DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5404 and Slc26a10

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	XP_006513627.1	Gene:	Slc26a10 / 216441	MGIID:	2143920	Length:	693	Species:	Mus musculus

Alignment Length:	521	Identity:	139/521 - (26%)
Similarity:	234/521 - (44%)	Gaps:	96/521 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EALEKATARALLPGAISKPASEAGKA-PRMNKWKRR-------------LHRHVPVFQWLPLYS- 59
            |.|..|..:.|..||..:|...|... |.:.:.:||             |...:|..:|||.|.
Mouse    37 EPLTHARFQELFGGAEPEPELPAEPCLPCLCRLRRRRASACSGPGAWRVLLARLPPLRWLPQYRW 101

  Fly    60 TEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSIDKVIIGPTSLVA 124
            ..|.:.|.:||:|:|:..:|:.||.|||..:|..:||.::|...|||.:.|:...:..|..::::
Mouse   102 RAWLLGDAVAGVTVGVVHVPQGMAFALLTSVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAVLS 166

  Fly   125 LVS---VQFTVGRP-----------------IEFAFLLTFLSGIVQIIMGTMRMGFIFEFISMPV 169
            |::   |:..|..|                 :..|..:.|.||.:.:.|..:::|.:..|:|.||
Mouse   167 LMTGSVVERVVPEPLAGNLSGIEREQLEARRVGAAAAVAFGSGALMLGMFVLQLGVLSTFLSEPV 231

  Fly   170 IKAFSSATAILVIESQLKVLLGIKYLVAGLMNSVGMLS---------SRIEESNMADLIMGVCAI 225
            |||.:|..|:.|:.|||..|||:     .|...:|..|         |.:.:|:.|::.:...::
Mouse   232 IKALTSGAALHVLVSQLPSLLGL-----SLPRQIGCFSLFKTLAAVLSALSQSSPAEVTISALSL 291

  Fly   226 VFLLLLELLDRVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIVSFIW-------IQKCGQVPYA 283
            |.|:.::.|    |...|:::|      .......::||:|.::.|..       :|..|.:|..
Mouse   292 VLLVPVKEL----NVRFRDRLL------TPIPGEVVMVLLATVLCFTSSLDTRYNVQVVGPLPGG 346

  Fly   284 LSKNALST---LPNFTVPSFHIETAERNYSIWEVLKELNIGIIVIPIVGILTNISIGKLTPKGLV 345
            ..:..|.|   ||.....|                  |.|.::...:...|.:|...|.:  ..:
Mouse   347 FPQPLLPTLDELPRILADS------------------LPISLVTFAVSTSLASIYADKYS--YTI 391

  Fly   346 DTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLALSYLSPYFNY 410
            :.|||||..|:.|:..|.....|:|......::....|..|.:|.|:...:||.||.:|.|:|.|
Mouse   392 EPNQELLAHGVSNLISSLFSCFPNSATLATTSLLVDAGGNTQLAGLFSCAVVLAALLWLRPFFYY 456

  Fly   411 IPEATLAAILICSI----FTLLDFKLPMRLWRDSKRDFATWLLCFCVSVLFGVEVGLFVSIVVTA 471
            :|:|.||.|.|.|:    |.:.:  || :||..|..|||.|::.:...|...|::||.|.:||:.
Mouse   457 LPKAVLACINISSMRQMFFQMQE--LP-QLWHISHVDFAVWIVTWVAVVTLNVDLGLAVGVVVSM 518

  Fly   472 L 472
            :
Mouse   519 M 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	127/467 (27%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913
Slc26a10	XP_006513627.1	sulP	91..670	CDD:273284	127/467 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000