Protein Alignment AOX4 and LOC5667145

DIOPT Version :10

• Sequence 1: NP_650478.1
• Gene: AOX4 / 41897
• FlyBaseID: FBgn0038350
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_001688833.2
• Gene: LOC5667145 / 5667145
• VectorBaseID: AGAMI1_004947
• Length: 1270
• Species: Anopheles gambiae
• Alignment Length: 1291
• Identity: 583/1291 - (45%)
• Similarity: 826/1291 - (63%)
• Gaps: 58/1291 - (4%)

  Fly     1 MSTTFTINGQPYAVNLTDLPPDITLNTFIREHAQLTATKFMCLEGGCGACVCAVSDGKS------ 59
            |:..|||||:.:.|..|::..:::||||||.||.|:.||||||||||||||..:|....
Mosquito     1 MAVVFTINGKVFNVQATEINVNVSLNTFIRNHAHLSGTKFMCLEGGCGACVVNLSGAHPVTGDVF 65

  Fly    60 TWTVNSCLKLLNTCAQLEIITCEGLGNQVTGYHPIQKRLAKMNGTQCGFCSPGFVMNMYGLMEQH 124
            ::.|||||..:..|..::|.|.||:|::..|||..||.||..||||||:||||.|||||.|:|..
Mosquito    66 SYAVNSCLFPVLACHGMDITTVEGIGDKQRGYHATQKLLAHFNGTQCGYCSPGMVMNMYSLLEAK 130

  Fly   125 GGRVTMEEVENSFGGNICRCTGYRPILDAMKSFAVDSTVEVSEESVDIEDLNLKARNCPRSGKVC 189
            .|:|||||:||||||||||||||||||||.|:.|||:..::..:..|||||   .:.||::|..|
Mosquito   131 KGKVTMEEIENSFGGNICRCTGYRPILDAFKALAVDADPKLKAKCQDIEDL---TKICPKTGSAC 192

  Fly   190 KGTCRQS---------KLIYEDGSQWYWPSTLAEIFEALENVGDSEEFMLVGGNTAHGVYRRSPD 245
            .|.|..:         .|.:|:..:|:....:::||...|::|| :.:.|:||||||||||||..
Mosquito   193 AGKCAAAGKTNPNKGLHLSFEEQKEWHKVYNVSDIFAIFESIGD-KPYTLIGGNTAHGVYRRSDG 256

  Fly   246 IKHFIDVNGVEDLHQYSSDKEKLTLGASLSLTETMEIIQSTSKQ-SGFEYLEVLWHHIDLVANVP 309
            |:.|||:|.|::| :.||....||:||..||||.|:::.:|:|| :.|.|.|.:..||||:||||
Mosquito   257 IQVFIDINAVQEL-RTSSVGSSLTVGAGTSLTELMDLLTNTAKQNNNFSYFEHMVRHIDLIANVP 320

  Fly   310 VRNSGTLAGNICTKKEHPEFPSDIFISFEALDVKVVAMKGIDDEKEMTLEEFLG-DTDRKMLLKA 373
            |||:||:|||:..|.:|.|||||:::..||.:..:..::.......:...:::. :.::|:||..
Mosquito   321 VRNTGTIAGNLSIKNQHNEFPSDLYLILEAANATLTILESQGKTSTVRPSQYVTMNMNKKLLLNV 385

  Fly   374 FILPRYPKDMYIYDSFKIMPRAQNAHAYVNAGFLLELDGNSMVKSARICFGGIRPDFIHATDIEQ 438
            .:.|.|| .:|:|.:|||||||||||||||..||::|:|:.:: |:.||||||.|.|.||...|:
Mosquito   386 ILPPLYP-SVYVYRTFKIMPRAQNAHAYVNGAFLIKLEGSEII-SSNICFGGIDPQFTHALKTEE 448

  Fly   439 LMVGHSPYESNLVEQTFNKLESLVKPDEVLPDASPAYRSKLACGLLYKFLLKHAPDAE--VSGKF 501
            .:.|.:...:..::.....|.:.:.||.|||||:|.||..||..|.|||.|:.|....  :..::
Mosquito   449 FLKGKNLLTNETIQGALKTLAAELNPDWVLPDAAPEYRKNLALSLFYKFTLQVASVLRFPLKNEY 513

  Fly   502 KSGGELLQRPLSSGLQLFQTNKQ--TYPVTQGVQKLEGMIQCSGEATYMNDVLTTSNSVYCAFVG 564
            ||||.:|.|.:|||.|.::||:|  .:.:.:.:.|:|.:.|.||||.|:||:.|....:|.|||.
Mosquito   514 KSGGSVLSRAISSGAQQYETNQQQEQWSLIKKIPKIEALYQTSGEAKYINDLPTLPGELYAAFVL 578

  Fly   565 ATKVGATIDQIDATEALQHPGVVAFYTAKDIPGTNTF--CEPSFGYEAEEIFCSGMVRHSEQPVG 627
            .|||.|.|...||.||||.|||:||||||||||.|.|  .:..|....||:||||.:.:..||||
Mosquito   579 GTKVHANIASFDAEEALQIPGVIAFYTAKDIPGVNDFMPVKSEFSPNVEEVFCSGRILYHGQPVG 643

  Fly   628 VIVALTADQAQRATKLVKISYSSPSSNFKLMPSLKDVFSSETPDTSRIIPLVISKLKEVKFSDK- 691
            :::|.|.:.||:|.|.|.|.||:.:....::|::|||..::..|  |::.:      :..|:.:
Mosquito   644 LVLADTFEAAQKAAKTVCIHYSTDTVTETILPTVKDVADAKRHD--RVVNI------DYGFTGQS 700

  Fly   692 ------PD--LEVRGIFEMGLQYHFTMEPQTTIIIPFEDGLKVFSATQWIDQTQSVIAHTLQMKA 748
                  |:  :.|.|..|.|.|||:|||.||.:.:|.|||::|.:|||.|..||..|:..|.:..
Mosquito   701 YGDATVPESAIHVSGSHESGGQYHYTMETQTCVCLPLEDGMEVHTATQAITLTQIAISQMLSVPE 765

  Fly   749 KDVQLEVRRLGGGYGCKISRGNQVACAAALAAHKLNRPVRFVQSLESMMDCNGKRWACRSEYQCH 813
            ..:.:.|||:|||||.|.||..|||||.|||.|...||||.|.::|:.|...|||:...|.|...
Mosquito   766 NSLNVSVRRIGGGYGGKASRAVQVACACALACHLTKRPVRLVMTIETNMAVVGKRYGVVSNYTAE 830

  Fly   814 VKTSGRIVGLSNDFYEDAGWNTNESP--VQGHSTFTAANCYEFTDSNFKLSGHAVLTDAPSSTWC 876
            |...|||:.|.|:|..|||.|:||:|  :||:    ..|||  ....:.:.....|||:.|:|||
Mosquito   831 VTPEGRILRLHNEFLHDAGCNSNEAPDFMQGY----YGNCY--NKDVWSVVSKTALTDSASNTWC 889

  Fly   877 RAPGSVEGIAMMENIIEHVAFEIQKDPAEVRLANISKKSKMATVFPEFLKTREYYSRKKEIEAFN 941
            |||||.|..||:|:||||:||..:.||..|||.|:...|.|..:...||...||..|..||..||
Mosquito   890 RAPGSTEAYAMIESIIEHIAFVTRSDPLAVRLQNMPNDSPMKPLLQTFLADIEYDRRNGEIAQFN 954

  Fly   942 ANNRWKKRGLGLSLMNFPIIYIGQFPATVTIYHVDGTVVVTHGGIEMGQGMNTKIAQVAAYTLGI 1006
            ..|||:|||:.:..|.:|:.|.|...|.|:|||.||||.:||||||||||:||:.|||||..|||
Mosquito   955 LENRWRKRGIAIVPMEYPVGYFGTLHALVSIYHTDGTVAITHGGIEMGQGINTRAAQVAAKVLGI 1019

  Fly  1007 DLSYVKVESSTSINGANSMVTGYAIGSESVCYAVRKICETLNARLKPVRK--AKATWVETVEAAN 1069
            .:..:.::.:|::...|...|..:|.||:|.::|...||||..|:.|||:  ...:|.:..:..:
Mosquito  1020 PVEKIAIKPTTNLTAPNDFCTQASITSEAVAHSVLIACETLLERIAPVRQQHPDVSWEKLTQLCH 1084

  Fly  1070 AQLINLIASDHYKTGDMQNYHVLGLALSEVEIDVLTGNILIRRVDILEDAGESLSPWIDVGQVEG 1134
            :|.::|.|:..|...::.:|:|..|:.:|:|:|||||.:|::|||||||||::|:|.|::||:||
Mosquito  1085 SQGVDLCATAMYNGVELPSYNVWALSCAEIELDVLTGCVLLQRVDILEDAGKTLNPEIEIGQIEG 1149

  Fly  1135 AFVMGLGYWLSELLIYEGDNGRLLTNRTWNYKPLGAKDIPIDFRVELVHNPRPSSSGFMGSKATG 1199
            ||:||:|.:|:|.|||:...|.|||||:|||:|.||||||:|.|:.|:.| ..:.:|...|||||
Mosquito  1150 AFMMGVGLYLTEALIYDRATGELLTNRSWNYRPPGAKDIPVDLRIRLLQN-TINPTGVQRSKATG 1213

  Fly  1200 EPPCCLAVSVIFALQQALQSARQDAGLPREWLRLGAPTTPETLLLNAGHQVSEFKL 1255
            ||...:||.|:|||:.|:.:||.|||:|.||:.||.|.||:.:|.:.|:...::.|
Mosquito  1214 EPAVNMAVVVLFALRNAINAARTDAGMPSEWIPLGVPCTPDRILRHLGNAYDQYLL 1269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX4	NP_650478.1	PLN02906	24..1240	CDD:215491	571/1251 (46%)
LOC5667145	XP_001688833.2	None