Protein Alignment AOX4 and AOX1

DIOPT Version :10

• Sequence 1: NP_650478.1
• Gene: AOX4 / 41897
• FlyBaseID: FBgn0038350
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_650475.1
• Gene: AOX1 / 41894
• FlyBaseID: FBgn0267408
• Length: 1273
• Species: Drosophila melanogaster
• Alignment Length: 1281
• Identity: 728/1281 - (56%)
• Similarity: 938/1281 - (73%)
• Gaps: 35/1281 - (2%)

  Fly     1 MSTTFTINGQPYAVNLTDLPPDITLNTFIREHAQLTATKFMCLEGGCGACVCAVS-----DGK-S 59
            |:...||||..:.|||:.||.||:|||||||:|.||.|||||.|||||.|||.::     .|: .
  Fly     1 MAGRITINGTSHEVNLSALPADISLNTFIREYAGLTGTKFMCQEGGCGVCVCTLTGIHPETGELR 65

  Fly    60 TWTVNSCLKLLNTCAQLEIITCEGLGNQVTGYHPIQKRLAKMNGTQCGFCSPGFVMNMYGLMEQH 124
            ||.|||||.|||||..||:.|.|||||:..|||.||:|||||||||||:||||.|||||||::..
  Fly    66 TWAVNSCLTLLNTCLGLEVTTSEGLGNKRVGYHAIQQRLAKMNGTQCGYCSPGIVMNMYGLLKSK 130

  Fly   125 GGRVTMEEVENSFGGNICRCTGYRPILDAMKSFAVDSTVEVSEESVDIEDLNLKARNCPRSGKVC 189
            ||:||||||||||||||||||||||||||||||||||.::|..|.:|||||:.|  .||::|:.|
  Fly   131 GGKVTMEEVENSFGGNICRCTGYRPILDAMKSFAVDSNIQVPAECIDIEDLSTK--KCPKTGQTC 193

  Fly   190 KGTCRQSK----LIYEDGSQWYWPSTLAEIFEALEN-VGDSEEFMLVGGNTAHGVYRRSPDIKHF 249
            .|:|::.:    .:|.|||:|.||.:|.::|.||:. |.:...:|||.|||||||||||||||.|
  Fly   194 SGSCKKQQPKGSQLYPDGSRWSWPVSLGDLFAALQGAVKEKLPYMLVAGNTAHGVYRRSPDIKAF 258

  Fly   250 IDVNGVEDL--HQYSSDKEKLTLGASLSLTETMEIIQSTSKQSGFEYLEVLWHHIDLVANVPVRN 312
            |||:|:.:|  |:.|:|...||||.:|||:||||:.:......|||||..:|.|:|.:|||||||
  Fly   259 IDVSGLAELKGHKLSADNSSLTLGGNLSLSETMELCRQLENTKGFEYLSQVWQHLDWIANVPVRN 323

  Fly   313 SGTLAGNICTKKEHPEFPSDIFISFEALDVKVVAMKGIDDEKEMTLEEFLGDTDRKMLLKAFILP 377
            :||||||:..|..|||||||:||..||||.:|:..:.:|.::.::|..:||.:....:::..:|.
  Fly   324 AGTLAGNLSIKHAHPEFPSDVFIVLEALDAQVIVQEAVDKQQTVSLASYLGSSMEGKIIRGLVLR 388

  Fly   378 RYPKDMYIYDSFKIMPRAQNAHAYVNAGFLLELDGNSMVKSARICFGGIRPDFIHATDIEQLMVG 442
            .|||:.:.:||:|||||||||||||||.||:|...::.|||||||||||.|:|:|||.||.|:..
  Fly   389 AYPKERFAFDSYKIMPRAQNAHAYVNAAFLVEFTADAKVKSARICFGGIHPEFVHATAIENLIRD 453

  Fly   443 HSPYESNLVEQTFNKLESLVKPDEVLPDASPAYRSKLACGLLYKFLLKHAPDAE--VSGKFKSGG 505
            .:|:|:.|||:.|.:|.:|::||.|||||||.||.||||||.||||||.|...:  :..:|.:||
  Fly   454 KNPFENGLVEKAFGQLSTLLQPDAVLPDASPVYRRKLACGLFYKFLLKIAAQRKQGLGSRFVTGG 518

  Fly   506 ELLQRPLSSGLQLFQTNKQTYPVTQGVQKLEGMIQCSGEATYMNDVLTTSNSVYCAFVGATKVGA 570
            .||:||:|||.|.|:|.::.||||:..:|.||:|||||||||.||:.|..|.::.|||.|.||||
  Fly   519 SLLKRPVSSGQQSFETFQEHYPVTKATEKHEGLIQCSGEATYSNDLPTQHNQLWAAFVIAKKVGA 583

  Fly   571 TIDQIDATEALQHPGVVAFYTAKDIPGTNTFCEPS-----FGYEAEEIFCSGMVRHSEQPVGVIV 630
            .:.::|...||..|||||:..||||||.| :..|.     |..:.||:|.:|.::...||||:|:
  Fly   584 KVTKVDTQPALDLPGVVAYLDAKDIPGPN-YVGPKIRDQFFFPKDEELFATGEIKFYGQPVGIIL 647

  Fly   631 ALTADQAQRATKLVKISYSSPSSNFKLMPSLK---DVFSSETPDTSRIIPLVISKLKEVKFSDKP 692
            |.:...|.||.:|||::|...:.  :::||||   |...||..:..|:...:.|.:..::..:..
  Fly   648 ANSNSLANRAAELVKLTYEGGAE--EILPSLKAVLDKVGSEAGNNKRLEQPIKSTIDVLQLEEPF 710

  Fly   693 DLEVRGIFEMGLQYHFTMEPQTTIIIPFEDGLKVFSATQWIDQTQSVIAHTLQMKAKDVQLEVRR 757
            |:...|..:||||||:.||||||:::|||.||:|::||||:|.||..||:.|.:|:.|||::.||
  Fly   711 DVSSSGQLDMGLQYHYYMEPQTTVVLPFEGGLQVYAATQWMDLTQDTIANVLNLKSNDVQVKTRR 775

  Fly   758 LGGGYGCKISRGNQVACAAALAAHKLNRPVRFVQSLESMMDCNGKRWACRSEYQCHVKTSGRIVG 822
            :|||||.|.:|.|..|.||||||||||||:||||||||:|...|||||...:|...|:.||:|.|
  Fly   776 IGGGYGGKATRCNLAAAAAALAAHKLNRPIRFVQSLESIMTSLGKRWAFHCDYDFFVQKSGKISG 840

  Fly   823 LSNDFYEDAGWNTNESPVQGHSTFTAANCYEFTDSNFKLSGHAVLTDAPSSTWCRAPGSVEGIAM 887
            :.:.||||||:..||||: ||:...:.|||||:| |:||.|:.|.||:||:|.||||||||||||
  Fly   841 IVSRFYEDAGYLANESPI-GHTVLLSKNCYEFSD-NYKLDGYLVCTDSPSNTPCRAPGSVEGIAM 903

  Fly   888 MENIIEHVAFEIQKDPAEVRLANISKKSKMATVFPEFLKTREYYSRKKEIEAFNANNRWKKRGLG 952
            |||||||:|||...|||:||.||:....||..:.|.||::.:|..||.|..|.|..|||.|||||
  Fly   904 MENIIEHIAFETGVDPADVRFANLLPAHKMGDMMPRFLESTKYRERKAEAIAHNKENRWHKRGLG 968

  Fly   953 LSLMNFPIIYIGQFPATVTIYHVDGTVVVTHGGIEMGQGMNTKIAQVAAYTLGIDLSYVKVESST 1017
            |.:|.:.|.|.||:||||.|||.||||||:||||||||||||||:||||:||||.:..|::|:|.
  Fly   969 LCIMEYQIGYFGQYPATVAIYHSDGTVVVSHGGIEMGQGMNTKISQVAAHTLGIPMEQVRIEASD 1033

  Fly  1018 SINGANSMVTGYAIGSESVCYAVRKICETLNARLKPVRK--AKATWVETVEAANAQLINLIASDH 1080
            :||||||||||.|:|||::|:||||.|||||.||||||:  ....|.:.::.|..:.|||||||.
  Fly  1034 TINGANSMVTGGAVGSETLCFAVRKACETLNERLKPVREEVKPENWQDLIQEAYNRKINLIASDQ 1098

  Fly  1081 YKTGDMQNYHVLGLALSEVEIDVLTGNILIRRVDILEDAGESLSPWIDVGQVEGAFVMGLGYWLS 1145
            .|.|||..|.|.||.|:|||:||||||.::.|||||||.||||:|.:|:||:||||:||||||.|
  Fly  1099 CKQGDMDPYSVCGLCLTEVELDVLTGNYIVGRVDILEDTGESLNPNVDIGQIEGAFMMGLGYWTS 1163

  Fly  1146 ELLIYEGDNGRLLTNRTWNYKPLGAKDIPIDFRVELVHNPR-PSSSGFMGSKATGEPPCCLAVSV 1209
            |.:|.:...|..||||||.|||.||||||.|.|:||:  |: |:.:|||.|||||||..||:::|
  Fly  1164 EQVIADPKTGECLTNRTWTYKPPGAKDIPTDLRIELL--PKSPNKAGFMRSKATGEPAICLSIAV 1226

  Fly  1210 IFALQQALQSARQDAGLPREWLRLGAPTTPETLLLNAGHQVSEFKL 1255
            .|||||||||||.|||:|:.|:.|.||.|||.|:|::|.:.|:|||
  Fly  1227 AFALQQALQSARDDAGVPKSWVTLTAPMTPEHLVLHSGTEPSQFKL 1272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX4	NP_650478.1	PLN02906	24..1240	CDD:215491	707/1241 (57%)
AOX1	NP_650475.1	PLN02906	28..1259	CDD:215491	706/1239 (57%)