DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5404 and slc26a3.2

DIOPT Version :9

Sequence 1:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	XP_031754873.1	Gene:	slc26a3.2 / 100485314	XenbaseID:	XB-GENE-486240	Length:	757	Species:	Xenopus tropicalis

Alignment Length:	535	Identity:	151/535 - (28%)
Similarity:	248/535 - (46%)	Gaps:	104/535 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VPVFQWLPLYS-TEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSI 112
            :||..|||.|. .||.:.|.|:|:|.||..:.:.:|.||||.:...|||.::|...::|..|||.
Frog    58 LPVLTWLPAYRFKEWLLSDIISGVTTGLVAVLQGLAYALLANVAPGYGLYTSFFPVVVYFFFGSS 122

  Fly   113 DKVIIGPTSLVALV--SVQFTV--GRPIEF-------------------AFLLTFLSGIVQIIMG 154
            ..|..||..:|:|:  ||..:|  |....|                   |..|.||.||:|:.:|
Frog   123 RHVSAGPFPVVSLMVGSVVASVVPGDTTSFSNSTNGTNEALIEQQRMIVASSLCFLVGIIQLALG 187

  Fly   155 TMRMGFIFEFISMPVIKAFSSATAILVIESQLKVLLGIKY-LVAG---LMNSVGMLSSRIEESNM 215
            .:::|||..::|.|:|..|::|.||.|:.||||.:.|||. ..:|   :..|:..:.|:|..:|:
Frog   188 LLQVGFIVIYLSDPLINGFTTAAAIEVVVSQLKYMFGIKIPSFSGPLSIFYSLESIFSQITSTNI 252

  Fly   216 ADLIMGVCAIVFLLLLELLDRVANNEKRNK---------ILRIFCRYLSTSRN----TLIVLIAA 267
            .|||:|:..:|.:.:::.|    |.:.:.|         ||.|....||...|    ..:..:.|
Frog   253 PDLIIGIIIMVLVYIVKEL----NVKYKAKLPVPIPIEIILTIITAGLSYGFNFKDRFQVTTVGA 313

  Fly   268 IVSFIWIQKCGQVPYALSKNALSTLPNFTVPSFHIETAERNYSIWEVLKELNIGIIVIPIVGILT 332
                  |||..|.|.|              ||.            ||.:........|.|||...
Frog   314 ------IQKGYQPPLA--------------PSI------------EVFQTTIANAFSIAIVGFAV 346

  Fly   333 NISIGK---LTPKGLVDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLG 394
            ..|:.|   :.....||.||||:..||.|:.....:...:|.:.:|.::..:.|.:|.:|.:..|
Frog   347 AFSVAKVYAIKHNYNVDGNQELIAFGLSNIVCGSFRGFAASTSLSRSSVQESTGGKTQVAGIISG 411

  Fly   395 IIVL---LALSYLSPYFNYIPEATLAAILICSI-FTLLDF-KLPMRLWRDSKRDFATWLLCFCVS 454
            ||||   ||:.||   ...:|::.||.::|.:: ..|:.| ::|:...|| |.|...|:|.|..:
Frog   412 IIVLIVTLAVGYL---LEPLPKSVLAGVIIINLKGMLMKFNEIPVLFKRD-KFDCLVWILTFIAA 472

  Fly   455 VLFGVEVGLFVSIVVTALHLLFLWARPEIRV--KIEQLD----EMQYIRVTPSNGI--------- 504
            :|.|:::||.|.:.:..|.::|....|:..|  .:.:.|    :..|..:....|:
Frog   473 LLLGLDLGLAVGVGIELLTVVFRVQFPKYSVIANVGRTDIYRNKKDYSEIYEPEGVKIFRSPAPL 537

  Fly   505 YFPAINYLRERVLKA 519
            :|...::.|::::.|
Frog   538 FFANADFFRDKIIAA 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5404	NP_650482.1	sulP	50..557	CDD:273284	151/534 (28%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	4/31 (13%)
slc26a3.2	XP_031754873.1	sulP	59..710	CDD:273284	151/534 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910