Protein Alignment AOX3 and AOX2

DIOPT Version :10

• Sequence 1: NP_650477.1
• Gene: AOX3 / 41896
• FlyBaseID: FBgn0038349
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_732047.2
• Gene: AOX2 / 41895
• FlyBaseID: FBgn0038348
• Length: 1264
• Species: Drosophila melanogaster
• Alignment Length: 1277
• Identity: 749/1277 - (58%)
• Similarity: 961/1277 - (75%)
• Gaps: 37/1277 - (2%)

  Fly     1 MTTKFSINGLPYAVNLTNLPPDITLNTFIREHAQLTATKFMCQEGGCGACICVVR------DGKR 59
            |:.||::||.||.|...:.|||.|||||:|||..|||||:||.|||||:|:||:|      ...:
  Fly     1 MSIKFNVNGFPYEVQAADYPPDTTLNTFLREHLHLTATKYMCLEGGCGSCVCVIRRRHPVTQEVQ 65

  Fly    60 SWAVNSCLTLLNTCAQLEIVTAEGLGNQRTGYNPIQKRLAKMNGTQCGFCSPGFVMNMYGLMEQN 124
            |.|.||||||||||...||:|.||||||.:||:|||||:|:|||||||:||||||||||||:||:
  Fly    66 SRAANSCLTLLNTCDDAEIMTDEGLGNQLSGYHPIQKRVAQMNGTQCGYCSPGFVMNMYGLLEQH 130

  Fly   125 EGKVTMAEVENSFGGNICRCTGYRPILDAMKSFAVDSNIAIPAECGDIEDLKPRNCPKTGQACSG 189
            .|:|:|::||::||||:|||||||||||||||||||||:.:|||..||||.....||:|||:|.|
  Fly   131 RGQVSMSQVEDAFGGNLCRCTGYRPILDAMKSFAVDSNVEVPAESVDIEDSFELLCPRTGQSCKG 195

  Fly   190 SCLPSTLVYEDGVQWHWPKSLSELFDALDKVKDSEEFMLVAGNTAHGVYRRSTDIKHFIDVQGVE 254
            ||....|......||:|||:|:|||.||.:|.:.|.:||||||||||||||..||:|||||..|.
  Fly   196 SCSRPPLRDHGDSQWYWPKTLTELFGALSQVANGELYMLVAGNTAHGVYRRPRDIRHFIDVNMVP 260

  Fly   255 ELHQHSSEGQQLKLGANLSLTQTMEIIRTTSKQPGFEYLDVLWNHIDLIANVPVRNSGTLAGNIS 319
            ||.|:|.|...|.||.|::||..|::....:|:|||||...||.|.:|||||||||:|||||||:
  Fly   261 ELRQYSIETDHLLLGGNVTLTDAMQVFLLAAKRPGFEYCAQLWQHFNLIANVPVRNNGTLAGNIN 325

  Fly   320 IKKQNPEFPSDIFISFEALNVKVVALKNAADEKEMSLAEYLGTNDKKLVLKTFVLPAYPKDKYIY 384
            ||||:.|||||:||:||||:|.|:...|.:.::.|:|..|||....||||..|:|.|||||::::
  Fly   326 IKKQHFEFPSDVFITFEALDVHVLVYDNPSTQRVMNLLTYLGDTTSKLVLGGFILKAYPKDRFLF 390

  Fly   385 ESYKIMPRAQNAHAYVNAAFLLELE--ADNKVKSARICFGGIRPDFIHASAIEKLLVGQNPYESS 447
            .||||:|||||.||||||.||:|.:  ....|.|||||||.||||:||...:|:||.|::.|:.:
  Fly   391 RSYKILPRAQNVHAYVNAGFLIEWQDIQHRIVHSARICFGNIRPDYIHDDQVEQLLPGRDLYDPA 455

  Fly   448 LVEQTFTKLEDLIKPDEVLPDASPAYRSKLACGLFYKFLLKHAPVAEVGEKFRSGGQILQRPLSS 512
            .|.|.|.:|...::|:|..|:|||.||..|||.|.|||||..||...|.|:||:||.:|:|||||
  Fly   456 TVAQIFQELPASLQPEERPPEASPEYRQMLACSLLYKFLLATAPKERVRERFRTGGLLLERPLSS 520

  Fly   513 GLQVFQTQKKNYPVTQAVEKVEGMIQCSGEATYMNDVLTTSNTLHCAFVGATKVGSTIDSIDASE 577
            |.|.|:|.||||||||.|:|:||:||||||||||||:|||||.:|||||.|.:||:||:.||.|.
  Fly   521 GSQSFETIKKNYPVTQPVQKLEGLIQCSGEATYMNDLLTTSNAVHCAFVTAKRVGATIEQIDPSA 585

  Fly   578 ALKQPGVIAFYSAKDIPGTNTF-----CEPSFGFEVEEIFCSGLVRHSEQPAGVIVALTADQAHR 637
            ||:..||:|||||:||||:|.|     ..|    ||:|:|.:|.|::.:||.|||.|||.|.|..
  Fly   586 ALQCKGVVAFYSAEDIPGSNNFVLVNQLTP----EVDEVFVAGRVKYFDQPLGVIAALTHDAAVY 646

  Fly   638 AAKLVRISYSNPSSDFKLQPSLGDVFASPTPDSSRIVPASKSTSKKIKFSEQPDKEV--RGIFQM 700
            ||.||.::|:....  |:..::..|.|....|  |||...|.|.:.:|.......:|  |||.::
  Fly   647 AATLVVVTYARDQR--KIFTTMNQVLAEKQTD--RIVSTKKDTVEPLKLPPLAPGDVLGRGILEL 707

  Fly   701 GLQYHFTMEPQTTVAIPFEDGLKIFSATQWMDQTQSVIAHMLQVKAKDVQLQVRRLGGGYGSKIT 765
            ..|||||||||||:.:|.::.|:::.||||||.||..|||||:|....:||||||:||.||:|:|
  Fly   708 ASQYHFTMEPQTTIVVPLDNILQVYCATQWMDATQGAIAHMLKVSVNSIQLQVRRVGGAYGAKVT 772

  Fly   766 RGNQVACAASLVAYKLNRPVRFVQSLESMMDCNGKRWACRSDYKCHIKDNGKIVGLTNDFYEDAG 830
            |||.||||.:|||.||.||.||||::||||:..||||||||||:...:.||.|:.|:|::|||:|
  Fly   773 RGNIVACATALVASKLRRPARFVQTIESMMETIGKRWACRSDYEFRARANGSIIMLSNNYYEDSG 837

  Fly   831 WSPNESPIEGHSTFTAVNCYDLNGDNFKNNGNAVLTDAPSSTWCRAPGSVEGIAMIENIIEHVAF 895
            .:.||:.::..:.....|.|:|...|::..|:|:.||||||||||||||.|||||.|..:||:||
  Fly   838 CNLNENVVDFLTLPILRNVYNLTDANYRTQGSAIRTDAPSSTWCRAPGSAEGIAMTETALEHIAF 902

  Fly   896 EVQKDPAEVRLANIAAGNKISELLPQFLESREYAQRKKEIESHNAKNRWTKRGLGLAVMDYPI-- 958
            ..|.|||:|||.|:..|||:.:|||:||.|.||.:|:.:|...|::|||.|||||||:|.:|:
  Fly   903 TCQLDPADVRLVNLQPGNKMVQLLPKFLASTEYHKRRDQINLFNSQNRWRKRGLGLALMSFPLNT 967

  Fly   959 ---FYFGQYPATVAIYHVDGTVVVTHGGIEMGQGMNTKVAQVAAYTLGIDLSFIKVESSDTINGA 1020
               |   .||.||||||.||:||::|||||:|||:|||.|||||:.||:.|..::||:|:|:|||
  Fly   968 TVAF---NYPVTVAIYHEDGSVVISHGGIEIGQGVNTKAAQVAAFVLGVPLDQVRVEASNTVNGA 1029

  Fly  1021 NSMVTGGAVGSESLCYAVRKACETLNSRLEPVKKK---DASWIETVEAAYGKSINLIASDHYKKG 1082
            |||:|..::.||.:..||||||:|||.||.|||::   .|||::.::||:.:|:.|||::.|:.|
  Fly  1030 NSMLTANSMTSEMIGLAVRKACDTLNKRLAPVKERLGPRASWVQVLQAAFLQSVFLIATESYRLG 1094

  Fly  1083 DMQNYHIYGLALTEVELDVLTGNSQIKRVDILEDAGESLSPWIDIGQIEGAFVMCLGYWMSEQLV 1147
            |:.||:|:||:|||:|||:||||..|:||||||||||||||.||:||:||||||.|||:::||||
  Fly  1095 DIPNYNIFGLSLTELELDILTGNHLIRRVDILEDAGESLSPHIDVGQVEGAFVMGLGYYLTEQLV 1159

  Fly  1148 YDRETGRLLTNRTWNYKPPGAKDIPIDFRIELIQK-PNPSGAGFMRSKATGEPPCCLAVSVVFAL 1211
            |||:||::||||||||.|||||||||||||||:|| |||  .|||||||||||..||||..:||:
  Fly  1160 YDRQTGQILTNRTWNYHPPGAKDIPIDFRIELLQKSPNP--VGFMRSKATGEPALCLAVGALFAM 1222

  Fly  1212 RQALDSARHDAGLPREWVRLGAPTTPETLVVNAGHEAASFRL 1253
            :.|:.|||:|||||||||||||||||||:|:|:|.:..:|.|
  Fly  1223 QHAIQSARNDAGLPREWVRLGAPTTPETVVLNSGSQVEAFAL 1264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX3	NP_650477.1	PLN02906	24..1238	CDD:215491	730/1237 (59%)
AOX2	NP_732047.2	PLN02906	24..1251	CDD:215491	732/1239 (59%)