Protein Alignment CG5404 and Slc26a6

DIOPT Version :10

• Sequence 1: NP_650482.1
• Gene: CG5404 / 41901
• FlyBaseID: FBgn0038354
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_001395316.1
• Gene: Slc26a6 / 171429
• MGIID: 2159728
• Length: 758
• Species: Mus musculus
• Alignment Length: 554
• Identity: 147/554 - (26%)
• Similarity: 256/554 - (46%)
• Gaps: 92/554 - (16%)

  Fly     6 ETEAEALEKATARALLPGAISKPASEAGKAPRMNKW-------KRRLH----RHVPVFQWLPLYS 59
            |.|.:..:....|.||.....:.....|.|.:.::|       :.|.|    :||||..|||.|.
Mouse    23 EMELQRRDYHVERPLLNQEQLEDLGHWGPAAKTHQWRTWFRCSRARAHSLLLQHVPVLGWLPRYP 87

  Fly    60 T-EWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSIDKVIIGP---- 119
            . ||.:.|.::|:::.:..:|:.:|.|||||||..:||.|:|....||.:||:...:.:|.
Mouse    88 VREWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPMFGLYSSFYPVFIYFLFGTSRHISVGTFAVM 152

  Fly   120 TSLVALVSVQFTVGRP-------------IEFAFLLTFLSGIVQIIMGTMRMGFIFEFISMPVIK 171
            :.:|..|:...|..:.             ::.|:.|:||.|:.|:.:|.:..||:..::|.|:::
Mouse   153 SVMVGSVTESLTADKAFVQGLNATADDARVQVAYTLSFLVGLFQVGLGLVHFGFVVTYLSEPLVR 217

  Fly   172 AFSSATAILVIESQLKVLLGIKYLVAGLMNSVGMLS---------SRIEESNMADLIMGVCAIVF 227
            ::::|.::.|:.||||.:.|||     |.:..|.||         :::.|:....::..:.|.|.
Mouse   218 SYTTAASVQVLVSQLKYVFGIK-----LSSHSGPLSVIYTVLEVCAQLPETVPGTVVTAIVAGVA 277

  Fly   228 LLLLELLDRVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIVSFIWIQKCGQVPYALSKN---AL 289
            |:|::||     |||.::.|.:      .....|:.||.|.          .:.|.:..|   .:
Mouse   278 LVLVKLL-----NEKLHRRLPL------PIPGELLTLIGAT----------GISYGVKLNDRFKV 321

  Fly   290 STLPNFT---VPSFHIETAERNYSIWEVLKELNIGIIVIPIVGILTNISIGK---LTPKGLVDTN 348
            ..:.|.|   :|....:|        |:...|......|.:||....||:||   |.....||:|
Mouse   322 DVVGNITTGLIPPVAPKT--------ELFATLVGNAFAIAVVGFAIAISLGKIFALRHGYRVDSN 378

  Fly   349 QELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLALSYLSPYFNYIPE 413
            |||:.:||.|:.|...|..|.|.:.:|..:..:.|..|.:|.....:.:||.:..|...|..:|:
Mouse   379 QELVALGLSNLIGGFFQCFPVSCSMSRSLVQESTGGNTQVAGAVSSLFILLIIVKLGELFRDLPK 443

  Fly   414 ATLAAILICSIFTLL-DFKLPMRLWRDSKRDFATWLLCFCVSVLFGVEVGLFVSIVVTALHLLFL 477
            |.|||::|.::..:: .|.....||:.::.|...||:.|..::|..:::||.||||.:.|.::
Mouse   444 AVLAAVIIVNLKGMMKQFSDICSLWKANRVDLLIWLVTFVATILLNLDIGLAVSIVFSLLLVV-- 506

  Fly   478 WARPEIRVKIEQLDEMQYIRVTPSNGIYFPAINY 511
                 :|:   ||.....:...|...||.....|
Mouse   507 -----VRM---QLPHYSVLGQVPDTDIYRDVAEY 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	PRK11660	50..557	CDD:481320	135/499 (27%)
Slc26a6	NP_001395316.1	PRK11660	78..737	CDD:481320	135/499 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	585..608