Protein Alignment CG5404 and SLC26A2

DIOPT Version :10

• Sequence 1: NP_650482.1
• Gene: CG5404 / 41901
• FlyBaseID: FBgn0038354
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_000103.2
• Gene: SLC26A2 / 1836
• HGNCID: 10994
• Length: 739
• Species: Homo sapiens
• Alignment Length: 663
• Identity: 145/663 - (21%)
• Similarity: 275/663 - (41%)
• Gaps: 150/663 - (22%)

  Fly    40 KWKRRLHRHVPVFQWLPLYSTEWGI-DDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGP 103
            |.|..:...:||.||||.|..:..| .|.::|:.:|:.::|:|:|.:||||....|||.::|...
Human    84 KAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFAS 148

  Fly   104 LIYMVFGSIDKVIIGPTSLVALVSVQFTVGRPIE------------------------------- 137
            :||.:.|:...:.:|...::.|: :..||.|.::
Human   149 IIYFLLGTSRHISVGIFGVLCLM-IGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRIC 212

  Fly   138 ----FAFL----LTFLSGIVQIIMGTMRMGFIFEFISMPVIKAFSSATAILVIESQLKVLLGIKY 194
                :|.:    :||::|:.|:.||..::||:..::|..::..|.:..:..::.||.|.|||:.
Human   213 DKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLN- 276

  Fly   195 LVAGLMNSVGMLSS-------RIEESNMADLIMG-VCAIVFLLLLELLDRVANNEKRNKI---LR 248
              ....|.||.|.:       .|.::|:.|||.. :|.:|.|...||     |...::|:   :.
Human   277 --LPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPTKEL-----NEHFKSKLKAPIP 334

  Fly   249 IFCRYLSTSRNTLIVLIAAIVSFIWIQKCGQVPYALSKNALSTLPNFTVPSFHIETAERNYSI-- 311
            |          .|:|::||.::    ...|:    |.:|..|::..      ||.|......:
Human   335 I----------ELVVVVAATLA----SHFGK----LHENYNSSIAG------HIPTGFMPPKVPE 375

  Fly   312 WEVLKELNIGIIVIPIVGILTNISIGKLTPKG---LVDTNQELLTVGLCNMFGSCVQAMPSSGAF 373
            |.::..:.:..|.|.|:|....:|:.::..|.   .|..|||:..:|.||:..|......:|.|.
Human   376 WNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAAL 440

  Fly   374 TRYAISTACGLRTPMANLYLGIIVLLALSYLSPYFNYIPEATLAAILICSI-FTLLDFKLPMRLW 437
            .:..:..:.|..|.::.:...:::||.|..::|.|..:.::.|..|.|.:: ..|..|:...::|
Human   441 AKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMW 505

  Fly   438 RDSKRDFATWLLCFCVSVLFGVEVGLFVSIVVTALHLLFLWARP--------EIRVKIEQLDEMQ 494
            ..|:.|...|.:....|.|...|:||.|.:..:...::....:|        |.....|.:...:
Human   506 SISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYK 570

  Fly   495 YIRVTP-------------------SNGIYFPAINYLRERVL--KACE-------------QADF 525
            .:::.|                   .:.:|...:|.:..:|.  ||.:             |.:.
Human   571 NLQIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEM 635

  Fly   526 RI----------TVVIDGQRISGMDYTAAQGISKLSSDLCRQADASSSTLLILFRFPEHLQRLID 580
            .:          |:|||...|..:| ||  ||..| .::.|..:|....:|:....|    .:.|
Human   636 SVQLSHDPLELHTIVIDCSAIQFLD-TA--GIHTL-KEVRRDYEAIGIQVLLAQCNP----TVRD 692

  Fly   581 NTDNLVFCESENK 593
            :..|..:|:.|.:
Human   693 SLTNGEYCKKEEE 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	PRK11660	50..557	CDD:481320	135/615 (22%)
SLC26A2	NP_000103.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27
		sulP	94..715	CDD:273284	143/653 (22%)