||.|....|....:.:|..|.
  Rat   541 ANSEIFRQKVIAKTGMDPQKVLLAKQKYLRKQEKRMAVPTQ-QRKSLFMKTKTVSLQELQQDF-- 602

  Fly   557 QADASSST 564
              ::::||
  Rat   603 --ESAAST 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	137/583 (23%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	14/70 (20%)
Slc26a9	NP_001100642.1	sulP	57..733	CDD:273284	139/592 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900