Protein Alignment CG5404 and SLC26A7

DIOPT Version :10

• Sequence 1: NP_650482.1
• Gene: CG5404 / 41901
• FlyBaseID: FBgn0038354
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_599028.1
• Gene: SLC26A7 / 115111
• HGNCID: 14467
• Length: 663
• Species: Homo sapiens
• Alignment Length: 558
• Identity: 128/558 - (22%)
• Similarity: 236/558 - (42%)
• Gaps: 123/558 - (22%)

  Fly    40 KWKRRLHRHVPVFQWLPLYSTEWG-IDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGP 103
            :|.|   |.:|:..|.|.|:.:.. :.|.::||.|.:..:.:.:|.|:|:.:...:||..:....
Human    26 QWCR---RRLPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPA 87

  Fly   104 LIYMVFGSIDKVIIGPTSLVALVSV--------------------------QFTVGRPIEFAFLL 142
            :||.:||....|..|..:|.:|:|.                          .|.:.| |..|..:
Human    88 IIYAIFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEMQR-IHVAAAV 151

  Fly   143 TFLSGIVQIIMGTMRMGFIFEFISMPVIKAFSSATAILVIESQLKVLLGIK-----------YLV 196
            :||.|::|:.|..:::|.....::.|||.|.::..|..|:.||:|.|||:|           |:.
Human   152 SFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISGPLGFFYIY 216

  Fly   197 AGLMNSVGMLSSRIEESNMADLIMGVCAIVFLLLLELLDRVANNEKRNKILRI------------ 249
            |.:..::  .|.|:|.     |::.:.:||.|:|::.|    |.:.:.||..:
Human   217 AYVFENI--KSVRLEA-----LLLSLLSIVVLVLVKEL----NEQFKRKIKVVLPVDLVLIIAAS 270

  Fly   250 FCRYLSTSRNTLIVLIAAIVSFIWIQKCGQVPYALSKNALSTLPNFTVPSFHIETAERNYSIWEV 314
            |..|.:...||           ..::..|.:|..        :|:...|..:|.:|        |
Human   271 FACYCTNMENT-----------YGLEVVGHIPQG--------IPSPRAPPMNILSA--------V 308

  Fly   315 LKELNIGIIVIPIVGILTNISIGKLTPKGL---VDTNQELLTVGLCNMFGSCVQAMPSSGAFTRY 376
            :.|    ...:.:||.:.::::.:.:.|..   :|.|||.|..||.|:..|....:||:.|..|.
Human   309 ITE----AFGVALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRT 369

  Fly   377 AISTACGLRTPMANLYLGIIVLLALSYLSPYFNYIPEATLAAILICSI-FTLLDFKLPMRLWRDS 440
            |...:.|.:|.:|.|...|.||:.:..:.|...::|...||:|::..: ..|:.|:...:.|...
Human   370 AGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVD 434

  Fly   441 KRDFATWLLCFCVSVLFGVEVGLFVSIVVTALHLLFLWARP-----------EIRVKIEQLDE-M 493
            |.|:..|:..:..::.|...|||...:|.|...::..:.|.           |.:||.|...| :
Human   435 KIDWGIWVSTYVFTICFAANVGLLFGVVCTIAIVIGRFPRAMTVSIKNMKEMEFKVKTEMDSETL 499

  Fly   494 QYIRVTPSNG---------IYFPAINYLRERVLKACEQ 522
            |.:::...|.         .|...:|.:::.  .||.|
Human   500 QQVKIISINNPLVFLNAKKFYTDLMNMIQKE--NACNQ 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	PRK11660	50..557	CDD:481320	125/548 (23%)
SLC26A7	NP_599028.1	PRK11660	33..637	CDD:481320	125/548 (23%)