Protein Alignment AOX2 and xdh

DIOPT Version :10

• Sequence 1: NP_732047.2
• Gene: AOX2 / 41895
• FlyBaseID: FBgn0038348
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_688983.3
• Gene: xdh / 560486
• ZFINID: ZDB-GENE-070719-9
• Length: 1351
• Species: Danio rerio
• Alignment Length: 1347
• Identity: 409/1347 - (30%)
• Similarity: 647/1347 - (48%)
• Gaps: 143/1347 - (10%)

  Fly     5 FNVNGFPYEVQAADYPPDTTLNTFLREHLHLTATKYMCLEGGCGSCVCVIRRRHPVTQEVQSRAA 69
            |.|||.....:.||  |:.||.|:||..|.||.||..|.|||||:|..::.:.||....:...|.
Zfish    21 FFVNGKKITEKNAD--PEITLLTYLRRSLGLTGTKLGCAEGGCGACTVMVSKYHPNQNRIIHYAI 83

  Fly    70 NSCLTLLNTCDDAEIMTDEGLGNQLSGYHPIQKRVAQMNGTQCGYCSPGFVMNMYGLLEQHRGQV 134
            |:||..|.:.....:.|.||:|:..|..||:|:|:|:.:|:|||:|:||.||:||.|| ::..|.
Zfish    84 NACLAPLCSLHHCAVTTVEGIGSVASKLHPVQERIAKAHGSQCGFCTPGIVMSMYALL-RNNPQP 147

  Fly   135 SMSQVEDAFGGNLCRCTGYRPILDAMKSFAVD-----------------------SNVEVP---- 172
            :|..:::||.|||||||||||||:..::|..|                       .|...|
Zfish   148 TMHDIQEAFQGNLCRCTGYRPILEGYRTFTKDGGCCGGKSQTNGCCMTNGNTQEHENSAHPVQHL 212

  Fly   173 ---AESVDIEDSFELLCPRTGQSCKGSCSRPPLRDHGDS-QWYWPKTLTELFGALSQVANGELYM 233
               :|.:.::.:.|::.|....|......| .:|..|:. .|..|.:|.||....:...|.:
Zfish   213 YDQSEFMPLDPTQEIIFPPELVSLSKQTQR-EMRFVGERVLWIQPCSLKELLELKATYPNAK--- 273

  Fly   234 LVAGNTAHGVYRRPRDIRH--FIDVNMVPELRQYSIETDHLLLGGNVTLTDAMQVFLLAAKR-PG 295
            ||.|||..|:..:.:::.:  .:....:|||.......|.:.:|.:||||....|...|.|: |.
Zfish   274 LVVGNTEVGIEMKFKNLLYPVILAPAYIPELNIIQHTQDGIEVGASVTLTVLGDVLQSAVKKLPA 338

  Fly   296 F--EYCAQLWQHFNLIANVPVRNNGTLAGNINIKKQHFEFP-SDVFITFEALDVHVLVYDNPSTQ 357
            :  |....:.:.....|...:||...:.|||....     | ||:...|.|....:.|. :...:
Zfish   339 YQTEVFKAVLEQLRWFAGQQIRNVAAVGGNIMTAS-----PISDLNPVFMAAGCKLTVM-SKGEK 397

  Fly   358 RVMNL--LTYLGDTTSKLVLGGFILK---AYPKDRFLFRSYKILPRAQNVHAYVNAGFLIEWQDI 417
            ||:.:  ..:.|...:.|.....:|.   .|.|....|.::|..||.::..:.|..|..:.:::
Zfish   398 RVLEMDDKFFTGYRKTALKPEEILLSIEIPYTKKGQYFSAFKQSPRKEDDISIVTCGMNVYFKE- 461

  Fly   418 QHRIVHSARICFGNIRPDYIHDDQVEQLLPGR----DLYDPATVAQIFQELPASLQPEERPPEAS 478
            |...|.|.||.:|.:.|..:........|..|    ||.:.| .:.:.:|:  ||.|.  .|...
Zfish   462 QSNTVQSIRISYGGMAPVTVLATATCNKLLNRQWNEDLLEEA-CSSLAEEM--SLSPS--APGGM 521

  Fly   479 PEYRQMLACSLLYKFLLATAPK------------ERVRERFRTGGLLLERPLSSGSQSFETI--- 528
            ..||:.|..||.|||.|....|            |.::..|.|...|.:....|..|.::.:
Zfish   522 VTYRRTLTISLFYKFFLTVQHKLAVSLQMEGVTVEDIQPEFSTATELFQVDTPSSVQLYQEVPPG 586

  Fly   529 -KKNYPVTQPVQKLEGLIQCSGEATYMNDLLTTSNAVHCAFVTAKRVGATIEQIDPSAALQCKGV 592
             .::..|..|:..|..|.|.:|||.|.:|:....|.:|.|.||:.:..|.|:.||.|:|:...||
Zfish   587 QNEDDVVGHPIIHLSALKQATGEAVYCDDMPCYENELHLALVTSTKAHALIKSIDTSSAMSVPGV 651

  Fly   593 VAFYSAEDIPGSNNFVLVNQLTPEV--DE-VFVAGRVKYFDQPLGVIAALTHDAAVYAATLVVVT 654
            |||.||:||||||       :|..|  || ||...:|......:|.|.|.|...|..||.:|.::
Zfish   652 VAFISAKDIPGSN-------MTGPVVYDETVFADDKVTCVGHIVGAIVADTQAHAQRAAKVVKIS 709

  Fly   655 YARDQRKIFTTMNQVLAEKQTDRIVST--KKDTVEPLKLPPLAPGDVLGRGILELASQYHFTMEP 717
            | .:.:.:..|:...:..|.....|.|  |.|..:..|     ..|.:..|.:.:..|..|.:|.
Zfish   710 Y-EELKPVIVTIQDAINNKSFFEPVRTIEKGDVAQGFK-----DSDHILHGEMHIGGQEQFYLET 768

  Fly   718 QTTIVVPL--DNILQVYCATQWMDATQGAIAHMLKVSVNSIQLQVRRVGGAYGAKVTRGNIVACA 780
            ..|:.||.  |..::::.:||....||..:|..|.|..|.:..:|:|:||.:|.|.:|..|::..
Zfish   769 NCTLAVPRGEDGEMELFVSTQSASKTQALVAKALGVPANRVVCRVKRMGGGFGGKESRSTILSTV 833

  Fly   781 TALVASKLRRPARFVQTIESMMETIGKRWACRSDYEFRARANGSIIMLSNNYYEDSGCNLNENVV 845
            .|:.|.|::.|.|.:...:..|...|.|......|:.....||.::.|....|.::|.:|:
Zfish   834 VAVAAQKVKCPVRCMLDRDEDMLVTGGRHPFFGQYKVGFMKNGRVMALEVTLYSNAGNSLD---- 894

  Fly   846 DFLTLPILR-------NVYNLTDANYRTQGSAIRTDAPSSTWCRAPGSAEGIAMTETALEHIAFT 903
              |:|.||.       |.||:  .|....|...:|:.||::..|..|..:|:.:.|:.:..:|.:
Zfish   895 --LSLSILERALFHMDNSYNI--PNICGTGYMCKTNLPSNSAFRGFGGPQGMMIAESWMSDVALS 955

  Fly   904 CQLDPADVRLVNLQPGNKMV---QLLPKF---------LASTEYHKRRDQINLFNSQNRWRKRGL 956
            |.|...:||.:|:.....:.   |.|.:|         :..::::||:|.:..:|.|:||.||||
Zfish   956 CGLPAEEVRRMNMYNEGDLTHFNQRLDQFTIARCWEECMQLSDFNKRKDAVEKYNRQHRWTKRGL 1020

  Fly   957 GLALMSFPLNTTVAF-NYPVTVAIYHEDGSVVISHGGIEIGQGVNTKAAQVAAFVLGVPLDQVRV 1020
            .:....|.::.|..| |....:...:.||||:::|||.|:|||::||..|||:..|.:|..::.:
Zfish  1021 SIIPTKFGISFTAVFLNQAGALVHVYSDGSVLLTHGGTEMGQGLHTKMVQVASKTLEIPCTKIHI 1085

  Fly  1021 EASNTVNGANSMLTANSMTSEMIGLAVRKACDTLNKRLAPVKERLGPRASWVQVLQAAFLQSVFL 1085
            ..::|....|:..||.|.:|::.|:||..||.|:.:||.|.||: .|:..|...:.||:...|.|
Zfish  1086 TETSTSTVPNTSPTAASASSDLNGMAVYNACQTILQRLQPFKEK-NPKGCWEDWVTAAYFDRVNL 1149

  Fly  1086 IATESYRLGDIP-----------NYNIFGLSLTELELDILTGNHLIRRVDILEDAGESLSPHIDV 1139
            .|...|:..|:.           ||..:|::::|:|:|.|||:|......|:.|.|:||:|.:|:
Zfish  1150 SANGFYKTPDLGYDFDTNSGRPFNYFSYGVAVSEVEIDCLTGSHKNLHTSIVMDVGKSLNPALDI 1214

  Fly  1140 GQVEGAFVMGLGYYLTEQLVYDRQTGQILTNRTWNYHPPGAKDIPIDFRIELLQKSPNPVGFMRS 1204
            |||||.|:.|||.:..|:|.|. ..|.:.|.....|..|...|||.:.::.||:.:||......|
Zfish  1215 GQVEGGFMQGLGLFTLEELRYS-PDGYLYTRGPGMYKIPAFGDIPSELKVSLLRDAPNDKAIFSS 1278

  Fly  1205 KATGEPALCLAVGALFAMQHAIQSARNDAGLPREWVRLGAPTTPETV 1251
            ||.|||.|.||....:|::.||.:||.::||...: ||.:|.|||.:
Zfish  1279 KAVGEPPLFLAASVFYAIKDAITAARAESGLTGPF-RLDSPATPERI 1324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX2	NP_732047.2	PLN02906	24..1251	CDD:215491	402/1326 (30%)
xdh	XP_688983.3	PLN02906	36..1336	CDD:215491	402/1330 (30%)