Protein Alignment AOX2 and LOC5667147

DIOPT Version :10

• Sequence 1: NP_732047.2
• Gene: AOX2 / 41895
• FlyBaseID: FBgn0038348
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_061505525.1
• Gene: LOC5667147 / 5667147
• VectorBaseID: AGAMI1_001461
• Length: 1338
• Species: Anopheles gambiae
• Alignment Length: 1292
• Identity: 613/1292 - (47%)
• Similarity: 839/1292 - (64%)
• Gaps: 60/1292 - (4%)

  Fly     3 IKFNVNGFPYEVQAADYPPDTTLNTFLREHLHLTATKYMCLEGGCGSCVCVIRRRHPVTQEVQSR 67
            :.|.:||..|..:..:...||:||||:|.|.||:.:|:||||||||:|:..:...||||:|.:|.
Mosquito    76 VTFTINGIAYTAKTENLSLDTSLNTFIRNHAHLSGSKFMCLEGGCGACIVNVSGLHPVTKETKSW 140

  Fly    68 AANSCLTLLNTCDDAEIMTDEGLGNQLSGYHPIQKRVAQMNGTQCGYCSPGFVMNMYGLLEQHRG 132
            :|||||..:..|...::.|.|.|||:..||||||:|:|.|||:||||||||.||.||.|::..:|
Mosquito   141 SANSCLLPVFACHGLDVKTVESLGNKRDGYHPIQERLAHMNGSQCGYCSPGMVMTMYSLMKSKQG 205

  Fly   133 QVSMSQVEDAFGGNLCRCTGYRPILDAMKSFAVDSNVEVPAESVDIEDSFEL-LCPRTGQSCKGS 196
            .|||..||:|.|||:||||||||||||.||.|..|..|:|    |||   || :||:|..:|...
Mosquito   206 AVSMEDVENALGGNICRCTGYRPILDAFKSLASVSVQELP----DIE---ELKICPKTNTACSAK 263

  Fly   197 C---------SRPPLRDHGDS-QWYWPKTLTELFGALSQVANGELYMLVAGNTAHGVYRRPRDIR 251
            |         .||.....||. :|:...||.|:|...|::.. ..|||:|||||||||||...::
Mosquito   264 CPVAASLIEPGRPVHLVAGDDREWHKVFTLAEIFAIFSKIGT-RPYMLLAGNTAHGVYRRSESLQ 327

  Fly   252 HFIDVNMVPELRQYSIETDHLLLGGNVTLTDAMQVF-LLAAKRPGFEYCAQLWQHFNLIANVPVR 315
            .|||:..|.|||.|.:.|..|::|.|||||:.:::. ..|.|||.|.||.::.:|..||||..:|
Mosquito   328 VFIDITSVEELRNYFLRTGELIVGANVTLTEFIEILDKTATKRPNFRYCGEIARHLRLIANPAIR 392

  Fly   316 NNGTLAGNINIKKQHFEFPSDVFITFEALDVHVLVYDNPSTQRVMNLLTYLG-DTTSKLVLGGFI 379
            |.||:|||:.:|.||.:|||||:|..||:...::|.|:.:|.:......|.. |.|.||:.   :
Mosquito   393 NAGTIAGNLTLKNQHPQFPSDVYILLEAVGAKLIVADSLATYQAKTAQEYSQMDLTKKLLK---V 454

  Fly   380 LKAYPKDRF--LFRSYKILPRAQNVHAYVNAGFLIEWQDIQHRIVHSARICFGNIRPDYIHDDQV 442
            :.....|.|  .||||::.|||||.||||||.||:.... ....|.||.:|||.|.|.:.|..:.
Mosquito   455 VSLPLTDSFNTAFRSYRVAPRAQNAHAYVNAAFLLRMAS-DKMTVKSATLCFGGINPKFTHASRT 518

  Fly   443 EQLLPGRDLYDPATVAQIFQELPASLQPEERPPEASPEYRQMLACSLLYKFLLATAPKERV--RE 505
            |:||.|:.|::...:.|....|.:.|||:...|:||.|||..||.||.|||||:.|....|  ..
Mosquito   519 EKLLAGKQLFNNTIIQQAINTLASELQPDWILPDASAEYRSGLAVSLFYKFLLSVATDNNVPLDP 583

  Fly   506 RFRTGGLLLERPLSSGSQSFETIKKNYPVTQPVQKLEGLIQCSGEATYMNDLLTTSNAVHCAFVT 570
            |||:|..:|:||||||.|.::|.|||:|||:.|.|||||:|.||||.|.||.......::.|||.
Mosquito   584 RFRSGSAMLQRPLSSGQQYYDTNKKNWPVTKYVPKLEGLVQTSGEAKYTNDFPPFPGELYAAFVV 648

  Fly   571 AKRVGATIEQIDPSAALQCKGVVAFYSAEDIPGSNNFVL--VNQLTPEVDEVFVAGRVKYFDQPL 633
            |.::.:||.:|||:.||:..||:|||||:.|||.|||:.  ::...|:|:|:|.:|||.:..||:
Mosquito   649 ATQLNSTIGKIDPTDALKLPGVIAFYSAKHIPGVNNFMSDGMHFYFPDVEEIFCSGRVLFHGQPV 713

  Fly   634 GVIAALTHDAAVYAATLVVVTYAR-DQRKIFTTMNQVLAEKQTDRIV--------STKKDTVEPL 689
            |||.|...|.||.||..|.:.|.| ....|..|:..||..:..||||        |.:.|.....
Mosquito   714 GVIVAERFDQAVRAAKQVNIIYERISDEPICPTIKAVLTHRSKDRIVSQPASSRTSQQVDVQVSK 778

  Fly   690 KLPPLAPGDVLGRGILELASQYHFTMEPQTTIVVPLDNILQVYCATQWMDATQGAIAHMLKVSVN 754
            ||          :|.||||.|||:|:||||.:.||::|.:.||.|||::|..|.|||..|.|..|
Mosquito   779 KL----------QGTLELAGQYHYTLEPQTCVCVPMENGMDVYAATQFIDLVQVAIAAALNVPEN 833

  Fly   755 SIQLQVRRVGGAYGAKVTRGNIVACATALVASKLRRPARFVQTIESMMETIGKRWACRSDYEFRA 819
            |:.|.|||:||.:|||:||.:.:|||.||.|...|||.||:.|||:.|.|||||::|.|:|:...
Mosquito   834 SLNLTVRRLGGGFGAKLTRSSHIACACALAAHLTRRPVRFIMTIEANMSTIGKRYSCVSNYQVEV 898

  Fly   820 RANGSIIMLSNNYYEDSGCNLNENVVDFLTLPILRNVYNLT--DANYRTQGSAIRTDAPSSTWCR 882
            .:.|.|:.|:||:.:|.||||||||||...:     |:.|:  .:.::.:||::.|||||:||.|
Mosquito   899 DSKGKILKLANNFMQDYGCNLNENVVDDAKV-----VFGLSYNSSAWKVEGSSVLTDAPSNTWMR 958

  Fly   883 APGSAEGIAMTETALEHIAFTCQLDPADVRLVNLQPGNKMVQLLPKFLASTEYHKRRDQINLFNS 947
            ||.:.|||||.||.:||||:...:||..|||.|:..|:|:|.|:|:|....|:.||:..::.||:
Mosquito   959 APATTEGIAMVETIMEHIAWITGVDPMQVRLSNMPAGSKLVTLMPQFRKDVEFDKRKQAVDEFNA 1023

  Fly   948 QNRWRKRGLGLALMSFPLNTTVAFNYPVTVAIYHEDGSVVISHGGIEIGQGVNTKAAQVAAFVLG 1012
            :|||||||:.:..|.|||....|.:  ..|:||.:||:|.|||||||||||:||||||||||.||
Mosquito  1024 KNRWRKRGIAMVPMQFPLVHYGALH--AQVSIYAKDGTVAISHGGIEIGQGINTKAAQVAAFTLG 1086

  Fly  1013 VPLDQVRVEASNTVNGANSMLTANSMTSEMIGLAVRKACDTLNKRLAPVKERLGPRASWVQVLQA 1077
            :||:::.::.:.::...|:.:|..|||||::..|::|||:.||.||.|||:.| ..|.|.::.|.
Mosquito  1087 IPLEKIAIKPTTSMTSPNAAMTGGSMTSEVVCYAIKKACEILNARLQPVKDEL-KAAPWEKITQT 1150

  Fly  1078 AFLQSVFLIATESYRLGDIPNYNIFGLSLTELELDILTGNHLIRRVDILEDAGESLSPHIDVGQV 1142
            .:.:.:.|.....|:..|:..|:|:|||..|:|:|:|||...:.|||||||.|||:||.|||||:
Mosquito  1151 CYARDIDLSVLYQYKKSDLKPYSIWGLSCAEVEIDVLTGQIQLSRVDILEDTGESISPGIDVGQI 1215

  Fly  1143 EGAFVMGLGYYLTEQLVYDRQTGQILTNRTWNYHPPGAKDIPIDFRIELLQKSPNPVGFMRSKAT 1207
            |||||||:||:|||.||||...|.:||||:|||.||||||||:||||.|:|...||.|.:|||||
Mosquito  1216 EGAFVMGIGYWLTEVLVYDMSNGALLTNRSWNYKPPGAKDIPVDFRIRLIQTGDNPYGVLRSKAT 1280

  Fly  1208 GEPALCLAVGALFAMQHAIQSARNDAGLPREWVRLGAPTTPETVVLNSGSQVEAFAL 1264
            |||||.:|:..:||:::|::||:.|||.|.:|:.||:.:||:.:.|.:.:..|.:.|
Mosquito  1281 GEPALTMAIVVVFALRYALRSAQKDAGRPDDWIALGSASTPDQIFLKASNAYEQYKL 1337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX2	NP_732047.2	PLN02906	24..1251	CDD:215491	604/1256 (48%)
LOC5667147	XP_061505525.1	None